Rheumatology Advisor

LATEST NEWS

Clinicians Positioned to Support Partnerships That Address Community Health

Progressive Skin Fibrosis in SSc Associated With Lung Function Decline

Rituximab Safe, Effective in Patients With Systemic Sclerosis

Increased Risk for Herpes Simplex Virus Infection Noted in Systemic Lupus Erythematosus

Experimental Pain Variability May Predict Response to Drug vs Placebo in OA Clinical Trials

Ixekizumab Effective in Phase 3 Nonradiographic Axial Spondyloarthritis Trial

Loan Forgiveness, Educational Debt May Affect Practice Patterns

Chronic Widespread Pain Prevalent in Ankylosing Spondylitis, Undifferentiated Spondyloarthritis

Coronary Artery Disease More Prevalent in Rheumatoid Arthritis

Comparing Clinical vs Ultrasound Findings of Ankle Pain in Rheumatoid Arthritis

Synovial Biomarkers in Early RA Predict Disease Severity, DMARD Response

Increased Aortic Stiffness in Patients at Risk for Rheumatoid Arthritis

LATEST FEATURES

Immune-Related Adverse Events in Cancer Immunotherapy: The Role of the Rheumatologist

Rheumatologists are expected to play an increasing role in the diagnosis and management of patients with cancer with immune checkpoint inhibitor-related rheumatic diseases.

hospital beds in the hospital hallway

Are Hospital Readmission Reduction Programs Truly Evidence Based?

When politicians attempt to make changes to health policy based on sentiments rather than on evidence-based conclusions, physicians often find themselves trying to meet unrealistic expectations.

CV Risk Assessment Using Deep Learning-Based Tissue Characterization in RA

Researchers found data that showed automated intelligence-based techniques are beneficial in detecting cardiovascular disease caused by the genetic makeup of patients with rheumatoid arthritis.

Periodontal Disease and Rheumatoid Arthritis: How Are They Related?

Rheumatology Advisor interviewed Dr Sofat, who suggests that better control of periodontal disease might improve outcomes in rheumatoid arthritis.

more features >>

OPINIONS

Pete Salzmann, MD, VP, Immunology at Lilly

Rheumatoid Arthritis

Seizing the Opportunity to Create Change in the Rheumatology Field

Effective and affordable treatment options are essential to controlling costs within the rheumatoid arthritis treatment space and delivering value to patients.

Clinician filling out a prescription

Pain Management

The Opioid Epidemic: Why Your Prescribing Habits Matter

If physicians have a genuine interest in acting with beneficence and nonmaleficence, they should recognize that their prescribing habits have significant consequences for their patients.

Doctor and patient concierge medicine.

Practice Management

Reexamining the Role of Concierge Medicine in Primary Care

During the last decade, the number of medical students choosing internal or family medicine has dropped by approximately 80%.

woman wearing a fitbit

Opinion

Wearable Fitness Trackers: Are We Placing Too Much Faith in Them?

The utility and effectiveness of wearable fitness devices are discussed in a clinician’s opinion piece.

Practice Management

Practice Managers Can Help Physician Group Grow, Thrive

Practice managers can either be beneficial to a practice, or add unneeded stress.

CASE STUDIES

Photomicrograph of the kidney

Case Study: Systemic Lupus Erythematosus With Lupus Nephritis and Thrombotic Microangiopathy

By

Yongen Chang, MD, PhD, and Eric Seronick, DO

A 19-year-old woman presents with complaints of progressive shortness of breath, chest pain, and lower extremity edema over the past month.

tent for camping

Case Study: A Syncopal Episode During a Camping Trip

By

George Marzouka, MD

A 52-year-old man presents to the emergency department with dizziness and fatigue after a syncopal episode on a camping trip.

rheumatoid arthritis hands x-ray ulnar deviation

Case Study: Rheumatoid Arthritis Cardiac Manifestations

By

George Marzouka, MD

A 69 year old man presents joint pain (wrists, elbows, hands, and knees) and swelling with no evidence of erosions.

Case Study and Clinical Highlight: Respiratory Failure in a Patient With SLE

By

Corinna Sison, MD Medical Editor

A female patient with systemic lupus erythematosus presents to the emergency department with an 8 week history of dyspnea, dysphonia, and non-productive cough.

Case Study and Clinical Highlight: A Patient With Nephrotic Syndrome and Ankylosing Spondylitis

By

Corinna Sison, MD Medical Editor

AA amyloidosis is a rare but significant complication of ankylosing spondylitis (AS) and may lead to proteinuria and renal dysfunction.

SLIDESHOWS

Patients with RA experience localized and generalized bone loss.2 Data have also shown that patients with well-controlled RA have significantly more bone loss than healthy individuals.4 The pathology of bone loss in RA is multifactorial and complex. The pannus, a proliferation of inflamed synovial tissue, releases several proinflammatory cytokines. Some, such as TNF-α, IL-1, IL-6, and IL-17, are osteoclastogenic and promote bone resorption, partly through upregulation of nuclear factor-kB ligand.1,3,5 They also inhibit anti-osteoclastogenic cytokines.1 Further, TNF-α upregulates proteins that inhibit the Wnt pathway, thus suppressing osteoblast activity.1,3,5 The resulting imbalance in bone remodeling, favoring bone resorption, causes bone loss and inferior bone quality. Immobility and glucocorticoid use, both common in patients with RA, also promote bone loss.1,2 Standard risk factors for bone loss may exacerbate RA-induced bone loss.5

Skeletal Complications in Rheumatoid Arthritis: A Comprehensive Review

Artificial intelligence (AI) may be the key to combating burnout among clinicians. According to a report published in Medical Economics, AI can reduce clinicians’ burdens by recognizing patterns in large amounts of data.4 The Cleveland Clinic notes that “with AI’s continued integration into healthcare, caring for patients has become a matter of working smarter, not harder.”3 Considering burnout and depression often develop in tandem, this is especially welcome news for the medical community.

Predictions in Medicine 2019: What’s Ahead

Derm Dx: Erythematous Rash on the Upper Back

Ischemic stroke is the most common severe neurologic complication of APS. Among 1000 people with APS participating in the Euro-Phospholipid Project, 20% presented with stroke and 11% presented with transient ischemic stroke.2,5 About 13% of patients with stroke are aPL-positive,2 and they are more likely to be younger or female compared with aPL-negative patients.3 More than 20% of strokes in patients <45 years may be related to APS.3 In APS, stroke occurs when a clot forms in an arterial vessel of the brain or when clot or plaque debris travels from another site (usually the heart) to a blood vessel in the brain.2,3 Less common cerebrovascular diseases seen in patients with APS that may increase stroke risk are cerebral venous thrombosis, reversible cerebral vasoconstriction syndrome, acute ischemic encephalopathy (a rare feature of SLE), and Sneddon syndrome.3 To reduce stroke risk, clinicians may want to discuss modifiable risk factors for vascular disease, such as smoking and obesity, with those who are positive for aPL.3 Image Credit: Zephyr/Science Source

Examining the Spectrum of Neurologic Manifestations in Antiphospholipid Syndrome

Anterior vs Posterior Approach in Total Hip Replacement

Browse drugs by:

Brand Generic Disease