Natasha Persaud

The prevalence of vertebral fracture was lower among treated than untreated patients.

This is the first study to assess the effect of allopurinol initiation on mortality in patients with CKD and concomitant gout, according to investigators.

Compared with patients who not have gout, patients with gout had increased likelihood of undergoing lower extremity amputations.

A complete renal remission duration of more than 18 months was associated with good pregnancy outcomes and lower odds of lupus nephritis relapse.

Study findings may help to resolve a controversy between rheumatology societies and the American College of Physicians regarding gout management recommendations.

Investigators examined mortality in patients with lupus nephritis who had all stages of chronic kidney disease.

In a study of patients hospitalized with SLE, Black and Hispanic patients and those of other races had higher rates of lupus nephritis compared with White patients, a study found.

Infection-related mortality appears worse for patients with lupus nephritis.

Patients with lupus nephritis should be allow early access to COVID-19 vaccination, according to investigators.

In a survey, more rheumatologists than nephrologists viewed belimumab and voclosporin as a “substantial advance” in lupus nephritis treatment.

Standard therapy for lupus nephritis achieves complete renal response in only 20% to 40% of patients.

Voclosporin acts as an anti-inflammatory agent and also stabilizes podocytes to reduce proteinuria.

Renal response at 6 months strongly predicted belimumab’s durability.

The risk of lupus nephritis flares decreased with belimumab treatment, investigators reported.

Recent approval of new drugs for lupus nephritis and promising therapies on the horizon bode well for the care of patients with the kidney disorder.

The management recommendations for lupus nephritis are poised to change significantly in the coming months, a KDIGO committee revealed.

The current guideline-recommended creatinine-based eGFR equation incorporates a race coefficient that may overestimate eGFR in Black adults and contribute to discordant care.

Investigators examined the urate-lowering effects of febuxostat, allopurinol, and benzbromarone and their association with renal protection in CKD.

Improving access to kidney transplantation for patients with lupus nephritis could significantly reduce their cardiovascular morbidity, according to investigators.

Investigators speculate that a novel target of autoimmunity in LN that affects renal tubular potassium transport results in idiopathic hypokalemia in patients with LN.

Among children on dialysis, those with lupus nephritis were more likely to be hospitalized.

COVID-19 severity at hospital admission predicts complications even in young adults and those without pre-existing health conditions.

Findings support COVID-19 vaccination of patients on dialysis but suggest that a shift in vaccine strategy for kidney transplant recipients may be warranted.

In a small study, 34% of dialysis patients had vertebral fractures, and patients in the highest tertile of parathyroid hormone level had a nearly 3-fold increased risk of these fractures compared with those in the middle tertile.

In a small trial, patients with the highest tertile of IL-6 experienced significantly faster progression of diabetic kidney disease.

The proportion of patients with lupus nephritis achieving renal response with belimumab increased during a 6-month extension study.

Study findings highlight the importance of following the clinical trial vaccine administration protocol in patients receiving hemodialysis, according to investigators.

Chronic inflammation in patients with rheumatoid arthritis might cause kidney damage, according to investigators.

Fewer sudden unexpected deaths occurred among patients who received early renal replacement therapy, investigators reported.

Medicaid patients with SLE or lupus nephritis have worse outcomes compared with privately insured patients, research shows.