Gout

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Gout, Urate-Lowering Therapy Not Associated With Risk for Fragility Fracture

Gout, Urate-Lowering Therapy Not Associated With Risk for Fragility Fracture

The use of urate-lowering therapy in patients with gout had neither beneficial nor adverse effects on long-term fracture risk.

Pegloticase Retreatment Effective for Gout After Gap in Therapy

Pegloticase Retreatment Effective for Gout After Gap in Therapy

The study authors retrospectively analyzed the charts of 4 chronic gout patients from a practice-based rheumatology clinic.

Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?

Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?

Ethnicity and hypertension have an association with incident gout that is not fully explained by differences in serum urate.

Crystal-Proven Gout, Gout Severity Factors Linked to Cardiovascular Disease

Crystal-Proven Gout, Gout Severity Factors Linked to Cardiovascular Disease

Investigators sought to examine the prevalence of CVD in patients with crystal-proven gout compared with control patients with arthritis.

Racial Variations Linked to Risk for Allopurinol-Associated Adverse Reactions

Racial Variations Linked to Risk for Allopurinol-Associated Adverse Reactions

Researchers found that the overall risk for hospitalization due to allopurinol-associated severe cutaneous adverse reactions is rare.

Corticosteroids May Be an Effective Alternative to NSAIDs in Acute Gout Pain

Corticosteroids May Be an Effective Alternative to NSAIDs in Acute Gout Pain

Corticosteroids appear to be a reasonable alternative to NSAIDs for the treatment of acute pain as a result of gout.

Fenofibrate Decreases Plasma Uric Acid Concentration, Gout Events in T2D

Fenofibrate Decreases Plasma Uric Acid Concentration, Gout Events in T2D

Fenofibrate may be a valuable adjunct therapy in type 2 diabetes to reduce the burden of gout.

Allopurinol Dose Escalation May Not Improve Survival in Patients With Gout

Allopurinol Dose Escalation May Not Improve Survival in Patients With Gout

Investigators sought to determine whether allopurinol dose escalation is associated with all-cause mortality.

Ultrasound Reliably Identifies Calcium Pyrophosphate Deposition Disease

Ultrasound Reliably Identifies Calcium Pyrophosphate Deposition Disease

Ultrasound is a reliable diagnostic tool for identifying calcium pyrophosphate deposition disease.

Febuxostat vs Allopurinol Evaluated in Patients With Gout, CVD

Febuxostat vs Allopurinol Evaluated in Patients With Gout, CVD

Febuxostat is noninferior to allopurinol for rates of adverse CV events but is associated with higher all-cause and CV mortality in patients with gout and CVD.

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