Connective Tissue Disease

Muscle MRI as Complementary Diagnostic Tool for Juvenile Dermatomyositis

Muscle MRI as Complementary Diagnostic Tool for Juvenile Dermatomyositis

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Muscle magnetic resonance imaging may complement a physician's objective assessment in juvenile dermatomyositis, although negative MRI findings should not preclude treatment continuation.

Understanding the Natural History of Ehlers-Danlos Syndrome-Hypermobility Type

Understanding the Natural History of Ehlers-Danlos Syndrome-Hypermobility Type

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A better understanding of the natural progression of this disease would allow earlier detection in children at high risk for functional decline.

HPV Vaccine Does Not Increase Autoimmune Disease Risk

HPV Vaccine Does Not Increase Autoimmune Disease Risk

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Researchers used registry data to evaluate the risk of autoimmune diseases over 6.5 years after exposure to HPV vaccines in adolescent and young adult women.

Juvenile Dermatomyositis Management Recommendations Established

Juvenile Dermatomyositis Management Recommendations Established

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A European committee of pediatric rheumatology experts has provided the first consensus-based recommendations for clinical management of juvenile dermatomyositis.

Dual Therapy Improves Treatment Response in Connective Tissue Disease-Associated Pulmonary Hypertension

Dual Therapy Improves Treatment Response in Connective Tissue Disease-Associated Pulmonary Hypertension

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Post hoc study subgroup analysis shows combination ambrisentan plus tadalafil therapy improves treatment response in patients with connective tissue disease-associated pulmonary arterial hypertension.

EULAR/PReS Standards for Transitional Care of Juvenile-Onset Rheumatic Diseases

EULAR/PReS Standards for Transitional Care of Juvenile-Onset Rheumatic Diseases

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Panel advises that up to 50% of young patients with juvenile-onset rheumatic diseases fail to successfully transition to adult rheumatology services.

Dose-Response Relationship Between Glucocorticoids and <i>S. aureus</i> Bacteremia Risk

Dose-Response Relationship Between Glucocorticoids and S. aureus Bacteremia Risk

Data from a population-based case control study found that systemic glucocorticoid use was associated with increased risk of S. aureus bacteremia (CA-SAB), with a clear dose-response relationship.

RHC Parameters Prognostic of Survival in CTD-ILD

RHC Parameters Prognostic of Survival in CTD-ILD

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Mild elevations in MPAP were commonly found in newly diagnosed CTD-ILD, regardless of the background CTD, in this cohort of patients.

Predictors of Skin Fibrosis Regression in Diffuse Cutaneous Systemic Sclerosis

Predictors of Skin Fibrosis Regression in Diffuse Cutaneous Systemic Sclerosis

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Regression of skin fibrosis is a feature of the natural history of dcSSc. However, the pattern of regression can be quite heterogeneous despite improvements in predicting progression.

Anti-U1 RNP Positivity Associated With Increased Survival in CTD-Associated PAH

Anti-U1 RNP Positivity Associated With Increased Survival in CTD-Associated PAH

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Hemodynamic data and survival were compared in a subgroup of patients with pulmonary arterial hypertension in the setting of connective tissue disease.

Incidence of ASCVD  Increased in African Americans and Young Adults With Inflammatory CTD

Incidence of ASCVD Increased in African Americans and Young Adults With Inflammatory CTD

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CTD is associated with higher prevalence of atherosclerotic cardiovascular disease in African Americans and in young adults.

Quantifying Heritability and Genetic Sharing of Pediatric Autoimmune Disorders

Quantifying Heritability and Genetic Sharing of Pediatric Autoimmune Disorders

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Researchers quantified the heritability and genetic sharing for 9 pediatric autoimmune disorders.

Tocilizumab Potential Treatment Option for Polymyalgia Rheumatica

Tocilizumab Potential Treatment Option for Polymyalgia Rheumatica

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Recent data show that tocilizumab is associated with improved quality of life without aggressive steroid treatment in patients with polymyalgia rheumatica.

Increased Risk of Autoimmune Disorders Seen in Survivors of Cancer in Childhood

Increased Risk of Autoimmune Disorders Seen in Survivors of Cancer in Childhood

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Survivors of cancer in childhood are more susceptible to autoimmune disorders.

IL-6, IL-17 Accurate Biomarkers for Systemic Lupus Erythematosus Disease Activity

IL-6, IL-17 Accurate Biomarkers for Systemic Lupus Erythematosus Disease Activity

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Systemic lupus erythematosus disease activity can be assessed using IL-6 and IL-17 baseline serum levels as biomarkers.

Promising Treatment for Scleroderma-Related Interstitial Lung Disease

Promising Treatment for Scleroderma-Related Interstitial Lung Disease

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Cyclophosphamide and mycophenolate mofetil efficacious for scleroderma-related lung disease, according to trial data reported at ACR/ARHP 2015.

Pain Coping and Catastrophizing in Systemic Lupus Erythematosus

Pain Coping and Catastrophizing in Systemic Lupus Erythematosus

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Researchers identify pain factors to improve care for patients with lupus.

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