Systemic Lupus Erythematosus

Lymphoma in Patients With Systemic Lupus Erythematosus: Expert Insights

Lymphoma in Patients With Systemic Lupus Erythematosus: Expert Insights

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In this expert interview, Sasha Bernatsky, MD, PhD, and Michelle Petri, MD, MPH, discuss the risk of non-Hodgkin lymphoma in SLE.

SLE in Mothers May Lead to Increased Allergy Risk in Offspring

SLE in Mothers May Lead to Increased Allergy Risk in Offspring

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There is an increased risk of allergic conditions in the offspring of mothers with SLE.

Belimumab for SLE: Is Subcutaneous Delivery As Effective as Infusion?

Belimumab for SLE: Is Subcutaneous Delivery As Effective as Infusion?

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As intravenous infusion can pose challenges to patients, the current study sought to evaluate the efficacy of subcutaneous belimumab.

Genetic Variant Tied to SLE and MS Identified

Genetic Variant Tied to SLE and MS Identified

BAFF variant was likely selected over time as an adaptive response to malaria.

International Panel Releases Guidelines for Biologics Use in Lupus

International Panel Releases Guidelines for Biologics Use in Lupus

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The guidelines were established by a mutidisciplinary group of experts with a goal of optimizing lupus outcomes for all patients.

Relative Risk of Ischemic Stroke Doubled in Systemic Lupus Erythematosus

Relative Risk of Ischemic Stroke Doubled in Systemic Lupus Erythematosus

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A matched cohort study compared the risk of incident stroke in individuals with SLE with individuals without SLE in the general population.

The Handoff: Your Week in Rheumatology News - 4/14/17

The Handoff: Your Week in Rheumatology News - 4/14/17

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This week, a phase III trial for investigational drug voclosporin for lupus nephritis treatment was approved, prolonged insomnia may lead to less robust bone formation — causing osteoporosis and bone fractures — and researchers found that women who drink a moderate amount of alcohol daily have a reduced risk of developing systemic lupus erythmatosus.

Lupus Low-disease Activity State Can Predict Flare-up Risk

Lupus Low-disease Activity State Can Predict Flare-up Risk

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Asia-Pacific Lupus Collaborative's low-disease activity score can predict risk of flare-ups, according to research from a group at Hong Kong University.

Reduced Lupus Risk Linked to Moderate Alcohol Consumption in Women

Reduced Lupus Risk Linked to Moderate Alcohol Consumption in Women

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The study evaluated 2 groups of women from the Nurses' Health Study (NHS) and NHSII cohorts, examining alcohol consumption and the onset of systemic lupus erythematosus.

Systemic Lupus Erythematosus Leads to Lower Quality-of-Life Measures

Systemic Lupus Erythematosus Leads to Lower Quality-of-Life Measures

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Study of patients with systemic lupus erythematosus in China evaluates quality of life measures in several areas.

The Handoff: Your Week in Rheumatology News - 3/24/17

The Handoff: Your Week in Rheumatology News - 3/24/17

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New guidelines for rheumatoid arthritis treatment with DMARDs and money being steered into lupus research highlight this week's The Handoff.

Reduced Psychosocial Reserve Linked to Increased SLE Disease Burden

Reduced Psychosocial Reserve Linked to Increased SLE Disease Burden

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Patients with systemic lupus erythematosus and low self-esteem reported higher levels of anxiety and depression.

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

High-dose Steroids Increase Serious Infection Risk in Pregnant Women With Inflammatory Conditions

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An observational cohort study of 4961 women with completed pregnancies and a recorded diagnosis of systemic inflammatory conditions.

Elevated Disease Markers Identified in Relatives of Patients With Lupus

Elevated Disease Markers Identified in Relatives of Patients With Lupus

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Changes in levels of soluble mediators may predict SLE transition in unaffected relatives of patients.

Lupus Family Planning Recommendations Issued by EULAR

Lupus Family Planning Recommendations Issued by EULAR

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A European League Against Rheumatism writing committee has issued recommendations for family planning for women with systemic lupus erythematosus and antiphospholipid syndrome based on a systemic review.

Lupus: Using Diet and Nutrition to Improve Symptoms and Outcomes

Lupus: Using Diet and Nutrition to Improve Symptoms and Outcomes

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Consuming adequate amounts of the right nutrients, and limiting others, can help relieve symptoms and improve outcomes in patients with systemic lupus erythematosus.

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

Lupus Among Autoimmune Diseases Tied to Subsequent Dementia Risk

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Study reviewed information from 1.8 million individuals in England admitted to a hospital with an autoimmune disease.

The Handoff: Your Week in Rheumatology News - 3/3/17

The Handoff: Your Week in Rheumatology News - 3/3/17

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Connecticut considers rheumatoid arthritis and fibromyalgia for medical marijuana treatment, while Lyme disease-carrying deer ticks continue to invade Michigan. All this and more in this week's edition.

Adults With Lupus More Likely to Have Depression and Anxiety

Adults With Lupus More Likely to Have Depression and Anxiety

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The researchers conducted a systematic review of data from 59 studies.

Researchers Examine Potential Key to Future Lupus Treatments

Researchers Examine Potential Key to Future Lupus Treatments

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Research examined virus-independent activation of MAVS protein in patients with systemic lupus erythematosus.

Drug-Induced Lupus Observed With Adalimumab Treatment For Psoriasis

Drug-Induced Lupus Observed With Adalimumab Treatment For Psoriasis

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Investigators observe patient develop drug-induced lupus while taking biologic treatment for psoriasis.

Lupus Research Grants Available for Post-Graduate Study

Lupus Research Grants Available for Post-Graduate Study

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The Lupus Foundation of America is now accepting applications for 8 grants, with dedicated awards to minority applicants, pediatric research, and research that has an impact on rural areas.

<i>In Vitro</i> Fertilization is Safe and Effective in SLE and APS

In Vitro Fertilization is Safe and Effective in SLE and APS

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Study evaluated the complications and success rates for IVF in women with systemic lupus erythematosus or antiphospholipid syndrome.

Systemic Lupus Erythematosus Increases Incidence of High-Risk HPV

Systemic Lupus Erythematosus Increases Incidence of High-Risk HPV

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Three-year follow-up shows statistically significant increase in cumulative presence of HPV infection.

End-Stage Renal Disease Risk Higher in SLE Patients Hospitalized for Infections

End-Stage Renal Disease Risk Higher in SLE Patients Hospitalized for Infections

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End-stage renal disease is 5-fold more likely to develop in patients with 3 or more infection-related hospitalizations versus none.

Cognitive Dysfunction, Memory Impairment Evaluated by fMRI in Non-Neuropsychiatric SLE

Cognitive Dysfunction, Memory Impairment Evaluated by fMRI in Non-Neuropsychiatric SLE

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Functional MRI imaging in patients with non-neuropsychiatric systemic lupus erythematosus found that defects in spatial working memory and cognitive dysfunction were related to damage in specific neural networks.

Depression in Systemic Lupus Erythematosus Linked to Cardiovascular Disease

Depression in Systemic Lupus Erythematosus Linked to Cardiovascular Disease

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Women with systemic lupus erythematosus and depression were more likely to have increased carotid intima-media thickness compared with those with SLE without depression.

No Increased Risk of CV Death in Cutaneous Lupus Erythematosus

No Increased Risk of CV Death in Cutaneous Lupus Erythematosus

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Patients with cutaneous lupus erythematosus (CLE) were assessed for their risk of cerebrovascular accidents, ischemic heart disease, and peripheral arterial disease.

Efficacy of Targeted Interferon-α Inhibition in SLE

Efficacy of Targeted Interferon-α Inhibition in SLE

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Eligible participants participated in a phase IIb trial of sifalimumab to determine the drug's effect on moderate-to-severe active SLE.

RCT: Mind-Body Training Improves Depressive Symptoms in SLE

RCT: Mind-Body Training Improves Depressive Symptoms in SLE

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A randomized-control trial found that mind-body skills training improved depressive symptoms in patients with SLE.

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