Use of Opioid Prior to TKA Associated With Worse Post-Op Pain

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The team found that mean preoperative Pain Catastrophizing Scale scores were greater among opioid users.
The team found that mean preoperative Pain Catastrophizing Scale scores were greater among opioid users.

HealthDay News — Patients taking opioids before total knee arthroplasty (TKA) may have greater pain after the procedure, according to a study published in the May 17 issue of the Journal of Bone & Joint Surgery.

The research included 156 patients who underwent TKA. Their average age was 66. Of those patients, 23% received at least 1 opioid prescription before their surgery.

The team found that mean preoperative Pain Catastrophizing Scale scores were greater among opioid users versus non-users (15.5 vs 10.7 points; P =.006). In adjusted analyses, the researchers found that the opioid group had a mean 6-month reduction in Western Ontario and McMaster Universities Osteoarthritis Index score of 27.0 points, compared with 33.6 points in the non-opioid group (P =.008).

"Patients who used opioids prior to TKA obtained less pain relief from the operation," the authors wrote. "Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA."

Reference 

Smith S, Bido J, Collins J, et al; Impact of Preoperative Opioid Use on Total Knee Arthroplasty Outcomes. JB&JS. May 17, 2017; 99(10)803-808. doi:10.2106/JBJS.16.01200

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