Joshua A. Butler

All articles by Joshua A. Butler

Palisaded Encapsulated Neuroma (Neuroma [PEN and traumatic], Solitary Circumscribed Neuroma, and Traumatic Neuroma (Amputation Neuroma)

Are You Confident of the Diagnosis? Neuromas are proliferations of the basic units of peripheral nerves, axons and their surrounding Schwann cells, in roughly equal ratios. There are two major subtypes: palisaded encapsulated neuroma (PEN) also known as solitary circumscribed neuroma, characterized by hamartomatous proliferations of nerve fibers without previous trauma; and traumatic neuroma, also…

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