Cassandra Pardini, PharmD

Suppressed drug metabolism was identified in patients with various inflammatory conditions.

The network meta-analysis compared the effects of 9 osteoporosis drugs on BMD.

The study authors utilized the National Social Life, Health, and Aging Project leave-behind questionnaire to obtain data on a total of 6017 adults over 65 years of age.

Small increases in the risk for statin-associated muscle symptoms were observed for patients on high-intensity therapy.

Current recommendations surrounding the administration of the second COVID-19 vaccine dose to patients who experience an immediate hypersensitivity reaction to the first dose are conflicting.

Tdap vaccination in the recommended 27–36-week window provides the largest benefit.

The patient, who had suffered a traumatic brain injury approximately 8 months prior, presented to the emergency department complaining of increasing dizziness as well as sleepwalking frequency.

Overall, opioids were found to have accounted for the majority of medications used in the ED and prescribed at discharge.

Lenvatinib was associated with the most significant probability of producing all grades of cardiovascular injury and hypertension.

Given that treatment options for RA are rapidly changing, the study authors aimed to summarize information surrounding potential drug-drug interactions with JAK inhibitors in order to help health care providers make informed decisions.

To determine the association between cumulative exposure of potent and very potent TCSs and osteoporosis and MOF risk, study authors utilized the Danish nationwide registries.

To assess the effectiveness of these therapies on pain reduction and quality of life improvement, study authors searched various databases for randomized or quasi-randomized clinical trials that evaluated these outcomes in fibromyalgia patients.

A new case of cutaneous lupus erythematosus or systemic lupus erythematosus could potentially be drug induced.

Early treatment with glucocorticoids may be beneficial for patients hospitalized with COVID-19 who have high levels of inflammation due to the disease.

Colchicine could potentially play a role in the treatment of hospitalized patients with COVID-19.

Prescription fill patterns of medications associated with potential benefits, as well as possible harms, during the COVID-19 pandemic described in new analysis.

The use of immune globulin therapy appears to benefit children who experience acute heart failure caused by coronavirus disease 2019 (COVID-19)-related multisystem inflammatory syndrome, according to the findings of a case series recently published in Circulation.

Recommendations on the management of COVID-19 were recently released by the NIH to help guide clinicians caring for patients with COVID-19.

Allopurinol and febuxostat were found to be associated with a higher risk of hypersensitivity reactions when compared to colchicine, according to the results of a recently published population-based study.

Several treatments were attempted but failed to manage the patient’s conditions, including proton pump inhibitors, topical steroids, a restricted diet, and infliximab (3 doses) for arthritis.

A recently published report presented at the 2019 AIBD Annual Meeting in Orlando, FL, discussed the case of a patient who developed ulcerative colitis (UC) following treatment with Secukinumab for her psoriatic arthritis and highlighted a novel approach for the management of both of her conditions simultaneously.

Compared with intravenous hydrocortisone, IV methylprednisolone appears to be more beneficial as a pre-infusion prophylaxis therapy in patients receiving pegloticase, according to the findings of a recently published review.

According to the findings of a recent review, the Food and Drug Administration rarely disagrees with recommendations made by its advisory committees.

Opioids are commonly prescribed for acute gout management following discharge from the emergency department.

“Migratory polyarthritis secondary to clopidogrel is a diagnosis of exclusion,” the study authors concluded, adding, “Early diagnosis and timely intervention are essential, as the symptoms completely resolve after discontinuing clopidogrel, and the inflammatory markers return to baseline.”

Immune modulators have proven to be effective for rheumatologic diseases by altering the immune system, however, they have also been found to produce a variety of endocrine effects in patients as well.