Psoriatic Arthritis

Uveitis Risk Higher Among Patients With Psoriasis

Uveitis Risk Higher Among Patients With Psoriasis

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Patients with severe psoriasis and those with mild psoriasis and concomitant psoriatic arthritis have an increased risk of uveitis.

First Line Biologic for Psoriasis Influenced By Certain Factors

First Line Biologic for Psoriasis Influenced By Certain Factors

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Psoriatic arthritis, patient weight, registration country and more influence first-line biologic treatment selection for patients with psoriasis.

Biosimilar Confidence: Physician-Patient Communication Sets the Tone

Biosimilar Confidence: Physician-Patient Communication Sets the Tone

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Jonathan Krant, MD, FACP, confronts the issues surrounding biosimilar substitution for biologic treatments.

Measuring Disease Activity in Psoriatic Arthritis

Measuring Disease Activity in Psoriatic Arthritis

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There are many tools to evaluate disease activity in psoriatic arthritis, but there is no consensus on which one to use.

Women Have Lower Psoriasis Area and Severity Index Scores Than Men

Women Have Lower Psoriasis Area and Severity Index Scores Than Men

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Women were found to have a lower median of scores in the Psoriasis Area and Severity Index than men.

Psoriatic Arthritis Development Predicted by Musculoskeletal Symptoms

Psoriatic Arthritis Development Predicted by Musculoskeletal Symptoms

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Prospective cohort study of patients with psoriasis who were assessed annually to examine for development of clinical psoriatic arthritis.

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

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An observational cohort study of 4961 women with completed pregnancies and a recorded diagnosis of systemic inflammatory conditions.

Minimal Amount of TNF Inhibitor Transfers to Breast Milk, Study Finds

Minimal Amount of TNF Inhibitor Transfers to Breast Milk, Study Finds

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Study evaluated breast milk samples from 17 lactating mothers diagnosed with rheumatoid arthritis, Crohn's disease, psoriatic arthritis, and axial spondyloarthritis/ankylosing spondylitis.

Secukinumab Efficacy for Psoriasis Examined After Treatment Pause

Secukinumab Efficacy for Psoriasis Examined After Treatment Pause

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Findings come from 2 trials; one compared secukinumab with placebo, whereas the other compared secukinumab with placebo and etanercept.

Arthritis and Incident Myocardial Infarction Risk

Arthritis and Incident Myocardial Infarction Risk

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Research comes from meta-analysis of 25 population-based studies on 5 major forms of arthritis.

Depression Significantly Increases Psoriatic Arthritis Risk Among Patients With Psoriasis

Depression Significantly Increases Psoriatic Arthritis Risk Among Patients With Psoriasis

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Study evaluated clinical data to determine a possible role of major depressive disorders in the progression of inflammatory disease.

FDA Approves Brodalumab Injection for Plaque Psoriasis Treatment

FDA Approves Brodalumab Injection for Plaque Psoriasis Treatment

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Siliq will carry a Black Box Warning and is available only through a restricted program.

The Handoff: Your Week in Rheumatology News - 2/17/17

The Handoff: Your Week in Rheumatology News - 2/17/17

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Clinical management recommendations for juvenile dermatomyositis, updated guidelines for low back pain treatment, and more of this week's news.

Chronic Plaque Psoriasis Leads to Higher Fatigue Levels

Chronic Plaque Psoriasis Leads to Higher Fatigue Levels

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Study evaluated prevalence and severity of fatigue among patients with chronic plaque psoriasis and healthy controls.

Psoriasis Treatment Negatively Impacted By Interrupted Ixekizumab Therapy

Psoriasis Treatment Negatively Impacted By Interrupted Ixekizumab Therapy

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Most patients with psoriasis who were withdrawn from ixekizumab therapy experienced disease relapse.

Psoriatic Arthritis Strongly Linked With Developing Diabetes Mellitus

Psoriatic Arthritis Strongly Linked With Developing Diabetes Mellitus

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Researchers find that higher levels of disease activity predict the development of diabetes mellitus in patients with psoriatic arthritis.

Urinary Proteomic Biomarkers May Help Differentiate Inflammatory Arthritis

Urinary Proteomic Biomarkers May Help Differentiate Inflammatory Arthritis

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Researchers look for diagnostic alternative to blood samples for diagnosing specific inflammatory arthritis conditions.

Does Psoriatic Arthritis and Psoriasis Increase Risk of Fracture Development?

Does Psoriatic Arthritis and Psoriasis Increase Risk of Fracture Development?

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A population-based cohort study compared patients with psoriatic arthritis, psoriasis, and rheumatoid arthritis with matched comparators to determine fracture risk associated with the conditions.

Childhood Psoriasis Also Impacts Parents' Quality of Life

Childhood Psoriasis Also Impacts Parents' Quality of Life

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Emotional well-being negatively impacted among parents with affected children.

Increased Prevalence of Coronary Atherosclerosis in Psoriatic Arthritis

Increased Prevalence of Coronary Atherosclerosis in Psoriatic Arthritis

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The prevalence and severity of coronary atherosclerosis, measured by coronary CT angiography, were compared in patients with psoriatic arthritis and age/gender-matched controls.

Psoriasis Symptoms Reduced With Long-Term Weight Loss

Psoriasis Symptoms Reduced With Long-Term Weight Loss

Obese patients with psoriasis experience quality-of-life improvement after losing significant amounts of weight.

Psoriasis Among Skin Diseases With Largest Impact on Well-Being

Psoriasis Among Skin Diseases With Largest Impact on Well-Being

Highest risk for reduction in HRQoL for hidradenitis suppurativa, blistering conditions, psoriasis

Patients With Psoriatic Arthritis Experience Higher Fatigue

Patients With Psoriatic Arthritis Experience Higher Fatigue

Patients with psoriatic arthritis reportedly experience higher levels of fatigue versus those with psoriasis; fatigue scores linked to depression.

Case: PsA Development After Multiple Wasp Stings

Case: PsA Development After Multiple Wasp Stings

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Although rare, cases of arthritis associated with bee and wasp stings have been previously reported in the medical literature.

Janssen Seeks FDA Approval for Golimumab in PsA and AS

Janssen Seeks FDA Approval for Golimumab in PsA and AS

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The sBLAs included data from two Phase 3 studies that assessed the safety and efficacy of Simponi Aria 2mg/kg infusion every 8 weeks after two starter doses at Weeks 0 and 4 in adults with active psoriatic arthritis.

Increased Psoriasis Risk Linked to Prenatal Maternal Stress

Increased Psoriasis Risk Linked to Prenatal Maternal Stress

Relationship between psoriasis and maternal stress exists only for children born to a mother who lost an older child or their partner/spouse.

Efficacy of IL-23 Blockade Evaluated in Psoriatic Arthritis

Efficacy of IL-23 Blockade Evaluated in Psoriatic Arthritis

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Symptom improvements seen with subcutaneous guselkumab treatment tested in patients with psoriatic arthritis

Baseline PsA Characteristics Associated With bDMARD Response

Baseline PsA Characteristics Associated With bDMARD Response

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Data from the Corrona registry found that only 23.0% of patients were considered responders to their first biologic medication at the time of the second follow-up visit.

Efficacy of Tofacitinib in TNF-Inadequate Responders With PsA

Efficacy of Tofacitinib in TNF-Inadequate Responders With PsA

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In TNF inhibitor-inadequate responders with PsA, tofacitinib had superior ACR20 responses compared to placebo as early as 2 weeks after treatment initiation.

Depression as Determinant of PsA Minimal Disease Activity

Depression as Determinant of PsA Minimal Disease Activity

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Recognizing depression in PsA is important because psychological well-being may contribute to disease activity in PsA.

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