Rheumatoid Arthritis

Assessing the Diagnostic Accuracy of MRI in Early Rheumatoid Arthritis

Assessing the Diagnostic Accuracy of MRI in Early Rheumatoid Arthritis

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Researchers say that MRI of the hand and foot can be used in the early diagnostic process of RA in patients with UA.

Peficitinib Shows Dose-Dependent ACR20 Response Rates in RA

Peficitinib Shows Dose-Dependent ACR20 Response Rates in RA

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Peficitinib combined with certain csDMARDs results in a dose-dependent ACR20 response rate in patients with RA.

Physician Assistants May Help Fill Rheumatology Workforce Shortage

Physician Assistants May Help Fill Rheumatology Workforce Shortage

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The gap between supply and demand for rheumatologists is expected to widen substantially by 2030.

Combining High-Frequency Ultrasound With Anti-CCP Testing for Early RA Diagnosis

Combining High-Frequency Ultrasound With Anti-CCP Testing for Early RA Diagnosis

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High-frequency color Doppler ultrasonography together with anti-cyclic citrullinated peptide antibody testing may allow for earlier diagnosis of rheumatoid arthritis.

Antipsychotic Nonadherence Greater Than for Somatic Illness Due to Social Stigma

Antipsychotic Nonadherence Greater Than for Somatic Illness Due to Social Stigma

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Schizophrenia was perceived as more distressful and with higher perceived social stigma than the other disorders analyzed.

Ultrasound Remission, Health Status Not Correlated in RA in Clinical Remission

Ultrasound Remission, Health Status Not Correlated in RA in Clinical Remission

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No clear association between health status and ultrasound remission was evident in patients with rheumatoid arthritis in clinical remission.

Rheumatoid Arthritis and Asthma: Is There a Link?

Rheumatoid Arthritis and Asthma: Is There a Link?

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Rheumatoid arthritis and asthma have a strong association that could enable earlier disease recognition and improved treatments.

Low Disease Activity After Tofacitinib Discontinuation in Rheumatoid Arthritis

Low Disease Activity After Tofacitinib Discontinuation in Rheumatoid Arthritis

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Researchers found that one-third of patients remain in remission after discontinuing tofacitinib and that low baseline RF titers predict low disease activity after tofacitinib discontinuation.

Good Long-Term Outcomes Seen With Early Rheumatoid Arthritis Treatment

Good Long-Term Outcomes Seen With Early Rheumatoid Arthritis Treatment

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Early rheumatoid arthritis treatment leads to improvement in long-term outcomes.

Early Rheumatoid Arthritis Treatment Important for Long-Term Outcomes

Early Rheumatoid Arthritis Treatment Important for Long-Term Outcomes

One study shows a drop in mortality attributable to rheumatoid arthritis from 1987 to 2011.

No Association Between Arthritis and Cognitive Impairment in Older Adults

No Association Between Arthritis and Cognitive Impairment in Older Adults

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Study examines data from the Health and Retirement Study (HRS) to identify any cross-sectional association between arthritis and cognitive impairment in older adults.

Preferred Treatment to Reduce GI Bleeding Risk With NSAIDS in OA, RA

Preferred Treatment to Reduce GI Bleeding Risk With NSAIDS in OA, RA

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Celecoxib plus a proton pump inhibitor reduces risk for recurrent upper gastrointestinal bleeding in patients with arthritis using NSAIDs who are at risk for cardiovascular, gastrointestinal events.

ICER Concludes Targeted Immunomodulators Are Overpriced: Advocacy Organizations Express Concern

ICER Concludes Targeted Immunomodulators Are Overpriced: Advocacy Organizations Express Concern

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ICER found TIMs to be efficacious overall but did not find them to be cost-effective.

Bi-Directional Links Between Rheumatoid Arthritis and Periodontal Disease

Bi-Directional Links Between Rheumatoid Arthritis and Periodontal Disease

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Periodontal disease may be the main precipitating factor in the development of rheumatoid arthritis by fostering the environment for multiple destructive mechanisms that attack synovial joints.

Infliximab Biosimilar Now FDA Approved for RA, PsA, AS

Infliximab Biosimilar Now FDA Approved for RA, PsA, AS

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Renflexis is a TNF blocker indicated for Crohn's disease, pediatric Crohn's disease, ulcerative colitis, rheumatoid arthritis in combination with methotrexate, ankylosing spondylitis, psoriatric arthritis, and plaque psoriasis.

Rheumatoid Arthritis and Metabolic Syndrome: High Prevalence and Risk

Rheumatoid Arthritis and Metabolic Syndrome: High Prevalence and Risk

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Researchers from Iran conduct a meta-analysis to determine the prevalence and risk for metabolic syndrome among patients with rheumatoid arthritis.

Meta-Analysis: RA Treatment Outcomes Post-Methotrexate Failure

Meta-Analysis: RA Treatment Outcomes Post-Methotrexate Failure

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The efficacy and tolerance of triple oral DMARD therapy vs. anti-TNF drugs plus methotrexate, was explored.

FDA Delays Approval of JAK Inhibitor Baricitinib

FDA Delays Approval of JAK Inhibitor Baricitinib

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After 3-month extension to review, regulator says NDA for baricitinib cannot be approved in its current form.

Rheumatoid Arthritis Increases Mortality Risk in <i>Staphylococcus aureus</i> Infections

Rheumatoid Arthritis Increases Mortality Risk in Staphylococcus aureus Infections

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Prospective cohort study examines clinical characteristics and outcomes of S aureus bacteremia in patients with rheumatoid arthritis.

Biosimilar Confidence: Physician-Patient Communication Sets the Tone

Biosimilar Confidence: Physician-Patient Communication Sets the Tone

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Jonathan Krant, MD, FACP, confronts the issues surrounding biosimilar substitution for biologic treatments.

The Handoff: Your Week in Rheumatology News - 4/14/17

The Handoff: Your Week in Rheumatology News - 4/14/17

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This week, a phase III trial for investigational drug voclosporin for lupus nephritis treatment was approved, prolonged insomnia may lead to less robust bone formation — causing osteoporosis and bone fractures — and researchers found that women who drink a moderate amount of alcohol daily have a reduced risk of developing systemic lupus erythmatosus.

Methotrexate-treated Rheumatoid Arthritis: No Liver Damage With Moderate Alcohol Use

Methotrexate-treated Rheumatoid Arthritis: No Liver Damage With Moderate Alcohol Use

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Study analyzed medical records to determine whether alcohol consumption increases hepatotoxic risk in patients with rheumatoid arthritis being treated with methotrexate.

Second Biologic Effective in Rheumatoid Arthritis After Initial Treatment Failure

Second Biologic Effective in Rheumatoid Arthritis After Initial Treatment Failure

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Investigators conduct a systematic review to evaluate the risks and benefits of biologics as monotherapy or in combination with methotrexate in patients with rheumatoid arthritis who have not responded to previous biologic treatment.

The Handoff: Your Week in Rheumatology News - 4/7/17

The Handoff: Your Week in Rheumatology News - 4/7/17

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WCO 2017, FDA grants Rituxan Breakthrough Therapy status, and a close-up of pediatric Sjögren's syndrome highlight this week's The Handoff.

FDA Grants Breakthrough Therapy Designation to Rituxan

FDA Grants Breakthrough Therapy Designation to Rituxan

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FDA gives breakthrough therapy designation to rituxan for treatment of pemphigus vulgaris and is indicated for treating rheumatoid arthritis

Rheumatoid Arthritis, Systemic Sclerosis Patients Should Have Hand Function Evaluated

Rheumatoid Arthritis, Systemic Sclerosis Patients Should Have Hand Function Evaluated

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Study evaluated hand function and potential influence of functional loss on patients' overall physical functions, health-related quality of life, and psychological status in patients with rheumatoid arthritis and systemic sclerosis.

JAK/STAT Inhibitors:  A New Treatment Target for Rheumatoid Arthritis

JAK/STAT Inhibitors: A New Treatment Target for Rheumatoid Arthritis

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Janus kinase and signal transducers and activators of transcription inhibitors represent promising treatment targets in RA.

Knee Osteoarthritis in Early Rheumatoid Arthritis May Affect Disease Activity Evaluation

Knee Osteoarthritis in Early Rheumatoid Arthritis May Affect Disease Activity Evaluation

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A small study from Romania evaluated whether the presence of osteoarthritis had an effect on the parameters used to evaluate disease activity in patients with early rheumatoid arthritis.

Ultrasound Finds Distinct Ankle Pathologies In Rheumatic Diseases

Ultrasound Finds Distinct Ankle Pathologies In Rheumatic Diseases

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Ultrasonography detects different ankle pathologies in various inflammatory rheumatic diseases.

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

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Study uses registry data from Sweden to evaluate heart failure risk before and after diagnosis of rheumatoid arthritis.

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