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Patients with SLE Higher Risk of Developing Metabolic Syndrome

Patients with SLE Higher Risk of Developing Metabolic Syndrome

More than 25% of SLE patients also have metabolic syndrome.

SHARE Launches Childhood-onset Systemic Lupus Erythematosus Initiative

SHARE Launches Childhood-onset Systemic Lupus Erythematosus Initiative

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The SHARE initiative established guidelines on cSLE, which is a rare disorder.

Complement System A Contributer to Lupus Clinical Manifestations

Complement System A Contributer to Lupus Clinical Manifestations

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Mannose-binding lectin of the complement system may contribute to the development of clinical manifestations in SLE.

Diagnosis and Treatment of Childhood Lupus Nephritis: SHARE Recommendations

Diagnosis and Treatment of Childhood Lupus Nephritis: SHARE Recommendations

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The development of lupus nephritis is associated with significant morbidity and mortality.

B-Cell Depletion Predicts Rituximab Response in Systemic Lupus Erythematosus

B-Cell Depletion Predicts Rituximab Response in Systemic Lupus Erythematosus

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Rituximab non-responders may still be amenable to B-cell targeted therapies, such as ofatumumab or obinutuzumab.

CVD Prevention Counseling Decreases CVD Risk Factor Prevalence in SLE

CVD Prevention Counseling Decreases CVD Risk Factor Prevalence in SLE

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This study finds that a cardiovascular disease prevention counseling program decreases the prevalence of cardiovascular disease risk factors in patients with systemic lupus erythematosus.

Venetoclax Safe, Effective in Women With Systemic Lupus Erythematosus

Venetoclax Safe, Effective in Women With Systemic Lupus Erythematosus

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Use of the anti-apoptotic protein B-cell lymphoma 2 inhibitor venetoclax reduced total lymphocyte and disease-relevant B cells in women with SLE.

SLE: New Candidate Criteria Drafted By Researchers

SLE: New Candidate Criteria Drafted By Researchers

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Researchers have created a set of 21 candidate criteria for SLE as part of a multiphase development of a set of criteria for the disease.

Guidelines for Peri-Op Care in Rheumatic Disease

Guidelines for Peri-Op Care in Rheumatic Disease

These guidelines address the use of antirheumatic drugs for adults with RA, SpA, JIA, and SLE undergoing THA or TKA.

Optimal ANA Cutoff Titer as Entry Criterion for SLE Classification

Optimal ANA Cutoff Titer as Entry Criterion for SLE Classification

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The new approach in development proposes the use of positive indirect immunofluorescence ANA (IIF-ANA) as an entry criterion for SLE classification.

Risk Factors for Depression in Patients With Childhood-Onset Lupus

Risk Factors for Depression in Patients With Childhood-Onset Lupus

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Increased disease activity, poorer physical functioning, and lower education attainment were major predictors for depression in adulthood.

Biomarkers of Pulmonary Arterial Hypertension Risk in SLE

Biomarkers of Pulmonary Arterial Hypertension Risk in SLE

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Meta-analysis supports anti-RNP and anti-Sm antibodies as serological biomarkers of PAH risk in patients with systemic lupus erythematosus.

Patients With Systemic Lupus Erythematosus and Cognitive Dysfunction Prevalence

Patients With Systemic Lupus Erythematosus and Cognitive Dysfunction Prevalence

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MOCA is more effective than the Mini-Mental State Examination at detecting cognitive dysfunction.

Patients With Lupus Have Poor Quality of Sleep, Quality of Life

Patients With Lupus Have Poor Quality of Sleep, Quality of Life

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The majority of patients with systemic lupus erythematosus have poor quality of sleep.

Steroid Dosage as Risk Factor for Osteonecrosis in Patients With SLE

Steroid Dosage as Risk Factor for Osteonecrosis in Patients With SLE

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Cumulative steroid dosage is a risk factor for the development of osteonecrosis.

SLE in Mothers May Lead to Increased Allergy Risk in Offspring

SLE in Mothers May Lead to Increased Allergy Risk in Offspring

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There is an increased risk of allergic conditions in the offspring of mothers with SLE.

Belimumab for SLE: Is Subcutaneous Delivery As Effective as Infusion?

Belimumab for SLE: Is Subcutaneous Delivery As Effective as Infusion?

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As intravenous infusion can pose challenges to patients, the current study sought to evaluate the efficacy of subcutaneous belimumab.

International Panel Releases Guidelines for Biologics Use in Lupus

International Panel Releases Guidelines for Biologics Use in Lupus

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The guidelines were established by a mutidisciplinary group of experts with a goal of optimizing lupus outcomes for all patients.

EULAR Updates Recommendations for Reproductive Planning in SLE

EULAR Updates Recommendations for Reproductive Planning in SLE

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Multidisciplinary experts provide 12 recommendations for the planning and management of pregnancy in systemic lupus erythematosus and/or antiphospholipid syndrome.

Analysis of Incidence Rates of ESRD in Newly Diagnosed SLE

Analysis of Incidence Rates of ESRD in Newly Diagnosed SLE

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An estimate of the incidence rate of end-stage renal disease was identified in a population of patients with newly diagnosed SLE in the Atlanta, Georgia metropolitan area.

Incidence of ASCVD  Increased in African Americans and Young Adults With Inflammatory CTD

Incidence of ASCVD Increased in African Americans and Young Adults With Inflammatory CTD

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CTD is associated with higher prevalence of atherosclerotic cardiovascular disease in African Americans and in young adults.

Cigarette Smoke Exposure Linked to Increased Morbidity in SLE

Cigarette Smoke Exposure Linked to Increased Morbidity in SLE

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Cigarette smoke exposure is associated with increased morbidity in SLE as assessed by SDI score.

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