Psoriasis

Dalazatide Effective Treatment for Skin Lesions in Plaque Psoriasis

Dalazatide Effective Treatment for Skin Lesions in Plaque Psoriasis

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Dalazatide treatment can improve skin lesions for patients with plaque psoriasis.

First Interchangeability Study Started for Adalimumab Biosimilar

First Interchangeability Study Started for Adalimumab Biosimilar

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The first US study to examine an interchangeability designation for an adalimumab biosimilar candidate is investigating interchangeability between BI 695501 and Humira 40mg/0.8mL.

Guidelines to Identify Risks of Pediatric Psoriasis Comorbidities

Guidelines to Identify Risks of Pediatric Psoriasis Comorbidities

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Risk factors for associated psoriasis comorbidities should be identified in patients with pediatric psoriasis.

Psoriasis Patients Have Higher Cardiometabolic Comorbidity Rates

Psoriasis Patients Have Higher Cardiometabolic Comorbidity Rates

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Psoriasis patients have high rates hyperlipidemia, hypertension, depression, type 2 diabetes mellitus, and obesity.

Chronic Inflammatory Disorders May Increase Cardiometabolic, Mortality Risks

Chronic Inflammatory Disorders May Increase Cardiometabolic, Mortality Risks

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The degree of risk for cardiometabolic events and all-cause mortality appeared to increase in participants who took nonsteroidal anti-inflammatory drugs or corticosteroid drugs.

Tofacitinib Found to Improve Nail Psoriasis

Tofacitinib Found to Improve Nail Psoriasis

There was improvement in nail psoriasis severity at 16 weeks compared with placebo that was maintained through 52 weeks.

No Negative Effect on Disease Activity Seen in Switching Patients to Biosimilar Infliximab From Originator Drug

No Negative Effect on Disease Activity Seen in Switching Patients to Biosimilar Infliximab From Originator Drug

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Researchers found similar disease duration the 3 months before and after the switch to CT-P13 in patients.

Uveitis Risk Higher Among Patients With Psoriasis

Uveitis Risk Higher Among Patients With Psoriasis

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Patients with severe psoriasis and those with mild psoriasis and concomitant psoriatic arthritis have an increased risk of uveitis.

First Line Biologic for Psoriasis Influenced By Certain Factors

First Line Biologic for Psoriasis Influenced By Certain Factors

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Psoriatic arthritis, patient weight, registration country and more influence first-line biologic treatment selection for patients with psoriasis.

Women Have Lower Psoriasis Area and Severity Index Scores Than Men

Women Have Lower Psoriasis Area and Severity Index Scores Than Men

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Women were found to have a lower median of scores in the Psoriasis Area and Severity Index than men.

Psoriatic Arthritis Development Predicted by Musculoskeletal Symptoms

Psoriatic Arthritis Development Predicted by Musculoskeletal Symptoms

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Prospective cohort study of patients with psoriasis who were assessed annually to examine for development of clinical psoriatic arthritis.

Secukinumab Efficacy for Psoriasis Examined After Treatment Pause

Secukinumab Efficacy for Psoriasis Examined After Treatment Pause

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Findings come from 2 trials; one compared secukinumab with placebo, whereas the other compared secukinumab with placebo and etanercept.

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

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Study reviewed information from 1.8 million individuals in England admitted to a hospital with an autoimmune disease.

Depression Significantly Increases Psoriatic Arthritis Risk Among Patients With Psoriasis

Depression Significantly Increases Psoriatic Arthritis Risk Among Patients With Psoriasis

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Study evaluated clinical data to determine a possible role of major depressive disorders in the progression of inflammatory disease.

Drug-Induced Lupus Observed With Adalimumab Treatment For Psoriasis

Drug-Induced Lupus Observed With Adalimumab Treatment For Psoriasis

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Investigators observe patient develop drug-induced lupus while taking biologic treatment for psoriasis.

FDA Approves Brodalumab Injection for Plaque Psoriasis Treatment

FDA Approves Brodalumab Injection for Plaque Psoriasis Treatment

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Siliq will carry a Black Box Warning and is available only through a restricted program.

Chronic Plaque Psoriasis Leads to Higher Fatigue Levels

Chronic Plaque Psoriasis Leads to Higher Fatigue Levels

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Study evaluated prevalence and severity of fatigue among patients with chronic plaque psoriasis and healthy controls.

Psoriasis Treatment Negatively Impacted By Interrupted Ixekizumab Therapy

Psoriasis Treatment Negatively Impacted By Interrupted Ixekizumab Therapy

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Most patients with psoriasis who were withdrawn from ixekizumab therapy experienced disease relapse.

Does Psoriatic Arthritis and Psoriasis Increase Risk of Fracture Development?

Does Psoriatic Arthritis and Psoriasis Increase Risk of Fracture Development?

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A population-based cohort study compared patients with psoriatic arthritis, psoriasis, and rheumatoid arthritis with matched comparators to determine fracture risk associated with the conditions.

Childhood Psoriasis Also Impacts Parents' Quality of Life

Childhood Psoriasis Also Impacts Parents' Quality of Life

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Emotional well-being negatively impacted among parents with affected children.

Systemic Arterial Inflammation Increased in Psoriasis

Systemic Arterial Inflammation Increased in Psoriasis

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Arterial inflammation and subcutaneous inflammation were significantly increased in patients with moderate-to-severe psoriasis

Comparative Long-term Effectiveness of Biologics for Psoriasis

Comparative Long-term Effectiveness of Biologics for Psoriasis

Ustekinumab had highest effectiveness during five years of tx; more dose escalation for etanercept.

Perceived Stigmatization Common for Those With Psoriasis

Perceived Stigmatization Common for Those With Psoriasis

Researchers found that lower education, higher disease visibility, severity, duration, and Type D personality were tied to stigmatization.

Physical Trauma Increases Risk for PsA Development in Psoriasis Patients

Physical Trauma Increases Risk for PsA Development in Psoriasis Patients

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Bone and joint trauma were independently associated with increased risk of psoriatic arthritis in patients with psoriasis

How Dermatologists Can Help Address Gaps in the Diagnosis of Psoriatic Arthritis

How Dermatologists Can Help Address Gaps in the Diagnosis of Psoriatic Arthritis

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Dermatologists are in a key position to screen for psoriatic arthritis (PsA), as the overlapping and variable symptoms of the disease require multidisciplinary care.

IL-12, IL-23 Inhibitor More Effective Than TNF Inhibitors in Psoriasis

IL-12, IL-23 Inhibitor More Effective Than TNF Inhibitors in Psoriasis

Ustekinumab was found to be more effective than three tumor necrosis factor-α inhibitors for the treatment of psoriasis.

Prognostic Utility of Antibodies to Adalimumab in RA, AS, and PsA

Prognostic Utility of Antibodies to Adalimumab in RA, AS, and PsA

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Study assessed the development of antibodies to adalimumab as a diagnostic indicator in rheumatoid arthritis, ankylosing spondylosis, and psoriatic arthritis.

Cytokine Converter Cell Implants Offer a Translational Approach to Treating Psoriasis and Other Chronic  Immune Disorders

Cytokine Converter Cell Implants Offer a Translational Approach to Treating Psoriasis and Other Chronic Immune Disorders

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Normal skin tissue morphology restored in psoriatic mice implanted with microencapsulated cytokine converter transgenic designer cells.

Quantifying Heritability and Genetic Sharing of Pediatric Autoimmune Disorders

Quantifying Heritability and Genetic Sharing of Pediatric Autoimmune Disorders

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Researchers quantified the heritability and genetic sharing for 9 pediatric autoimmune disorders.

FUTURE Trials Lead to Novel Treatment for Psoriatic Arthritis

FUTURE Trials Lead to Novel Treatment for Psoriatic Arthritis

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Results from the FUTURE trials demonstrate significant reduction in disease burden and severity of PsA with secukinumab.

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