Fibromyalgia

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The Role of Neurogenic Inflammation in Fibromyalgia Pathophysiology

The Role of Neurogenic Inflammation in Fibromyalgia Pathophysiology

Geoffrey Littlejohn, MD, provides a clinical perspective on the pathophysiology of fibromyalgia and the role of neurogenic inflammation in the disease process.

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Operant Learning May Provide More Benefits Than Energy Conservation in Fibromyalgia

Operant Learning May Provide More Benefits Than Energy Conservation in Fibromyalgia

Operant learning may provide additional benefits compared with energy conservation in patients with fibromyalgia syndrome.

Transcutaneous Electrical Nerve Stimulation Reduces Pain, Fatigue in Fibromyalgia

Transcutaneous Electrical Nerve Stimulation Reduces Pain, Fatigue in Fibromyalgia

Transcutaneous electrical nerve stimulation administered during physical activity may effectively alleviate fibromyalgia-associated pain, fatigue, and disease impact in women.

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

Internet-Delivered Exposure Therapy Cost-Effective for Patients With Fibromyalgia

In a randomized control trial, researchers found that internet-delivered exposure therapy was more cost-effective for patients with fibromyalgia than a waitlist control, which did not involve any treatment during the experimental phase of the study.

Outpatient Engagement May Lower Suicide Attempts in Patients With Fibromyalgia

Outpatient Engagement May Lower Suicide Attempts in Patients With Fibromyalgia

Researchers identified risk factors for suicidal ideation and suicide attempts in patients with fibromyalgia.

Allopurinol Demonstrates No Analgesic Effect for Fibromyalgia Pain

Allopurinol Demonstrates No Analgesic Effect for Fibromyalgia Pain

Allopurinol did not provide pain relief for patients with fibromyalgia pain over the course of 30 days.

Trial Evaluating BCG Vaccine for Fibromyalgia Given Green Light by FDA

Trial Evaluating BCG Vaccine for Fibromyalgia Given Green Light by FDA

The investigators hope that the BCG vaccine can increase anti-inflammatory cytokines, which are deficient in patients with fibromyalgia.

Presence of Fibromyalgia May Worsen Migraine Disability, Depressive Symptoms

Presence of Fibromyalgia May Worsen Migraine Disability, Depressive Symptoms

Patients with comorbid fibromyalgia and migraine vs migraine alone may experience more depressive symptoms, greater headache intensity, and be more likely to have severe headache-related disability.

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis

Meeting the criteria for fibromyalgia had a modest effect on disease activity and did not influence the response to TNFi therapy.

Endocannabinoids May Be Elevated in Women With Fibromyalgia

Endocannabinoids May Be Elevated in Women With Fibromyalgia

Women with fibromyalgia were found to have elevated levels of endocannabinoidome lipid mediators.

Mirtazapine for Fibromyalgia: An Effective Treatment Option?

Mirtazapine for Fibromyalgia: An Effective Treatment Option?

Mirtazapine is a central alpha-2 antagonist currently FDA-approved for the treatment of major depressive disorder.

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