Osteoporosis

Denosumab Increases Bone Mineral Density in Women With Primary Hyperparathyroidism

Denosumab Increases Bone Mineral Density in Women With Primary Hyperparathyroidism

By

Treatment with denosumab may increase bone mineral density in older women with primary hyperparathyroidism-related osteoporosis.

Alogliptin May Be Associated With Lower Fracture Risk Compared With Linagliptin, Saxagliptin

Alogliptin May Be Associated With Lower Fracture Risk Compared With Linagliptin, Saxagliptin

By

Seventy-five randomized controlled trials were included in a meta-analysis comparing DDP-4 inhibitors with placebo and other diabetes medications.

Routine Vitamin D, Calcium Supplementation Not Associated With Fracture Reduction in Older Adults

Routine Vitamin D, Calcium Supplementation Not Associated With Fracture Reduction in Older Adults

By

Routine vitamin D and calcium supplementation in older adults is not supported for lowering the incidence of osteoporosis-related fractures.

Physical Activity Not Associated With Reduced Frailty Risk Among Sedentary, Older Adults

Physical Activity Not Associated With Reduced Frailty Risk Among Sedentary, Older Adults

Among older adults with functional limitations, a long-term physical activity program was not associated with reduced frailty risk.

Hip Fracture Risk Reduced With Certain Dairy Products, Fruits, Vegetables

Hip Fracture Risk Reduced With Certain Dairy Products, Fruits, Vegetables

Lower rates for hip fractures in women are linked to high intake of fermented milk products, along with fruits and vegetables.

Assessment of Risk for Venous Thromboembolism With Osteoporosis-Prevention Agents

Assessment of Risk for Venous Thromboembolism With Osteoporosis-Prevention Agents

By

The risk for venous thromboembolism among strontium ranelate, denosumab, teriparatide, alendronate, and other bisphosphonates was evaluated by investigators.

Delayed Hip Fracture Surgery Linked to Higher Mortality and Complications

Delayed Hip Fracture Surgery Linked to Higher Mortality and Complications

By

Hip fracture repair was linked to higher rates of 30-day mortality and post-operative complications when time between hospital arrival and surgery exceeded 24 hours.

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

Tocilizumab Reduces Bone Loss in ACPA-Positive Rheumatoid Arthritis

By

Tocilizumab treatment for 2 years was shown to reduce levels of bone loss in patients with ACPA-positive RA.

Regional Nerve Block May Reduce Pain, Time to Mobilization After Hip Fracture

Regional Nerve Block May Reduce Pain, Time to Mobilization After Hip Fracture

By

In patients with hip fractures, the use of a regional nerve block may provide pain relief, and decrease the risk for pneumonia.

Caffeine Intake May Increase Risk of Hip Fracture in Women

Caffeine Intake May Increase Risk of Hip Fracture in Women

By

Caffeine intake among women older than 50 may have a small association with a decrease in BMD, and may increase risk of hip fractures.

Bone Mineral Density Loss and Insulin Use in Women With Type 2 Diabetes

Bone Mineral Density Loss and Insulin Use in Women With Type 2 Diabetes

By

Rapid loss of bone density is linked with the use of insulin for T2D.

Reduced Fracture Risk With Abaloparatide, Alendronate in Postmenopausal Women

Reduced Fracture Risk With Abaloparatide, Alendronate in Postmenopausal Women

This suggests to us that, as is the standard now, when we use an anabolic agent, we can add in an antiresorptive such as alendronate, and see continued sustained reduction in fracture risk.

Growth Hormone Therapy May Reduce Fracture Risk in Postmenopausal Women With Osteoporosis

Growth Hormone Therapy May Reduce Fracture Risk in Postmenopausal Women With Osteoporosis

By

Growth hormone therapy may reduce the risk for fracture in patients with osteoporosis.

Adipose Tissue Associated With Bone Strength in Children, Adolescents

Adipose Tissue Associated With Bone Strength in Children, Adolescents

By

Greater visceral and/or subcutaneous adiposity may have an important role in bone growth during adolescence.

Lower Risk of New Fractures With Teriparatide Compared With Risedronate in Osteoporosis

Lower Risk of New Fractures With Teriparatide Compared With Risedronate in Osteoporosis

By

Investigators evaluated the efficacy of teriparatide vs risedronate in preventing clinical and vertebral fracture in post-menopausal women with existing vertebral fractures.

USPSTF Updates Osteoporosis Screening Recommendations for Fracture Prevention

USPSTF Updates Osteoporosis Screening Recommendations for Fracture Prevention

All women 65, high-risk postmenopausal women 65 should undergo bone measurement testing.

Romosozumab Decreases Fracture Risk in Women With Osteoporosis Taking Alendronate

Romosozumab Decreases Fracture Risk in Women With Osteoporosis Taking Alendronate

By

In postmenopausal women at high risk for fracture, treatment with romosozumab for 12 months, followed by alendronate, was associated with significantly fewer hip fractures than treatment with alendronate alone.

Femoral Neck Bone Loss in Males Protected by High Dietary Fiber

Femoral Neck Bone Loss in Males Protected by High Dietary Fiber

Higher dietary fiber and fruit fiber is protective against bone loss at the femoral neck in men.

Vertebral Fracture Assessment vs Conventional Spine Radiography

Vertebral Fracture Assessment vs Conventional Spine Radiography

By

The use of vertebral fracture assessment has shown adequate performance for the detection of vertebral fractures.

Zoledronate Shows Prolonged Antiresorptive Activity in Postmenopausal Women With Osteopenia

Zoledronate Shows Prolonged Antiresorptive Activity in Postmenopausal Women With Osteopenia

By

Prolonged antiresorptive activity of ≥3 years has been associated with single zoledronate doses between 1 and 5 mg in postmenopausal women with osteopenia.

Incidence of New Fractures Reduced With Abaloparatide Followed by Alendronate

Incidence of New Fractures Reduced With Abaloparatide Followed by Alendronate

By

Tymlos is approved to treat postmenopausal women with osteoporosis at high risk for fracture.

Incident Radiographic Vertebral Fractures Associated with Back Pain in Older Men

Incident Radiographic Vertebral Fractures Associated with Back Pain in Older Men

Clinically undiagnossed radiographic VFs are linked to increased back pain symptoms.

Osteoporotic Fractures, Diabetes Complications Similarly Affect QoL

Osteoporotic Fractures, Diabetes Complications Similarly Affect QoL

Quality of life is similarly impacted by osteoporotic fractures and complications of diabetes.

BMD in Menopause Improved With OSA-Related Hypoxia

BMD in Menopause Improved With OSA-Related Hypoxia

By

The risk of bone health decline in menopausal women is decreased by intermittent hypoxia in OSA.

Hypoxia in OSA Lowers Risk of Bone Health Decline in Menopausal Women

Hypoxia in OSA Lowers Risk of Bone Health Decline in Menopausal Women

By

Risk of bone health decline in menopausal women is decreased by intermittent hypoxia in OSA.

Do Depression, Anxiety Affect BMD in Anorexia?

Do Depression, Anxiety Affect BMD in Anorexia?

By

Anxiety and depression are associated with low BMD in anorexia patients.

Relationship of BMD and Physical Activity in Class III Obesity

Relationship of BMD and Physical Activity in Class III Obesity

By

In people with class III obesity, variance in femoral neck BMD can be determined by time spent doing light physical activity.

Prediction of Fractures and CV Events With Serum Osteoprotegerin Levels

Prediction of Fractures and CV Events With Serum Osteoprotegerin Levels

By

Following adjustment, fracture risk was highest among patients in the lowest osteoprotegerin levels.

No Association Between Opioid Intake and Patient Satisfaction After Ankle Fracture

No Association Between Opioid Intake and Patient Satisfaction After Ankle Fracture

By

To improve pain relief, surgeons should proactively address stress, distress, and ineffective coping strategies.

K-Postn May Be Predictor of Fx Risk in Postmenopausal Women Independent of BMD and FRAX

K-Postn May Be Predictor of Fx Risk in Postmenopausal Women Independent of BMD and FRAX

By

K-Postn may serve as a predictor of incident low-trauma fractures in postmenopausal women.

Sign Up for Free e-newsletters