Osteoarthritis

Exploring the Association Between Quadriceps Strength, Functional Outcomes in Knee Osteoarthritis

Exploring the Association Between Quadriceps Strength, Functional Outcomes in Knee Osteoarthritis

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Researchers assessed quadriceps strength and physical function in individuals with knee osteoarthritis.

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

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Replacing at least 10 minutes a day of time spent sedentary, asleep, or in light physical activity with moderate physical activity may be associated with significant reductions in bodily pain interference and knee pain in adults at risk for osteoarthritis knee pain.

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

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Individuals using statins over 5 years and those using atorvastatin reported a lower risk for future osteoarthritis-related knee pain.

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

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Hyaluronic acid therapy may be more effective when supplemented with intra-articular platelet-rich plasma injections vs alone in treating primary knee osteoarthritis.

Extensive Effusion-Synovitis Linked to Progression of Cartilage Damage in OA With Meniscal Tear

Extensive Effusion-Synovitis Linked to Progression of Cartilage Damage in OA With Meniscal Tear

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Persistence of extensive effusion-synovitis over time was associated with the greatest risk for cartilage damage progression.

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

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The combined effects of pain with insomnia and pain with depression increased diverse types of health care use.

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

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Treatment strategies for late acute prosthetic joint infections should be individualized according to patients' age, comorbidities, clinical presentation, and microorganism causing the infection.

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

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A decrease of pain and a decrease of dynamic knee instability mediated the effect of wearing a soft knee brace on reduction of activity limitations.

Opioid Use in Osteoarthritis Linked to Worse Pain Interference, Functioning

Opioid Use in Osteoarthritis Linked to Worse Pain Interference, Functioning

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In patients with osteoarthritis, chronic pain is a primary symptom that may limit daily activities and impair function.

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

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Researchers examined the correlation between knee pain and radiographic features of osteoarthritis.

EULAR Releases 2018 Recommendations for the Management of Hand Osteoarthritis

EULAR Releases 2018 Recommendations for the Management of Hand Osteoarthritis

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EULAR has released updated guidelines for the management of hand osteoarthritis.

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

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Bilateral hip or knee osteoarthritis was significantly associated with a 16% to 25% increased risk for incident diabetes.

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

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Buckling of the hip joint, also referred to as "giving way," and hip injuries may be associated with hip pain worsening in patients with symptomatic hip osteoarthritis.

Exposure to Oral Osteoarthritis Therapies Not Linked to Increased Risk for Knee Replacement

Exposure to Oral Osteoarthritis Therapies Not Linked to Increased Risk for Knee Replacement

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The main risk factors leading to knee replacement surgery in patients with osteoarthritis include disease severity, symptoms, and high BMI.

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

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Change in pain and physical function score from baseline were chosen as the co-primary endpoints.

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

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The reliability of retrospective and daily pain measurements was comparable among patients with hip osteoarthritis, except in individuals with severe intermittent pain for whom retrospective measurements may be less reliable.

Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data

Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data

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The use of accelerometry data has led to the discovery of performance phenotypes of lumbar spinal stenosis and osteoarthritis.

Revision Rates for Arthritis-Related Hip Replacement Down

Revision Rates for Arthritis-Related Hip Replacement Down

Use of cross-linked polyethylene has significantly reduced the revision rate following total hip arthroplasty for osteoarthritis.

Knee Load Associated With Increased Walking Pain in Osteoarthritis

Knee Load Associated With Increased Walking Pain in Osteoarthritis

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Researchers examine the association between the knee adduction moment and increased knee pain during walking in patients with knee osteoarthritis.

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

Rates of Knee, Hip Arthroplasty Increasing Among Patients With Ankylosing Spondylitis

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Researchers observed increased rates of both knee and hip arthroplasties in older patients with ankylosing spondylitis.

Antirheumatic Medication Management for Orthopedic Surgery: An Interdisciplinary Perspective

Antirheumatic Medication Management for Orthopedic Surgery: An Interdisciplinary Perspective

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A rheumatologist and orthopedic surgeon provide an interdisciplinary perspective on the perioperative management of antirheumatic medications in patients undergoing elective orthopedic surgery.

Knee Joint Hypermobility May Be Linked to OA Foot, Ankle Symptoms

Knee Joint Hypermobility May Be Linked to OA Foot, Ankle Symptoms

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Researchers examine the relationship of joint hypermobility with osteoarthritis and symptoms at the foot or ankle.

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

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Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.

Walking Disability Associated With Arterial Stiffness in Osteoarthritis

Walking Disability Associated With Arterial Stiffness in Osteoarthritis

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Six-minute walking distance was significantly associated with arterial stiffness in individuals with osteoarthritis.

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

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Pfizer and Lilly announced positive results from a study evaluating tanezumab, an investigational humanized monoclonal antibody, for the treatment of OA pain.

Neuropathic Symptoms Worsen Quality of Life, Function in Hip, Knee Osteoarthritis

Neuropathic Symptoms Worsen Quality of Life, Function in Hip, Knee Osteoarthritis

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Neuropathic-like symptoms may affect pain-related quality of life ratings and function in patients with hip and knee osteoarthritis, respectively.

Risk for Knee Osteoarthritis in Adolescent Men Predicted in Modified Nottingham Model

Risk for Knee Osteoarthritis in Adolescent Men Predicted in Modified Nottingham Model

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Diagnostic prediction modeling for knee osteoarthritis in adolescent men helps calculate the individual and population risk of developing knee osteoarthritis over 40 years.

Increased Physical Activity Improves Mobility After Joint Replacement in Older Women

Increased Physical Activity Improves Mobility After Joint Replacement in Older Women

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Women with osteoarthritis who reported lower physical activity levels before total joint replacement were more likely to experience mobility limitations in late life.

Statin Initiation Not Associated With Incident Hand Osteoarthritis

Statin Initiation Not Associated With Incident Hand Osteoarthritis

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Researchers observed no association between statin initiation and incident hand osteoarthritis.

Slower Walking Speed Linked to Increased BML in Accelerated Knee Osteoarthritis

Slower Walking Speed Linked to Increased BML in Accelerated Knee Osteoarthritis

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Changes in the 20-meter walking test were associated with worsening in bone marrow lesions and effusion volume in adults who developed accelerated knee OA.

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