JAK/STAT Inhibitors: A New Treatment Target for Rheumatoid Arthritis

Janus kinase and signal transducers and activators of transcription inhibitors represent promising treatment targets in RA.

Cytomegalovirus Connection With Rheumatoid Arthritis Cardiovascular Disease Risk: An Expert Interview

Florian Kern, deputy director of research at Brighton and Sussex Medical School in the United Kingdom, discusses his recently published review wherein he and his ...

Rheumatoid Arthritis and Omega-3 Fatty Acids: Decades of Studies Yield No Clear Answer

Researchers have long been interested in whether omega-3 supplements can improve rheumatoid arthritis symptoms.

Juvenile Fibromyalgia Pain Treatment Enhanced By Psychosocial Impact Therapies

Novel psychosocial therapies such as cognitive behavioral therapy that have been effective in adults with fibromyalgia need additional neuromuscular fitness training to overcome catastrophizing and ...

Shared Decision-Making in Rheumatoid Arthritis

Patient care is more than providing treatment and measuring disease activity, says Jonathan Krant, MD, a rheumatologist from upstate New York. In this interview, the ...

Harnessing Neurostimulation to Target the Inflammatory Reflex in Rheumatoid Arthritis

Recent research may help guide future investigations into the use of "bioelectronic medicine" in diseases that are currently treated with pharmacotherapy.

Role of Physician Assistants and Nurse Practitioners in Rheumatology Practice

Nurse practitioners and physician assistants may help reduce shortages in the rheumatology workforce that are apparent in select communities, and further address treat-to-target inflammatory arthritis ...

Smartphone Apps Can Help Track Disease Activity in Rheumatoid Arthritis

Smartphone apps enable physicians to detect and explore similarities and discrepancies between objective and subjective data.

Noninferiority of Celecoxib to Ibuprofen & Naproxen for CV Events: Understanding Implications of the PRECISION Trial

Numerically fewer Antiplatelet Trialists Collaboration composite outcome events occurred with celecoxib treatment than with naproxen and ibuprofen. PRECISION lead investigator Dr Steven Nissen discusses clinical ...

EULAR/PReS Standards for Transitional Care of Juvenile-Onset Rheumatic Diseases

Panel advises that up to 50% of young patients with juvenile-onset rheumatic diseases fail to successfully transition to adult rheumatology services.

Latest News

Meta-Analysis: RA Treatment Outcomes Post-Methotrexate Failure

Meta-Analysis: RA Treatment Outcomes Post-Methotrexate Failure

The efficacy and tolerance of triple oral DMARD therapy vs. anti-TNF drugs plus methotrexate, was explored.

FDA Delays Approval of JAK Inhibitor Baricitinib

FDA Delays Approval of JAK Inhibitor Baricitinib

After 3-month extension to review, regulator says NDA for baricitinib cannot be approved in its current form.

Rheumatoid Arthritis Increases Mortality Risk in Staphylococcus aureus Infections

Rheumatoid Arthritis Increases Mortality Risk in Staphylococcus aureus Infections

Prospective cohort study examines clinical characteristics and outcomes of S aureus bacteremia in patients with rheumatoid arthritis.

Methotrexate-treated Rheumatoid Arthritis: No Liver Damage With Moderate Alcohol Use

Methotrexate-treated Rheumatoid Arthritis: No Liver Damage With Moderate Alcohol Use

Study analyzed medical records to determine whether alcohol consumption increases hepatotoxic risk in patients with rheumatoid arthritis being treated with methotrexate.

Second Biologic Effective in Rheumatoid Arthritis After Initial Treatment Failure

Second Biologic Effective in Rheumatoid Arthritis After Initial Treatment Failure

Investigators conduct a systematic review to evaluate the risks and benefits of biologics as monotherapy or in combination with methotrexate in patients with rheumatoid arthritis who have not responded to previous biologic treatment.

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

Study uses registry data from Sweden to evaluate heart failure risk before and after diagnosis of rheumatoid arthritis.

Tocilizumab Highly Effective in Refractory Juvenile Idiopathic Arthritis-associated Uveitis

Tocilizumab Highly Effective in Refractory Juvenile Idiopathic Arthritis-associated Uveitis

Tocilizumab therapy showed rapid improvement in ocular parameters for uveitis in juvenile idiopathic arthritis patients.

Glucocorticoids for Early Rheumatoid Arthritis Demonstrate Good Long-term Safety

Glucocorticoids for Early Rheumatoid Arthritis Demonstrate Good Long-term Safety

Researchers examined the long-term safety of glucocorticoid use in patients with early rheumatoid arthritis, defined as disease duration <6 months, from the multicenter observational Etude et Suivi des POlyarthrites Indifférenciées Récentes (ESPOIR) cohort.

EULAR Updates Rheumatoid Arthritis Treatment Guidelines for DMARDs

EULAR Updates Rheumatoid Arthritis Treatment Guidelines for DMARDs

EULAR has released new recommendations for rheumatoid arthritis management with disease-modifying antirheumatic drugs.

Sirukumab Rapidly Improves Rheumatoid Arthritis Symptoms in Difficult-to-Treat Patients

Sirukumab Rapidly Improves Rheumatoid Arthritis Symptoms in Difficult-to-Treat Patients

Study examined patients with active rheumatoid arthritis who failed to derive benefit from or were intolerant to TNF-inhibitor therapy.

Latest Slideshows

Alcohol Use: Surveying Effects on the Body's Major Systems

Alcohol Use: Surveying Effects on the Body's Major Systems

The effects of alcohol on the body's systems are examined here, with both damaging and potentially protective effects being explored. ...

Ten Unusually Specific ICD-10 Codes

Ten Unusually Specific ICD-10 Codes

With nearly 70,000 ICD-10 diagnosis codes available to clinicians, things are bound to get interesting.

Role of Vitamin D in Rheumatoid Arthritis Pathogenesis

Role of Vitamin D in Rheumatoid Arthritis Pathogenesis

Increasing evidence indicates serum vitamin D levels and polymorphisms in enzymes involved in vitamin D metabolism can affect the risk ...

Mitigating Risk of Cardiovascular Disease in Rheumatoid Arthritis

Mitigating Risk of Cardiovascular Disease in Rheumatoid Arthritis

Patients with rheumatoid arthritis have an increased risk of developing cardiovascular disease (CVD) and CVD-related mortality compared with the general ...

Examining Patient-Reported Outcomes in Rheumatoid Arthritis

Examining Patient-Reported Outcomes in Rheumatoid Arthritis

Validation of a patient-report outcome instrument as an effective independent tool for measuring disease activity and treatment response may one ...

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