Anthony M. Reginato

Does this patient have basic calcium phosphate crystal/hydroxyapatite deposition disease? Basic calcium phosphate (BCP) crystals encompass three different types of calcium crystals: carbonate-substituted hydroxyapatite, octacalcium phosphate, and tricalcium phosphate. Hydroxyapatite (HA) is the most common component of BCP crystals. BCP crystals are usually inert and asymptomatic, but can cause several syndromes due to deposition in…

You’re Reading an Archived Article. Please refer to the updated piece on Calcium Pyrophosphate Deposition Disease (CPPD). Does this patient have calcium pyrophosphate dihydrate crystal deposition disease? Definitions Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is an umbrella term encompassing all instances of calcium pyrophosphate dihydrate (CPP) crystal precipitation in connective tissues seen in asymptomatic…

Does this patient have Gout? Gout is a disease resulting from deposition of monosodium urate (MSU) crystals in the joints and connective soft-tissues in the setting of sustained hyperuricemia (serum uric acid >6.8 mg/dL). Classically, the initial manifestation of gout is acute monoarthritis characterized with abrupt onset of exquisite pain and swelling of the joint…