Rheumatoid Arthritis

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

DPP-4 Inhibitors and Incidence of Rheumatoid Arthritis in Type 2 Diabetes

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Investigators sought to determine whether the use of dipeptidyl peptidase-4 inhibitors is associated with the incidence of rheumatoid arthritis.

Examining Gaps in Mental Health Care Among Youth With Juvenile Rheumatic Disease

Examining Gaps in Mental Health Care Among Youth With Juvenile Rheumatic Disease

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There is an unmet need for mental health interventions that address illness-related issues affecting youth with rheumatologic conditions.

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

Efficacy of ABT-122 Maintained in Psoriatic Arthritis, Rheumatoid Arthritis at 36 Weeks

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ABT-122 demonstrated acceptable tolerability and maintenance of efficacy at 36 weeks in patients with RA or PsA receiving background methotrexate.

Flu Vaccine Cuts Mortality in Patients With Rheumatoid Arthritis

Flu Vaccine Cuts Mortality in Patients With Rheumatoid Arthritis

Patients with RA, particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality.

Novel Visual Scoring Method Detects Cortical Interruptions in RA With HR-pQCT

Novel Visual Scoring Method Detects Cortical Interruptions in RA With HR-pQCT

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The scoring method allows detection of small cortical interruptions on HR-pQCT imaging of finger joints.

Continuing, Switching TNFi After Serious Infection Reduces Likelihood of Recurrent Infection

Continuing, Switching TNFi After Serious Infection Reduces Likelihood of Recurrent Infection

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Patients who continued or switched their TNF inhibitor after a serious infection had a lower risk for recurrent infection compared with those who stopped the drug.

Poor Prognostic Factors in Rheumatoid Arthritis May Not Affect Treatment Choices, Outcomes

Poor Prognostic Factors in Rheumatoid Arthritis May Not Affect Treatment Choices, Outcomes

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Researchers sought to characterize patients with rheumatoid arthritis by the number of poor prognostic factors and evaluate treatment acceleration, clinical outcomes, and work status.

Worldwide Access to bDMARDs Influenced by Socioeconomic Status, Prescription Rules

Worldwide Access to bDMARDs Influenced by Socioeconomic Status, Prescription Rules

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Disease activity in patients with rheumatoid arthritis and access to bDMARD care varies across countries worldwide.

Depression Management Needed in Routine Clinical Practice for Working-Age Adults With RA

Depression Management Needed in Routine Clinical Practice for Working-Age Adults With RA

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Depression screening and management should be incorporated into routine clinical care of patients with RA to reduce pain and functional limitations, improve quality of life, and lower healthcare costs.

Predictors of Influenza Vaccine Acceptance in Patients With Inflammatory Rheumatic Diseases

Predictors of Influenza Vaccine Acceptance in Patients With Inflammatory Rheumatic Diseases

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A direct recommendation from physicians had the greatest effect on patients' positive vaccination status.

PROMIS Effective for Physical, Mental Health Assessment in DMARD-Treated Rheumatoid Arthritis

PROMIS Effective for Physical, Mental Health Assessment in DMARD-Treated Rheumatoid Arthritis

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PROMIS measures can detect changes in symptoms of global health, pain, sleep, fatigue, and emotional health in patients with rheumatoid arthritis who are initiating DMARD therapy.

Patient-Reported Disease Activity Correlates With Adverse Pregnancy Outcomes in RA

Patient-Reported Disease Activity Correlates With Adverse Pregnancy Outcomes in RA

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A clear difference exists in the utility of patient-reported measures of disease activity in women with SLE and those with RA.

Similar Quality of Life Reported in Rheumatoid Arthritis, Psoriatic Arthritis

Similar Quality of Life Reported in Rheumatoid Arthritis, Psoriatic Arthritis

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Health-related quality of life was similar in patients with rheumatoid arthritis and psoriatic arthritis.

Antibiotic-Methotrexate Combination Leads to Serious Side Effects in a Patient With RA

Antibiotic-Methotrexate Combination Leads to Serious Side Effects in a Patient With RA

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The case involved a 68-year-old female patient with rheumatoid arthritis on methotrexate 10 mg weekly who presented to the emergency department with complaints of lethargy and weakness after being prescribed a 2-week course of trimethoprim-sulfamethoxazole for a bacterial skin infection.

Fatigue Affects Work Disability in Rheumatoid Arthritis, Ankylosing Spondylitis

Fatigue Affects Work Disability in Rheumatoid Arthritis, Ankylosing Spondylitis

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Fatigue had a significant and independent effect on work disability measures in rheumatoid arthritis and ankylosing spondylitis.

Multisystem Intervention Reduces Missed Opportunities for Influenza Vaccination in RA

Multisystem Intervention Reduces Missed Opportunities for Influenza Vaccination in RA

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Many patients with rheumatoid arthritis currently experience missed opportunities to be vaccinated against influenza.

RA Associated With Greater Reduction in Short-Term Disease Burden vs Osteoarthritis

RA Associated With Greater Reduction in Short-Term Disease Burden vs Osteoarthritis

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Investigators analyzed MDHAQ/RAPID3 scores in patients with osteoarthritis or rheumatoid arthritis to assess disease burden associated with each rheumatic disease.

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

Tofacitinib May Effectively Alleviate Pain in RA, Psoriatic Arthritis, and Ankylosing Spondylitis

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Tofacitinib may provide a fast and prolonged analgesic effect in patients with rheumatoid arthritis or psoriatic arthritis who are unresponsive to csDMARD or to TNFi, as well as in individuals with ankylosing spondylitis.

RA: Psychological State Predicts Disease Flare Following TNF Tapering

RA: Psychological State Predicts Disease Flare Following TNF Tapering

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Based on these results, clinicians should consider assessing functional and mental health states before biologic tapering.

RA: MRI Values May Not Benefit Clinical, Radiographic Outcomes in Treat-to-Target Strategy

RA: MRI Values May Not Benefit Clinical, Radiographic Outcomes in Treat-to-Target Strategy

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Researchers sought to determine whether a treat-to-target strategy based on MRI assessments targeting absence bone marrow edema would lead to improved clinical and radiographic outcomes.

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

Initial High Disease Activity in Rheumatoid Arthritis Linked to Depression

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Investigators sought to determine whether initial high disease activity or changes in disease activity contribute to the development of persistent depression among patients with early rheumatoid arthritis.

Upadacitinib Monotherapy Yields Positive Results in Phase 3 Rheumatoid Arthritis Study

Upadacitinib Monotherapy Yields Positive Results in Phase 3 Rheumatoid Arthritis Study

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Results of the phase 3 SELECT-EARLY study show positive results for upadacitinib in adult patients with moderate to severe rheumatoid arthritis.

RA Treatment Unlikely to Improve Mental Health Outcomes

RA Treatment Unlikely to Improve Mental Health Outcomes

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Mental health outcomes in patients with RA are unlikely to resolve with effective RA pharmacological disease management alone.

FDA Approves Baricitinib for Adults With Active Rheumatoid Arthritis

FDA Approves Baricitinib for Adults With Active Rheumatoid Arthritis

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The FDA has approved baricitinib for the treatment of adults with active rheumatoid arthritis who have had an inadequate response to ≥1 tumor necrosis factor antagonist.

Predictors of Post-Chikungunya Chronic Polyarthralgia

Predictors of Post-Chikungunya Chronic Polyarthralgia

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Researchers reported on the first outbreak of an Asian lineage of chikungunya virus in Aruba.

RA Treatment During Pregnancy: Is Infection Risk Greater in Offspring?

RA Treatment During Pregnancy: Is Infection Risk Greater in Offspring?

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Children exposed to TNFi's during the gestational period were found not to have a significantly higher risk of developing serious infections.

HBV Status Linked to Disease Activity and Progression in Rheumatoid Arthritis

HBV Status Linked to Disease Activity and Progression in Rheumatoid Arthritis

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Patients with rheumatoid arthritis with chronic hepatitis B virus infection demonstrated greater radiographic progression and poorer clinical response at 1 year.

Risks Associated With Co-Administration of Aspirin and Other NSAIDs

Risks Associated With Co-Administration of Aspirin and Other NSAIDs

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In patients with rheumatoid arthritis or osteoarthritis who are at higher risk for cardiovascular events, celecoxib may be safer compared with naproxen or ibuprofen when these drugs are taken alone or in combination with aspirin.

Corticosteroid-Related Adverse Events Examined Based on Dose, Duration

Corticosteroid-Related Adverse Events Examined Based on Dose, Duration

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Using a privately-insured administrative database, researchers examined a total of 78,704 patients with autoimmune or inflammatory disease diagnoses between 2006 and 2015.

RA: Low Probability of Achieving LDA With Lack of Early Response to Tofacitinib

RA: Low Probability of Achieving LDA With Lack of Early Response to Tofacitinib

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This study sought to examine the link between early disease activity changes and attainment of LDA and remission targets in tofacitinib-treated patients with RA.

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