Bone Mineral Density

Effect of Mediterranean Diet Plus Vitamin D3 on Bone Density in Osteoporosis

Effect of Mediterranean Diet Plus Vitamin D3 on Bone Density in Osteoporosis

By

Investigators examined the effect of consuming a Mediterranean-style diet for 1 year on inflammatory response and bone health in the elderly.

Empagliflozin Does Not Increase Fracture Risk in Type 2 Diabetes

Empagliflozin Does Not Increase Fracture Risk in Type 2 Diabetes

By

The risk for bone fractures was not increased in patients with type 2 diabetes using empagliflozin compared with placebo or glimepiride.

Serotonin Levels Predict Increased Risk for Hip Fracture, Nonvertebral Osteoporotic Fracture

Serotonin Levels Predict Increased Risk for Hip Fracture, Nonvertebral Osteoporotic Fracture

By

High levels of serotonin are predictive of an increased risk for hip fracture, nonvertebral osteoporotic fracture, and incident fractures in older men.

Romosozumab Followed by Denosumab Effective for BMD Increase in Postmenopausal Women

Romosozumab Followed by Denosumab Effective for BMD Increase in Postmenopausal Women

By

Romosozumab increased bone mineral density in postmenopausal women through increased bone formation and decreased bone resorption.

Examining Bone Microarchitecture, Strength in Older Men With Accelerated Bone Loss

Examining Bone Microarchitecture, Strength in Older Men With Accelerated Bone Loss

By

Men with accelerated bone loss have lower estimated bone strength, poorer trabecular microarchitecture, and thinner cortices compared with men without accelerated bone loss.

Effects of the 2 Types of Anorexia Nervosa on Bone Metabolism

Effects of the 2 Types of Anorexia Nervosa on Bone Metabolism

By

Investigators sought to determine whether both restrictive and purging types of anorexia nervosa effect bone metabolism.

Bone Mass and Microarchitecture Adversely Affected by Gastric Bypass Surgery

Bone Mass and Microarchitecture Adversely Affected by Gastric Bypass Surgery

By

Gastric bypass surgery can have damaging effects on bone mass as early as 6 months postoperatively.

Routine Vitamin D, Calcium Supplementation Not Associated With Fracture Reduction in Older Adults

Routine Vitamin D, Calcium Supplementation Not Associated With Fracture Reduction in Older Adults

By

Routine vitamin D and calcium supplementation in older adults is not supported for lowering the incidence of osteoporosis-related fractures.

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

By

Tocilizumab treatment for 2 years was shown to reduce levels of bone loss in patients with ACPA-positive RA.

Growth Hormone Therapy May Reduce Fracture Risk in Postmenopausal Women With Osteoporosis

Growth Hormone Therapy May Reduce Fracture Risk in Postmenopausal Women With Osteoporosis

By

Growth hormone therapy may reduce the risk for fracture in patients with osteoporosis.

Updated UK Clinical Guidelines for Osteoporosis Emphasize Risk Assessment and Prevention

Updated UK Clinical Guidelines for Osteoporosis Emphasize Risk Assessment and Prevention

By

The UK National Osteoporosis Guideline Group released updated guidelines for the prevention of fragility fracture in postmenopausal women and in men aged 50 years or older.

Low Hip BMD Associated With Higher HF Risk in Certain Patient Subgroups

Low Hip BMD Associated With Higher HF Risk in Certain Patient Subgroups

By

Total hip BMD was associated with heart failure risk in black and non-black men, with an interaction by race.

DXA Not Useful for Workup of Vertebral Compression Deformities With Normal BMD

DXA Not Useful for Workup of Vertebral Compression Deformities With Normal BMD

By

Researchers compared the efficacy of dual-energy x-ray absorptiometry with lateral x-ray in assessing vertebral fractures.

The Handoff: Your Week in Rheumatology News - 4/14/17

The Handoff: Your Week in Rheumatology News - 4/14/17

By

This week, a phase III trial for investigational drug voclosporin for lupus nephritis treatment was approved, prolonged insomnia may lead to less robust bone formation — causing osteoporosis and bone fractures — and researchers found that women who drink a moderate amount of alcohol daily have a reduced risk of developing systemic lupus erythmatosus.

Postmenopause Osteoporosis Drug Denosumab Demonstrates Long-term Safety

Postmenopause Osteoporosis Drug Denosumab Demonstrates Long-term Safety

By

Three-year fracture study examines the effects of osteoporosis drug denosumab on fractures, bone mineral density, and bone turnover markers in postmenopausal women with osteoporosis.

Anti-fracture Therapy Prevents Bone Loss in Women After Critical Illness

Anti-fracture Therapy Prevents Bone Loss in Women After Critical Illness

By

Prospective observational cohort study examines association between post-ICU administration of anti-fracture therapy or glucocorticoids and longitudinal changes in bone mineral density.

Testosterone Treatment Increases Bone Mineral Density and Strength in Older Men

Testosterone Treatment Increases Bone Mineral Density and Strength in Older Men

By

Testosterone treatments help improve volumetric bone mineral density and bone strength in elderly men with low testosterone.

Utility of Trabecular Bone Score in Assessing Bone Quality in Type 2 Diabetes

Utility of Trabecular Bone Score in Assessing Bone Quality in Type 2 Diabetes

By

The trabecular bone score may provides an acute, albeit indirect, measurement of bone quality in patients with type 2 diabetes.

Predicting Vertebral Fracture Risk After Bisphosphonate Drug Holiday

Predicting Vertebral Fracture Risk After Bisphosphonate Drug Holiday

By

Study examines the predictive value for vertebral fractures of bone mineral density and bone turnover markers after a 5-year drug holiday.

Bone Metabolism Risks Associated With Tenofovir for Hepatitis B Infection

Bone Metabolism Risks Associated With Tenofovir for Hepatitis B Infection

By

Long-term tenofovir treatment for hepatitis B infection is linked with abnormal phosphorus metabolism in a recent study.

VIDEO: Updated Clinical Trial Results for Abaloparatide

VIDEO: Updated Clinical Trial Results for Abaloparatide

By

Lorraine Fitzpatrick, MD, discusses updated results from the ACTIVE phase 3 clinical trial.

Postmenopausal Hormone Therapy Improves Bone Structure

Postmenopausal Hormone Therapy Improves Bone Structure

By

Higher Trabecular Bone Scores were found in postmenopausal women taking hormone replacement therapy compared with women who had never used hormone therapy.

Protectective Effects of DMARDs on Bone Loss

Protectective Effects of DMARDs on Bone Loss

By

DMARDs have been shown to be effective in halting progressive bone loss in rheumatoid arthritis.

Stimulant Use Linked to Low Lumbar, Femur BMD in Adolescents

Stimulant Use Linked to Low Lumbar, Femur BMD in Adolescents

By

Pediatric and adolescent patients who used stimulants to treat ADHD were found to have low bone density and bone mineral content.

Call to Action Issued to Address Ongoing Osteoporosis Treatment Crisis

Call to Action Issued to Address Ongoing Osteoporosis Treatment Crisis

By

Kenneth Saag, MD, president of the National Osteoporosis Foundation (NOF), co-chair of the National Bone Health Alliance, and Rheumatology Advisor advisory board member, reports on the recent changes that have led to the current state of osteoporosis treatment in the US.

Association Between Time Spent Sitting and BMD Investigated

Association Between Time Spent Sitting and BMD Investigated

By

Findings showing that sedentary time was not significantly linked to bone mineral density weaken the previous association between physical activity and bone mineral density.

Fracture Risk With ARBs, CCBs, ACE Inhibitors Compared

Fracture Risk With ARBs, CCBs, ACE Inhibitors Compared

By

The use of ARBs was associated with lower incidence of non-vertebral fractures than ACE inhibitors or CCBs.

Denosumab vs Risendronate for GC-Induced Osteoporosis

Denosumab vs Risendronate for GC-Induced Osteoporosis

By

Denosumab treatment led to significant increases in BMD at the lumbar spine and total hip at 12 months as compared to risedronate, both in patients receiving continuing glucocorticoid therapy and those just starting glucocorticoid therapy.

Bone Turnover Markers Used to Create New Bone Balance Index

Bone Turnover Markers Used to Create New Bone Balance Index

To better predict bone loss during the menopausal transition, researchers created the bone balance index using bone turnover markers to measure net bone formation.

Are Changes in Serial DXA Scans Reliable Indicators of Fracture Risk?

Are Changes in Serial DXA Scans Reliable Indicators of Fracture Risk?

Interval changes in bone mineral density (BMD) detected by dual-energy x-ray absorptiometry (DXA) are associated with fracture risk in women starting osteoporosis treatment

Sign Up for Free e-newsletters