Rheumatoid Arthritis

When Other Disease-Modifying Antirheumatic Drugs Don't Work, Try Sirukumab

When Other Disease-Modifying Antirheumatic Drugs Don't Work, Try Sirukumab

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For patients with active rheumatoid arthritis who are not responding to DMARDs, sirukumab may represent a safe and effective treatment.

Reactivation Rate of Hepatitis B in Inflammatory Arthritis Tx With DMARDs

Reactivation Rate of Hepatitis B in Inflammatory Arthritis Tx With DMARDs

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HBV reactivation rates were lower among all chronic HBV infection patients on antiviral prophylaxis, regardless of whether they were receiving TNF inhibitors.

COBRA vs COBRA-Light for Rheumatoid Arthritis: Assessing Efficacy, Safety

COBRA vs COBRA-Light for Rheumatoid Arthritis: Assessing Efficacy, Safety

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Patients recently diagnosed with rheumatoid arthritis showed similar efficacy and safety outcomes during a 4-year follow-up period after receiving treatment with COBRA-light or COBRA therapy.

Live Zoster Vaccination Safe in RA Prior to Tofacitinib Initiation

Live Zoster Vaccination Safe in RA Prior to Tofacitinib Initiation

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Herpes zoster vaccine shown to be safe in patients with rheumatoid arthritis.

SB4 vs Etanercept in Rheumatoid Arthritis: Long-term Efficacy and Safety

SB4 vs Etanercept in Rheumatoid Arthritis: Long-term Efficacy and Safety

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Switching from ETN to SB4 was not associated with a loss of efficacy, a rise in TEAEs, or an increase in immunogenicity.

No Association Between Opioid Intake and Patient Satisfaction After Ankle Fracture

No Association Between Opioid Intake and Patient Satisfaction After Ankle Fracture

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To improve pain relief, surgeons should proactively address stress, distress, and ineffective coping strategies.

Minimal Transfer of Certolizumab Pegol to Mature Breast Milk

Minimal Transfer of Certolizumab Pegol to Mature Breast Milk

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The first lactation study of its kind evaluated whether a biologic drug is transferred into mature breast milk

RA: Serious Infection Event Rate Comparable With Tofacitinib vs Baricitinib

RA: Serious Infection Event Rate Comparable With Tofacitinib vs Baricitinib

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The risk for serious infection events in rheumatoid arthritis with tofacitinib is compatible to risk rates of biologic disease-modifying antirheumatic drugs and baricitinib.

Tocilizumab Associated With Improved Anemia Markers in Patients With Rheumatoid Arthritis

Tocilizumab Associated With Improved Anemia Markers in Patients With Rheumatoid Arthritis

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Other biologic DMARDs were not associated with any significant clinically meaningful increase in Hb and Hct levels.

Differences in RA Treatment Goals Between Patients and Healthcare Providers

Differences in RA Treatment Goals Between Patients and Healthcare Providers

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A physician- and patient-based survey revealed differences in treatment goals, patient concerns, and more.

Assessing Vaccine Safety for Young People With Rheumatic Disorders

Assessing Vaccine Safety for Young People With Rheumatic Disorders

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The effect of rheumatic disease on vaccine safety in children was examined.

FDA Approval of Biosimilar Cyltezo for Multiple Indications

FDA Approval of Biosimilar Cyltezo for Multiple Indications

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Cyltezo subcutaneous injection has been approved by the FDA.

Case Study: Rheumatoid Arthritis Cardiac Manifestations

Case Study: Rheumatoid Arthritis Cardiac Manifestations

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A 69 year old man presents joint pain (wrists, elbows, hands, and knees) and swelling with no evidence of erosions.

ACS Risk Increased in New-Onset RA Despite Improved Disease Control

ACS Risk Increased in New-Onset RA Despite Improved Disease Control

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Individuals with new-onset rheumatoid arthritis are at increased risk of acute coronary syndrome.

Tocilizumab and Prednisone Taper Sustain Giant-Cell Arteritis Remission

Tocilizumab and Prednisone Taper Sustain Giant-Cell Arteritis Remission

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The giant cell arteritis treatment tocilizumab has been approved by the FDA.

Over 300,000 Deaths From Rheumatic Heart Disease in 2015 Worldwide

Over 300,000 Deaths From Rheumatic Heart Disease in 2015 Worldwide

There was an estimated 319,400 deaths in 2015, due to rheumatic heart disease.

Increased Risk for Diabetes in Patients With Poorly Controlled Rheumatoid Arthritis

Increased Risk for Diabetes in Patients With Poorly Controlled Rheumatoid Arthritis

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Patients with both RA and T2D - each shown to be independent risk factors for CVD - are at even higher risk for developing CVD and related mortality.

Oral Contraceptives Linked to Lower Risk of Rheumatoid Arthritis

Oral Contraceptives Linked to Lower Risk of Rheumatoid Arthritis

Oral contraception use has been shown to be linked to a lower risk of rheumatoid arthritis.

Rheumatoid Factor Ups Risk of 10-Year Cardiovascular Morbidity

Rheumatoid Factor Ups Risk of 10-Year Cardiovascular Morbidity

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Rheumatoid factor positivity was associated with occurrence of CVD, independently from anti-CCP positivity.

Noxious Fumes Exposure at Work May Up Risk of Rheumatoid Arthritis

Noxious Fumes Exposure at Work May Up Risk of Rheumatoid Arthritis

Certain occupations such as bricklayers, concrete workers, material handling operators, and electrical workers have a higher risk of rheumatoid arthritis.

Rheumatoid Factor Raises Risk of 10-Year Cardiovascular Morbidity

Rheumatoid Factor Raises Risk of 10-Year Cardiovascular Morbidity

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Rheumatoid factor positivity was associated with occurrence of CVD, independently from anti-CCP positivity.

Rituximab Biosimilar Shows Bioequivalency to Reference Biologics

Rituximab Biosimilar Shows Bioequivalency to Reference Biologics

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Biosimilar GP2013 demonstrated bioequivalency to its reference biologic, rituximab, in patients with active rheumatoid arthritis.

Rheumatic Manifestations of HCV: New Treatment Options

Rheumatic Manifestations of HCV: New Treatment Options

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Patients with HCV are at risk for several extrahepatic sequelae. Find out what they are, and the new treatment options for managing HCV in RA.

No Association Between Postop Opioid Intake and Patient Satisfaction After Ankle Fracture

No Association Between Postop Opioid Intake and Patient Satisfaction After Ankle Fracture

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To improve pain relief, surgeons should proactively address stress, distress, and ineffective coping strategies.

Herpes Zoster Risk Increased With TNFi in Patients With RA

Herpes Zoster Risk Increased With TNFi in Patients With RA

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Patients with rheumatoid arthritis using tumor necrosis factor inhibitors and corticosteroids have increased risk of herpes zoster.

Adalimumab Biosimilar ABP 501 Safe, Effective for Psoriasis

Adalimumab Biosimilar ABP 501 Safe, Effective for Psoriasis

ABP 501 is safe to use for treating moderate to severe plaque psoriasis.

OMERACT Assessment Effectively Identifies Rheumatoid Arthritis Flares

OMERACT Assessment Effectively Identifies Rheumatoid Arthritis Flares

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Preliminary findings suggest that the OMERACT flare assessment tool is effective for identifying RA flares, with high agreement between providers and patients on flare status.

Effects of Morphine in Rheumatoid Arthritis Similar to Placebo

Effects of Morphine in Rheumatoid Arthritis Similar to Placebo

Morphine has anti-hyperalgesic effects comparable to placebo for patients with CFS/FM or RA.

Response to Methotrexate in RA May Be Predicted by Gene Expression

Response to Methotrexate in RA May Be Predicted by Gene Expression

Increased baseline gene expression in the peripheral blood may be associated with improved response to methotrexate, in RA patients.

Tumor Necrosis Factor Inhibitors May Increase Extra-articular RA Risk

Tumor Necrosis Factor Inhibitors May Increase Extra-articular RA Risk

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Predictors for developing ExRA included older age, longer duration of RA, male sex, and positive rheumatoid factor at baseline.

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