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Juvenile Dermatomyositis Management Recommendations Established

Juvenile Dermatomyositis Management Recommendations Established

A European committee of pediatric rheumatology experts has provided the first consensus-based recommendations for clinical management of juvenile dermatomyositis.

Polymyositis May Increase Risk of Amyotrophic Lateral Sclerosis

Polymyositis May Increase Risk of Amyotrophic Lateral Sclerosis

The relationship between PM and ALS could indicate a common pathophysiology.

Increased Incidence of LV Diastolic Dysfunction in PM/DM

Increased Incidence of LV Diastolic Dysfunction in PM/DM

Patients with PM or DM had an increased prevalence of cardiac abnormalities, most commonly left ventricular diastolic dysfunction, compared with healthy controls.

Autoantibodies Prognostic of Dysphagia in Dermatomyositis

Autoantibodies Prognostic of Dysphagia in Dermatomyositis

Recognizing dysphagia is important because it is associated with various clinical features that lead to an impaired quality of life and poor prognosis.

Exercise May Reduce Impairment in Inflammatory Myopathies

Exercise May Reduce Impairment in Inflammatory Myopathies

Five randomized controlled trials including adult patients with polymyositis and dermatomyositis (DM) and additional open studies have demonstrated reduced impairment and activity limitation as well as improved quality of life. Exercise can improve muscle aerobic capacity as shown by increased mitochondrial enzyme activity. These data suggest that intensive aerobic exercise and resistance training could reduce disease activity and inflammation and improve muscle metabolism.

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