High-Dose Trivalent Inactivated Influenza Vaccine Improves Seroconversion Rate in RA
A high-dose trivalent vaccine may enhance antibody production against influenza in people with RA.
All articles by Corinna Sison, MD
Assessment of Life Expectancy in Scleroderma-Associated Pulmonary Arterial Hypertension
Patients with scleroderma-associated isolated pulmonary arterial hypertension (SSc-PAH) have a slightly higher mortality risk than patients SSc-PAH with concomitant interstitial lung disease.
One-Year Efficacy of Ixekizumab in Psoriatic Arthritis
WASHINGTON, DC — Treatment of psoriatic arthritis (PsA) with ixekizumab (IXE)—an IgG4 monoclonal antibody—significantly improves arthritis, dactylitis and enthesitis at 52-weeks, according to research presented at the 2016 American College of Rheumatology Annual Meeting. Philip J Mease, MD, at the Swedish Medical Center and the University of Washington, and colleagues conducted a phase 3 study…
Beta-Blockers Decrease Opioid Rx in Comorbid OA, HTN
Beta-blocker use was associated with less joint pain and lower use of opioids in patients with symptomatic, large joint radiographic OA.
Comparative Efficacy of TNF-α Inhibitors Evaluated in AS
In this meta-analysis, the researchers found that all TNF-α inhibitors were more effective at treating AS than placebo in direct comparisons, but no differences in efficacy or safety were found between individual TNF-α inhibitors in indirect comparisons.
Targeted JAK Inhibition Effective RA Treatment in csDMARD-Inadequate Responders
Selective inhibition of JAK1 and JAK2 with baricitinib resulted in clinical improvements in RA symptoms and inhibited joint structural disease progression in patients with active RA who have failed csDMARDs.
Updated EULAR Guidelines for RA CVD Risk Management
The European League Against Rheumatism has released updated management guidelines to address cardiovascular disease risk assessment in patients with rheumatoid arthritis and other inflammatory arthritides.
Predictors of Remission in New-Onset Inflammatory Polyarthritis
An analysis of patients with IP in the Norfolk Arthritis Register found that predictors for a lower likelihood of remission included female sex, baseline higher tender joint count or disability, depression, obesity, and hypertension.
Periodontal Pathogen Antibodies Precede RA Symptom Onset
Antibody concentrations against antigen epitopes of the oral pathogen P gingivalis appear to increase prior to the onset of RA symptoms, suggesting that P gingivalis may be associated with RA pathogenesis.
Specific IL-17A Blockade Reduces PsA Disease Activity
IL-17A blockade resulted in inhibition of the progression of structural joint damage, suggesting that IL-17A plays a key role in PsA pathogenesis.
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