Axial Spondyloarthritis
Inflammatory Back Pain and Neuropathic Pain May Affect Axial Spondyloarthritis Outcomes
September 07, 2018Patients with axial spondyloarthritis who have inflammatory back pain or neuropathic pain may have higher pain intensity, pain interference, disease activity, and greater functional limitation compared with individuals with axial spondyloarthritis but without either comorbidity.
Greater Baseline Symptom Burden Linked to Poorer TNFi Response Rates in axSpA
September 05, 2018Patients who reported a greater symptom burden at the start of TNFi treatment had poor response rates and low retention rates.
MR-VIBE More Sensitive for Detecting Erosions in Sacroiliac Joints
August 31, 2018VIBE detected erosions in the sacroiliac joints with higher sensitivity without a loss of specificity and superior reliability compared with a standard T1-weighted sequence.
Gender Differences, Clinical Outcomes of Pain in Axial Spondyloarthritis
August 24, 2018The location and spread of pain in patients with axial spondyloarthritis was different between genders and was related to worse clinical status.
Biologic Therapy Improves Work Productivity in Axial Spondyloarthritis
August 23, 2018Consistent data show that treatment with biologic therapy significantly improves work productivity and activity impairment among patients with axial spondyloarthritis.
Identifying Early Structural Changes in Axial Spondyloarthritis: A Comparison of Scoring Methods
August 14, 2018Investigators compared the performance of different spinal radiographic damage scoring methods in patients with early axial spondyloarthritis.
Comorbid Fibromyalgia Influences Disease Activity, Quality of Life in Axial Spondyloarthritis
August 09, 2018Meeting the criteria for fibromyalgia had a modest effect on disease activity and did not influence the response to TNFi therapy.
Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA
August 06, 2018Depression is common in patients with axSpA and is associated with more severe disease activity and functional impairment.
Differentiating Between axSpA, Degenerative Disease Abnormalities on MRI, Radiographs
July 19, 2018Researchers sought to assess whether it is possible to discriminate between degenerative changes and lesions associated with axSpA.
Adalimumab Continuation Linked to Fewer Flares After Remission in Nonradiographic axSpA
July 12, 2018In patients with nonradiographic axial spondyloarthritis who achieve remission with adalimumab, continued therapy was linked to fewer flares vs treatment withdrawal.
Novel Automated Mobility Measure Yields High Reproducibility in Axial Spondyloarthritis
July 03, 2018Researchers assessed the reproducibility of UCOASMI in clinical practice settings.
Gender Differences in Axial Spondyloarthritis: Comparing Disease Burden and Treatment
June 28, 2018An improved understanding of the gender differences in axial spondyloarthritis can improve disease treatment and reduce disease burden.
ASAS Health Index Valid, Reliable in Axial and Peripheral Spondyloarthritis
June 28, 2018The Assessment of Spondyloarthritis International Society Health Index proved to be valid, reliable, and responsive.
Effects of Maternal axSpA Disease Activity on Pregnancy Outcomes Examined
June 14, 2018A systematic review revealed no signal for increased pregnancy loss in patients with axial spondyloarthritis.
Ustekinumab, TNF Inhibitors Improve 6-Month Outcomes in Psoriatic Arthritis
June 14, 2018Researchers sought to evaluate the efficacy, tolerability, and persistence of TNFi and ustekinumab in patients with psoriatic arthritis initiating first-line, second-line, or third-line biologic DMARDs.
Reduced Structural Damage in Early Axial Spondyloarthritis Linked to Increased IL-31 Levels
June 05, 2018Increased interleukin-31 levels may protect against structural damage in patients with axial spondyloarthritis.
Extended Disease Duration Increases Risk for IBD, Uveitis in Axial Spondyloarthritis
May 31, 2018Axial spondyloarthritis disease duration was associated with higher risk of developing acute anterior uveitis and inflammatory bowel disease, but not psoriasis.
High Rate of Hidradenitis Suppurativa Observed in Patients With Axial Spondyloarthritis
May 29, 2018Hidradenitis suppurativa is more common in patients with axial spondyloarthritis compared with the general population.
Certolizumab Pegol Demonstrates Positive Results in Phase 3 Trial for Nonradiographic Axial Spondyloarthritis
May 17, 2018Results from a phase 3 trial show that certolizumab pegol improves the signs and symptoms of nonradiographic axial spondyloarthritis compared with placebo at 52 weeks.
Incidence of Cardiovascular Events Similar in Rheumatoid Arthritis, Spondyloarthritis
April 27, 2018The incidence of adverse cardiovascular events in patients with RA do not differ significantly compared with those with PsA or axSpA.
Radiographic Sacroiliitis vs MRI Structural Lesions for Axial Spondyloarthritis Classification
April 16, 2018Researchers sought to investigate the utility of adding structural MRI lesions of the sacroiliac joints to the imaging criterion of the ASAS axSpA criteria.
Sustained Clinical, Functional Improvements With Adalimumab in Axial Spondyloarthritis
April 13, 2018Results from the ABILITY-1 study show sustained clinical and functional improvements with adalimumab treatment in nonradiographic axial spondyloarthritis.
Disease Activity in Axial Spondyloarthritis Generally Low, Stable During Pregnancy
April 05, 2018Researchers found that disease activity was highest during the second trimester of pregnancy.
Trabecular Bone Score May Predict Future Vertebral Fracture in Axial Spondyloarthritis
April 04, 2018Researchers found that trabecular bone scores may be predictive of future vertebral fractures in patients with axial spondyloarthritis.
Comorbid Fibromyalgia and Axial Spondyloarthritis: Response to TNF Blocker Therapy
March 22, 2018Researchers sought to confirm whether concomitant fibromyalgia has a negative effect on TNF blocker response.
Adalimumab Reduces Whole-Body MRI Indices of Inflammation in axSpA
March 21, 2018Adalimumab may decrease whole-body magnetic resonance imaging indices of inflammation in both axial and peripheral joints and enthuses in axSpA.
Anti-CD74 Antibodies Have Limited Diagnostic Value in Early Axial Spondyloarthritis
March 20, 2018Anti-CD74 IgG and IgA antibodies have limited value in the diagnosis of early axial spondyloarthritis in younger patients who present with early back pain.
Adherence to Anti-TNF Blocker Recommendations in axSpA Linked to Improved Quality of Life
March 16, 2018Adherence to recommendations for the initiation and continuation of TNF-alpha blocker therapy in patients with axial spondyloarthritis is associated with improved quality of life.
Challenges of Targeting Remission in Axial Spondyloarthritis
March 09, 2018Current guidelines define remission as the absence of clinical and laboratory evidence of significant inflammatory disease, but the tools that are currently available are inadequate to assess clinical remission.
Functional Status in Early Axial Spondyloarthritis: The Role of Spinal Structural Damage
February 08, 2018Results of the GESPIC study found that structural damage in the spine and disease activity were both determinants of functional status and spine mobility in patients with early axial spondyloarthritis.
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