Noninferiority of Celecoxib to Ibuprofen & Naproxen for CV Events: Understanding Implications of the PRECISION Trial

Numerically fewer Antiplatelet Trialists Collaboration composite outcome events occurred with celecoxib treatment than with naproxen and ibuprofen. PRECISION lead investigator Dr Steven Nissen discusses clinical ...

The Impact of Obesity on Arthritis Outcomes

Obesity may affect risk of developing osteoarthritis and rheumatoid arthritis, and it has been linked with increased disease activity and adverse clinical outcomes.

Review of the Evidence Behind Platelet-Rich Plasma Therapy

Platelet-rich plasma (PRP) therapy is being used by clinicians to treat patients with symptomatic or post-traumatic osteoarthritis. While basic science and preclinical data support some ...

Conservative Management Options for Osteoarthritis

Conservative treatment options include weight loss, physical therapy, activity modification, drugs, orthotics, and intra-articular injections.

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Modified Exercise Improves Physical Function in Knee Osteoarthritis

Modified Exercise Improves Physical Function in Knee Osteoarthritis

Patients in the intervention group saw improvements in WOMAC and 6MWT scores after participating in adapted exercise programs.

Mobility Barriers' Impact on Daily Life of Patients With Knee Osteoarthritis

Mobility Barriers' Impact on Daily Life of Patients With Knee Osteoarthritis

Barriers to mobility within communities may lead to "participation restriction" in elderly with knee osteoarthritis.

Use of Opioid Prior to TKA Associated With Worse Post-Op Pain

Use of Opioid Prior to TKA Associated With Worse Post-Op Pain

Researchers suggest that limiting opioid prescriptions might optimize benefits of TKA.

Chondroitin Sulfate Effective for Knee Osteoarthritis

Chondroitin Sulfate Effective for Knee Osteoarthritis

Prescription-grade chondroitin sulfate is as efficacious as celecoxib in reducing pain and improving function in patients with knee osteoarthritis.

Decreased Rate of Hip Fracture in Patients With End-Stage Renal Disease

Decreased Rate of Hip Fracture in Patients With End-Stage Renal Disease

From 2003 to 2011 there was a decrease in hip fracture rate and in-hospital mortality after hip fracture.

Ultrasound More Accurate Diagnosis of Hand Osteoarthritis Than Radiography

Ultrasound More Accurate Diagnosis of Hand Osteoarthritis Than Radiography

Ultrasound examination of the hands can facilitate the diagnosis of hand osteoarthritis in patients who do not fulfill ACR criteria.

Guidelines for Peri-Op Care in Rheumatic Disease

Guidelines for Peri-Op Care in Rheumatic Disease

These guidelines address the use of antirheumatic drugs for adults with RA, SpA, JIA, and SLE undergoing THA or TKA.

Intramuscular Corticosteroid Injection Reduces Hip Pain in OA

Intramuscular Corticosteroid Injection Reduces Hip Pain in OA

In patients with osteoarthritis, corticosteroid injection was associated with significant hip pain reduction.

Knee Osteoarthritis Treatment: Chondroitin As Effective as Celecoxib

Knee Osteoarthritis Treatment: Chondroitin As Effective as Celecoxib

For symp¬tomatic OA, CONCEPT was the first trial of chondroitin to be conducted in compliance with EMA recommendations for investigating the efficacy of agents.

Long-Term Type 1 Diabetes Not Linked to Hand Osteoarthritis

Long-Term Type 1 Diabetes Not Linked to Hand Osteoarthritis

However, while not associated with hand OA, long-term type 1 diabetes is associated with hand pain, disability, and stiffness.