Gout

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Elevated Serum Uric Acid Levels May Increase Risk for Dementia in Older Adults

Elevated Serum Uric Acid Levels May Increase Risk for Dementia in Older Adults

Risk for dementia may be increased with high serum uric acid levels in elderly individuals.

Higher Monosodium Urate Crystal Depositions With Greater Disease Severity in Allopurinol-Treated Gout

Higher Monosodium Urate Crystal Depositions With Greater Disease Severity in Allopurinol-Treated Gout

In patients with gout who are treated with allopurinol, monosodium urate crystal depositions are higher with evidence of greater disease severity.

Febuxostat Lowers Blood Pressure in Patients With Hyperuricemia and Hypertension

Febuxostat Lowers Blood Pressure in Patients With Hyperuricemia and Hypertension

Febuxostat may lower blood pressure in patients with hyperuricemia, hypertension, and normal renal function.

Allopurinol Use May Lower Risk for Peripheral Arterial Disease

Allopurinol Use May Lower Risk for Peripheral Arterial Disease

New allopurinol use was associated with a reduced risk of incident peripheral arterial disease.

Gout Flares Reduced by Febuxostat Increase Plus Low-Dose Colchicine

Gout Flares Reduced by Febuxostat Increase Plus Low-Dose Colchicine

A stepwise dose increase in febuxostat plus low-dose colchicine prophylaxis was effective in the reduction of gout flares compared with febuxostat alone.

Metoprolol Elevates Serum Uric Acid and Gout Risk in African Americans

Metoprolol Elevates Serum Uric Acid and Gout Risk in African Americans

As the risk of developing gout is high in patients with hypertension, management of serum uric acid levels may improve patient outcomes.

Gout Increases Incident Stroke Risk by the Same Magnitude as Diabetes

Gout Increases Incident Stroke Risk by the Same Magnitude as Diabetes

A recent study assessed whether gout is a cardiovascular risk equivalent for stroke and myocardial infarction, similar to diabetes.

FDA Alert: Febuxostat May Increase Risk of Heart-Related Adverse Events, Death

FDA Alert: Febuxostat May Increase Risk of Heart-Related Adverse Events, Death

Gout medication febuxostat (Uloric) was associated with an increased risk of heart-related death and death from all causes.

Online Consultation System Benefits Rheumatic Disease Management

Online Consultation System Benefits Rheumatic Disease Management

The SSDM series of applications is cost-effective for patients of rheumatologists.

High-Dose Lesinurad Deemed Unsuitable as Monotherapy for Gout

High-Dose Lesinurad Deemed Unsuitable as Monotherapy for Gout

Despite rapidly lowering serum uric acid levels, lesinurad cannot be recommended alone at 400 mg per day, due to substantial adverse events.

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