Systemic lupus erythematosus (SLE)
Complement pathway activation is associated with adverse pregnancy outcomes in women with systemic lupus erythematosus or antiphospholipid antibodies.
Advances in the management of systemic lupus erythematosus have improved quality of life and outcomes for women who are considering pregnancy.
Smoking is associated with risk for development of the anti-double-stranded DNA positive subtype of systemic lupus erythematosus.
The frequency, attribution, clinical, and autoantibody status of patients with lupus who developed cerebrovascular events are reported in this study.
Future research should look to improve perioperative management in people with systemic lupus erythematosus.
At this time, no serological test can distinguish neuropsychiatric events resulting from SLE activity from events resulting from other causes.
The risk for asthma may be increased in children born to mothers with systemic lupus erythematosus during pregnancy.
EULAR and ACR jointly funded and collaborated on creating a set of criteria that can be used to more accurately identify patients with SLE for inclusion in clinical trials.
Current smoking and >10 pack-years of smoking have demonstrated a strong and specific association with an increased risk for occurrence of anti-double-stranded DNA systemic lupus erythematosus.
In patients with SLE, 62.1% did not adhere to their medication regimens and 35% of patients demonstrated a depressed mood.
Identification of the biologic pathways by which psychosocial trauma may increase a woman's risk for autoimmune disorders is critical and may offer greater insight into disease etiology and strategies for prevention.
Drug-induced lupus erythematosus refers to an idiosyncratic side effect of medications with clinical features similar to the autoimmune-driven idiopathic lupus erythematosus.
Research confirmed the increased burden of SLE in black, Asian, and Hispanic women compared with white women.
Hydroxychloroquine Plus Low-Dose Aspirin Reduces Cardiovascular Events in Systemic Lupus ErythematosusJuly 14, 2017
Long-term hydroxychloroquine use, combined with low-dose aspirin, protected against thrombosis in patients with systemic lupus erythematosus.
This condition is associated with serious disease flare complicated by sepsis and a high mortality rate.
Lupus nephritis a risk factor for some, but not all, cardiovascular outcomes in study of patients with SLE.
Influenza vaccination reduced risk of hospitalization, pneumonia, ICU admission, in-hospital dialysis, and death.
A randomized-control trial found that mind-body skills training improved depressive symptoms in patients with SLE.
The institution of an algorithmic approach to diagnostic testing for SLE improved access to specialty care in a safety net system providing health care to the underserved.
The US FDA has approved an update to the prescribing information for all proton pump inhibitors to include risk for cutaneous and systemic lupus erythematosus.
Amylase-trypsin inhibitors (ATIs) found in wheat have been linked to inflammation in the lymph nodes, kidneys, spleen, and brain, and can worsen symptoms of RA, SLE, and MS.
The researchers confirm a relatively high prevalence of significant VHD among patients with SLE and a confirmed association between VHD and aPL positivity.
Targeted IL-6 inhibition with sirukumab did not demonstrate efficacy or acceptable safety in patients with active lupus nephritis concomitantly receiving immunosupprsant therapy.
Researchers found significant disparities in pregnancy complications rates and hospitalization costs among white, black, and Hispanic women with systemic lupus erythematosus
Clinicians and researchers weigh in on the advent of precision medicine for the treatment of SLE.
Analysis of medical records confirms that celiac disease frequently co-occurs with SLE.
S aureus colonization was associated with particular SLE phenotypes.
Although levels of aPL decreased throughout pregnancy, these changes were not found to be associated with changes in adverse pregnancy outcomes.
New study investigates links between elevated BLyS and APRIL levels and response to atacicept treatment.
Panels of urinary biomarkers were shown to be have increased diagnostic power in predicting complete clinical responses when compared with individual biomarkers.
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