ACR 2017

Treatment Options to Explore When Serum Uric Acid Targets Are Not Attained

Treatment Options to Explore When Serum Uric Acid Targets Are Not Attained

Machelle Manuel, PhD, discusses further gout treatment options to consider when target serum urate levels are not attained.

Assessment of Life Expectancy in Scleroderma-Associated Pulmonary Arterial Hypertension

Assessment of Life Expectancy in Scleroderma-Associated Pulmonary Arterial Hypertension

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Patients with scleroderma-associated isolated pulmonary arterial hypertension (SSc-PAH) have a slightly higher mortality risk than patients SSc-PAH with concomitant interstitial lung disease.

Rituximab Effectively Treats Relapsing ANCA-Associated Vasculitis

Rituximab Effectively Treats Relapsing ANCA-Associated Vasculitis

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Results from the largest prospective study of rituximab use in patients with relapsing ANCA-associated vasculitis show that 91.2% of participants achieved remission.

Pulmonary Arterial Hypertension in Systemic Sclerosis: Swift Diagnosis and Effective Treatment

Pulmonary Arterial Hypertension in Systemic Sclerosis: Swift Diagnosis and Effective Treatment

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Rheumatology specialists should be aware of the clinical features of SSc-PAH, as well as the tools available to facilitate a prompt, accurate diagnosis.

Medications Linked With Increased Osteoporotic Fracture Risk in Rheumatoid Arthritis

Medications Linked With Increased Osteoporotic Fracture Risk in Rheumatoid Arthritis

Opioids and SSRIs are linked to an increased risk of osteoporotic fractures in RA patients.

Association Between SLE Disease Activity and Omega Fatty Acids, Vitamin D

Association Between SLE Disease Activity and Omega Fatty Acids, Vitamin D

Low vitamin D is linked with later total organ and renal damage in patients with SLE.

Adalimumab to Sarilumab for Rheumatoid Arthritis: Effect on Physical Function

Adalimumab to Sarilumab for Rheumatoid Arthritis: Effect on Physical Function

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Sarilumab administered every 2 weeks is associated with similar improvements in physical function in adult patients with rheumatoid arthritis, compared with adalimumab.

Sarilumab Plus DMARDs: Effects on Glycemic Control in Comorbid RA and Diabetes

Sarilumab Plus DMARDs: Effects on Glycemic Control in Comorbid RA and Diabetes

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A combination of sarilumab and DMARDs administered for 24 weeks was shown to effectively reduce fasting glucose and glycosylated hemoglobin in patients with RA, with or without diabetes.

Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis

Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis

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Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.

Secukinumab Effectively Inhibits Radiographic Progression of PsA

Secukinumab Effectively Inhibits Radiographic Progression of PsA

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Regardless of dose, patients taking secukinumab were more likely to experience no radiographic progression compared with placebo.

Successful Biologics Tapering in Rheumatoid Arthritis Predicted by Younger Age, CRP Level

Successful Biologics Tapering in Rheumatoid Arthritis Predicted by Younger Age, CRP Level

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Factors may be predictive of successful tapering of biologics in patients with rheumatoid arthritis who are in remission.

EULAR/ACR Systemic Lupus Erythematosus Classification Criteria Update

EULAR/ACR Systemic Lupus Erythematosus Classification Criteria Update

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EULAR and ACR jointly funded and collaborated on creating a set of criteria that can be used to more accurately identify patients with SLE for inclusion in clinical trials.

Digital Health Coaching Program Improves Healthy Behaviors, Decreases RA Flares

Digital Health Coaching Program Improves Healthy Behaviors, Decreases RA Flares

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A behavior modification program can improve healthy behaviors and decrease symptoms of rheumatoid arthritis.

Tofacitinib Safety Comparable With Biologics

Tofacitinib Safety Comparable With Biologics

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The real-world rates of most adverse events in patients with psoriatic arthritis receiving several biologics may be comparable with those reported in phase 3 studies of tofacitinib.

Key Hemodynamic Differences Noted With Scleroderma-Associated PAH vs Idiopathic PAH

Key Hemodynamic Differences Noted With Scleroderma-Associated PAH vs Idiopathic PAH

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Patients with systemic sclerosis-associated pulmonary arterial hypertension display important differences in hemodynamic and pulmonary function parameters compared with patients with idiopathic PAH.

ACR 2017 Debates the Pros and Cons of Switching to Biosimilars

ACR 2017 Debates the Pros and Cons of Switching to Biosimilars

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The debate highlighted relevant data that should drive the decision to switch to biosimilars.

Depression Associated With Disease Activity in Early Rheumatoid Arthritis

Depression Associated With Disease Activity in Early Rheumatoid Arthritis

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Initial high disease activity in patients with early rheumatoid arthritis is associated with an increased risk for depression and persistent depression.

Temporary Methotrexate Discontinuation Improves Influenza Vaccine Immunogenicity in RA

Temporary Methotrexate Discontinuation Improves Influenza Vaccine Immunogenicity in RA

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Temporary methotrexate discontinuation after receiving seasonal influenza vaccination improves the immunogenicity of vaccination in patients with rheumatoid arthritis.

High BMI, Obesity Predict Worse Disease Outcomes in Axial Spondyloarthropathy

High BMI, Obesity Predict Worse Disease Outcomes in Axial Spondyloarthropathy

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Recognition of the negative consequences of being obese is vital to effectively managing axial spondyloarthropathy.

Wnt Pathway Inhibition Alleviates Symptoms of Knee Osteoarthritis

Wnt Pathway Inhibition Alleviates Symptoms of Knee Osteoarthritis

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Inhibition of the Wnt pathway with the small molecule SM04690 was shown to improve pain and maintain or improve radiographic outcomes in patients with knee osteoarthritis.

Obesity, Disease Activity Paradox Found in Systemic Lupus Erythematosus

Obesity, Disease Activity Paradox Found in Systemic Lupus Erythematosus

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Researchers studied how BMI changes would affect disease activity in systemic lupus erythematosus

Multibiomarker Screen Predicts Radiographic Progression in Rheumatoid Arthritis

Multibiomarker Screen Predicts Radiographic Progression in Rheumatoid Arthritis

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Data from 6 cohorts were used to evaluate and establish the relationship between multibiomarker disease activity score and radiographic progression risk.

Pregnancy Outcomes in SLE vs Other Connective Tissue, Inflammatory Rheumatic Conditions

Pregnancy Outcomes in SLE vs Other Connective Tissue, Inflammatory Rheumatic Conditions

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Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.

Anemia Associated With Radiographic Progression in Methotrexate-Naïve Patients

Anemia Associated With Radiographic Progression in Methotrexate-Naïve Patients

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In this post hoc analysis, researchers explored whether anemia was a predictor of radiographic progression in patients with RA who were treated with tofacitinib.

Obesity Leads to Poor Outcomes for Patients with Systemic Lupus Erythematosus

Obesity Leads to Poor Outcomes for Patients with Systemic Lupus Erythematosus

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The impact of excess adiposity in SLE has not been established, despite obesity being a common comorbidity in SLE.

Biologics Show Greater Response Rate After Secondary Response Failure to TNFi in RA

Biologics Show Greater Response Rate After Secondary Response Failure to TNFi in RA

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Criteria for determining whether a second TNFi or BDMA should be given to patients with secondary failure to TNFi requires further clinical clarification.

Childhood-Onset SLE Predicts Steroid Damage Over Time

Childhood-Onset SLE Predicts Steroid Damage Over Time

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Little is known about differences in long-term steroid toxicity between adults with cSLE and aSLE.

Long-Term Safety of Adalimumab in Immune-Related Diseases Analyzed

Long-Term Safety of Adalimumab in Immune-Related Diseases Analyzed

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Investigators sought to determine the long-term safety of adalimumab use in patients with arthritis and other immune-related diseases.

2017 ACR/ARHP Annual Meeting: What to Expect

2017 ACR/ARHP Annual Meeting: What to Expect

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Sessions at the 2017 ACR/ARHP meeting will include the annual "Great Debate," which will discuss the role of biosimilars.

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