Systemic Lupus Erythematosus
Researchers investigated serum IgG anti-MDA expression and associations with disease activity in patients with systemic lupus erythematosus.
Results from the MUSE trial show that lupus low disease activity state attainment in patients with systemic lupus erythematosus is a clinically meaningful disease outcome measure.
Researchers used phenotype-wide association studies to uncover associations in men and women with systemic lupus erythematosus.
Researchers found that disease flare incidence in women with SLE increased during pregnancy and within 3 months postpartum.
No significant differences were observed in the incidence of ESRD and mortality among men vs women with lupus nephritis.
Disease damage in patients with childhood-onset SLE is common, even with relatively short disease durations.
Epratuzumab improved systemic lupus erythematosus disease activity in patients with associated Sjogren syndrome.
Infodemiology can estimate the health-related demands and behaviors of systemic lupus erythematosus.
Researchers examined the proportion of Medicaid patients with systemic lupus erythematosus who receive baseline retinal examinations when initiating treatment with hydroxychloroquine.
In patients with primary antiphospholipid syndrome, the presence of phosphatidylserine/prothrombin complex antibodies is associated with Raynaud phenomenon and migraine.
Data from the CARRA Legacy Registry show disability is common in patients with childhood-onset SLE.
Smoking is associated with risk for development of the anti-double-stranded DNA positive subtype of systemic lupus erythematosus.
Patients with primary antiphospholipid syndrome and systemic lupus erythematosus-associated antiphospholipid syndrome have an almost 2.5-fold risk for development of atherosclerotic plaques in carotid and femoral arteries compared with healthy control patients.
Older patients with SLE are at a low risk for the development of proteinuria.
Lupus low disease activity state has been shown to be achievable and negatively associated with early damage accrual.
Neonatal systemic lupus erythematosus syndrome develops as a result of passively acquired autoimmunity, when autoantibodies produced by the mother cross the placenta, affecting the developing fetus.
Investigators evaluated long-term outcomes with antimalarial use and organ damage, flares, disease activity, glucocorticoid use, and antimalarial associated retinopathy.
"Infodemiology" and "infoveillance" are terms used to describe an emerging approach to public health research, based on Google Trends big data monitoring and data mining.
Virginia Pascual, MD, discusses precision medicine for rheumatic diseases.
The SHARE initiative has formulated evidence-based recommendations for the diagnosis and treatment of lupus nephritis childhood-onset lupus nephritis.
Maternal systemic lupus erythematosus during pregnancy is associated with increased risk for asthma in children.
Switching from 1 antimalarial agent to a second may be beneficial in patients with cutaneous lupus erythematosus.
Rates of SLE mortality have declined, but remain high relative to non-SLE mortality.
Atacicept may be safe and effective for lowering disease activity and severity in patients with active systemic lupus erythematosus.
Anti-ficolin-2 autoantibodies may represent a biomarker for renal manifestations in patients with active systemic lupus erythematosus.
Low vitamin D is linked with later total organ and renal damage in patients with SLE.
EULAR and ACR jointly funded and collaborated on creating a set of criteria that can be used to more accurately identify patients with SLE for inclusion in clinical trials.
Researchers studied how BMI changes would affect disease activity in systemic lupus erythematosus
Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.
The impact of excess adiposity in SLE has not been established, despite obesity being a common comorbidity in SLE.
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