Hannah Dellabella

Hannah Dellabella

All articles by Hannah Dellabella

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Researchers found that testing adalimumab serum concentrations in the last serum sample from patients with rheumatoid arthritis from the Amsterdam Rheumatology and Immunology Center using enzyme-linked immunosorbent assays showed that patients with ≧5.0 μg/mL adalimumab had a lower response rate when switched to etanercept compared with patients who were biologic-naïve. However, researchers believe that a larger study population is required for more detailed results.

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For patients with rheumatoid arthritis (RA), using conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) concomitantly with biologic DMARDs (bDMARDs) is associated with a significantly reduced risk for bDMARD discontinuation because of adverse events (AEs), according to results published in the Journal of Rheumatology. The study included participants from the Ontario Best Practices Research Initiative (OBRI) who…

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The researchers found data that the approximate median time to complete the Routine Assessment of Patient Index Data 3 was 116 seconds vs 35 seconds for the Patient-Reported Outcomes Measurement Information System (PROMIS) and showed comparable results, so they believe that the PROMIS is a way for patients to save time and clinicians to collect other valuable information.

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Participants with early rheumatoid arthritis in the Swedish Pharmacotherapy clinical trial who were treated with methotrexate therapy for 3 months were found to have baseline level biomarkers of low C-reactive protein and leptin with high tumor necrosis factor receptor 1 and vascular cell adhesion molecule 1 that were associated with low disease activity.