Rheumatoid Arthritis

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

Rheumatoid Arthritis Increases Nonischemic Heart Failure Risk

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Study uses registry data from Sweden to evaluate heart failure risk before and after diagnosis of rheumatoid arthritis.

The Handoff: Your Week in Rheumatology News - 3/24/17

The Handoff: Your Week in Rheumatology News - 3/24/17

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New guidelines for rheumatoid arthritis treatment with DMARDs and money being steered into lupus research highlight this week's The Handoff.

Tocilizumab Highly Effective in Refractory Juvenile Idiopathic Arthritis-associated Uveitis

Tocilizumab Highly Effective in Refractory Juvenile Idiopathic Arthritis-associated Uveitis

Tocilizumab therapy showed rapid improvement in ocular parameters for uveitis in juvenile idiopathic arthritis patients.

Glucocorticoids for Early Rheumatoid Arthritis Demonstrate Good Long-term Safety

Glucocorticoids for Early Rheumatoid Arthritis Demonstrate Good Long-term Safety

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Researchers examined the long-term safety of glucocorticoid use in patients with early rheumatoid arthritis, defined as disease duration <6 months, from the multicenter observational Etude et Suivi des POlyarthrites Indifférenciées Récentes (ESPOIR) cohort.

EULAR Updates Rheumatoid Arthritis Treatment Guidelines for DMARDs

EULAR Updates Rheumatoid Arthritis Treatment Guidelines for DMARDs

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EULAR has released new recommendations for rheumatoid arthritis management with disease-modifying antirheumatic drugs.

Sirukumab Rapidly Improves Rheumatoid Arthritis Symptoms in Difficult-to-Treat Patients

Sirukumab Rapidly Improves Rheumatoid Arthritis Symptoms in Difficult-to-Treat Patients

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Study examined patients with active rheumatoid arthritis who failed to derive benefit from or were intolerant to TNF-inhibitor therapy.

Rheumatoid Arthritis Increases Heart Failure Risk

Rheumatoid Arthritis Increases Heart Failure Risk

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Analysis finds rapid increase in the risk of non-ischemic heart failure after onset of rheumatoid arthritis.

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

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An observational cohort study of 4961 women with completed pregnancies and a recorded diagnosis of systemic inflammatory conditions.

Arthritis Disability Up 20% Since 2002, Says CDC Report

Arthritis Disability Up 20% Since 2002, Says CDC Report

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One in four adults in the U.S. have been diagnosed with arthritis.

Secukinumab Improves Symptoms in TNF Inhibitor-Refractory Rheumatoid Arthritis

Secukinumab Improves Symptoms in TNF Inhibitor-Refractory Rheumatoid Arthritis

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A phase 3, double-blind, randomized placebo-controlled study was conducted in 551 patients with active rheumatoid arthritis who received secukinumab, abatacept, or placebo.

Minimal Amount of TNF Inhibitor Transfers to Breast Milk, Study Finds

Minimal Amount of TNF Inhibitor Transfers to Breast Milk, Study Finds

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Study evaluated breast milk samples from 17 lactating mothers diagnosed with rheumatoid arthritis, Crohn's disease, psoriatic arthritis, and axial spondyloarthritis/ankylosing spondylitis.

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

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Study reviewed information from 1.8 million individuals in England admitted to a hospital with an autoimmune disease.

The Handoff: Your Week in Rheumatology News - 3/3/17

The Handoff: Your Week in Rheumatology News - 3/3/17

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Connecticut considers rheumatoid arthritis and fibromyalgia for medical marijuana treatment, while Lyme disease-carrying deer ticks continue to invade Michigan. All this and more in this week's edition.

Arthritis and Incident Myocardial Infarction Risk

Arthritis and Incident Myocardial Infarction Risk

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Research comes from meta-analysis of 25 population-based studies on 5 major forms of arthritis.

Tocilizumab Cardiovascular Risk in Rheumatoid Arthritis

Tocilizumab Cardiovascular Risk in Rheumatoid Arthritis

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Cohort study of patients with rheumatoid arthritis who newly initiated tocilizumab or tumor necrosis factor inhibitor therapy using multi-database claims data.

Baricitinib Superior to Adalimumab for Rheumatoid Arthritis Treatment

Baricitinib Superior to Adalimumab for Rheumatoid Arthritis Treatment

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Phase 3 trial in patients taking baricitinib, adalimumab, or placebo in addition to methotrexate background therapy.

Cytomegalovirus Connection With Rheumatoid Arthritis Cardiovascular Disease Risk: An Expert Interview

Cytomegalovirus Connection With Rheumatoid Arthritis Cardiovascular Disease Risk: An Expert Interview

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Florian Kern, deputy director of research at Brighton and Sussex Medical School in the United Kingdom, discusses his recently published review wherein he and his colleagues make the case that cytomegalovirus is a major driver of cardiovascular disease in patients with rheumatoid arthritis.

Rheumatoid Arthritis and Omega-3 Fatty Acids: Decades of Studies Yield No Clear Answer

Rheumatoid Arthritis and Omega-3 Fatty Acids: Decades of Studies Yield No Clear Answer

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Researchers have long been interested in whether omega-3 supplements can improve rheumatoid arthritis symptoms.

Efficacy of JAK Monotherapy vs Combination Therapy in RA

Efficacy of JAK Monotherapy vs Combination Therapy in RA

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Twelve-month trial compared tofacitinib with adalimumab as monotherapy or in combination with methotrexate.

Juvenile Arthritis with Sleep Apnea Impairs Neurobehavioral Performance

Juvenile Arthritis with Sleep Apnea Impairs Neurobehavioral Performance

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Study examines children with juvenile idiopathic arthritis who underwent overnight polysomnography and neurobehavioral assessments.

Infliximab Discontinuation and Postoperative Infection Risk

Infliximab Discontinuation and Postoperative Infection Risk

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Study examined patients who received infliximab for rheumatologic conditions and the incidence of postoperative infections.

Ultrasound Identifies Tenosynovitis in RA Patients With Low DAS28 Scores

Ultrasound Identifies Tenosynovitis in RA Patients With Low DAS28 Scores

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Standardized ultrasound assessment of rheumatoid arthritis disease activity may aid healthcare practitioners in comprehensive management.

Short-Course Tocilizumab for Rheumatoid Arthritis May Increase HBV Reactivation

Short-Course Tocilizumab for Rheumatoid Arthritis May Increase HBV Reactivation

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Prospective observational study yields patients with hepatitis B reactivation, but all were asymptomatic.

Review of Biologic Tapering Strategies in Rheumatoid Arthritis

Review of Biologic Tapering Strategies in Rheumatoid Arthritis

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The researchers identified six key pieces of information that may help clinicians in selecting the optimal patient for successful de-escalation of biologic DMARD.

Juvenile Fibromyalgia Pain Treatment Enhanced By Psychosocial Impact Therapies

Juvenile Fibromyalgia Pain Treatment Enhanced By Psychosocial Impact Therapies

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Novel psychosocial therapies such as cognitive behavioral therapy that have been effective in adults with fibromyalgia need additional neuromuscular fitness training to overcome catastrophizing and fear of exercise in adolescents.

Etanercept for Rheumatoid Arthritis Has Lower Infection Risk

Etanercept for Rheumatoid Arthritis Has Lower Infection Risk

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The TNF inhibitor shows lower risk for infections and tuberculosis, according to a recent study.

Predicting Lowest Effective Dose For Biologics in Rheumatoid Arthritis Treatment

Predicting Lowest Effective Dose For Biologics in Rheumatoid Arthritis Treatment

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Study finds weak evidence for using biomarkers as a guide to tapering or discontinuing biologic therapy in patients with rheumatoid arthritis.

Rheumatoid Arthritis Increases Risk of Cardiovascular Disease Events After Fragility Fracture

Rheumatoid Arthritis Increases Risk of Cardiovascular Disease Events After Fragility Fracture

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Study investigators suggest clinicians consider more aggressive preventive therapy for cardiovascular disease in patients with rheumatoid arthritis who have experienced a fragility fracture.

Pneumonia Vaccine Effectiveness Questioned in Rheumatoid Arthritis Patients

Pneumonia Vaccine Effectiveness Questioned in Rheumatoid Arthritis Patients

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Study authors say results indicate vaccine may not be effective for pneumonia in patients with rheumatoid arthritis at high risk for infections.

Shared Decision-Making in Rheumatoid Arthritis

Shared Decision-Making in Rheumatoid Arthritis

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Patient care is more than providing treatment and measuring disease activity, says Jonathan Krant, MD, a rheumatologist from upstate New York. In this interview, the chief of medicine for the Adirondack Health System explains the disconnect between what physicians would like to learn from their patients and what their time constraints allow.

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