In-Depth Focus From ACR 2017 Spondyloarthritis

Inflammation of Sacroiliac Joint in Axial Spondyloarthritis vs Healthy Participants

Inflammation of Sacroiliac Joint in Axial Spondyloarthritis vs Healthy Participants

By

Inflammation shown on MRI of the sacroiliac joint (MRI-SI) is prevalent in axSpA (±30%), but the specificity is not well known.

Abatacept Improves Outcomes in Patients With Active Psoriatic Arthritis

Abatacept Improves Outcomes in Patients With Active Psoriatic Arthritis

By

Administration of abatacept may improve patient-reported outcomes in individuals with active psoriatic arthritis and elevated levels of C-reactive protein, irrespective of tumor necrosis factor inhibitor treatment history.

Role of Gut Microbiota, Host Genetics in Reactive Arthritis

Role of Gut Microbiota, Host Genetics in Reactive Arthritis

By

Researchers found that HLA status was associated with gut microbiota diversity.

Draft Psoriatic Arthritis Guideline Presented at ACR 2017

Draft Psoriatic Arthritis Guideline Presented at ACR 2017

By

The guideline includes recommendations for treating adult patients with active psoriatic arthritis.

Secukinumab Effective for Inhibiting Radiographic Progression in PsA

Secukinumab Effective for Inhibiting Radiographic Progression in PsA

By

Regardless of dose, patients taking secukinumab were more likely to experience no radiographic progression compared with placebo.

TNF Inhibitors Decrease Extraarticular Manifestations in Ankylosing Spondylitis

TNF Inhibitors Decrease Extraarticular Manifestations in Ankylosing Spondylitis

By

Treatment with TNF inhibitors has led to improvement in physical function and quality of life in patients with ankylosing spondylitis.

Tofacitinib Improves Patient-Reported Outcomes for Active Psoriatic Arthritis

Tofacitinib Improves Patient-Reported Outcomes for Active Psoriatic Arthritis

By

Results from phase 3 trials OPAL Broaden (NCT01877668) and OPAL Beyond (NCT01882439) presented at the American College of Rheumatology 2017 in San Diego, California.

Local Inflammation Predicts Structural Damage in Axial Spondyloarthritis

Local Inflammation Predicts Structural Damage in Axial Spondyloarthritis

By

Researchers recruited patients with recent onset axial spondyloarthritis and conducted MRI of the spine or MRI of the sacroiliac joints at baseline, 2 years, and 5 years.

Therapeutic Goal Achievement Independent of Cardiovascular Risk in Psoriatic Arthritis

Therapeutic Goal Achievement Independent of Cardiovascular Risk in Psoriatic Arthritis

By

With the exception of sedentary lifestyle, cardiovascular risk factors were not found to impact the likelihood of achieving minimal disease activity among patients with psoriatic arthritis.

Higher Prevalence of Depression, ADHD Observed Among Women With Psoriatic Arthritis

Higher Prevalence of Depression, ADHD Observed Among Women With Psoriatic Arthritis

By

Researchers observed a higher prevalence of psychiatric disorders among female patients with psoriatic arthritis.

Sign Up for Free e-newsletters