Indications for: AUGMENTIN ES-600 SUSPENSION
Susceptible recurrent or persistent acute otitis media (see full labeling).
Limitations of Use:
Not indicated for the treatment of acute otitis media due to S. pneumoniae with penicillin MIC ≥4mcg/mL.
Take with food. Base dose on amoxicillin component. Due to clavulanic acid component, ES-600 is not interchangable with other susp formulations. <3months: not recommended. ≥3months (<40kg): 90mg/kg per day in 2 divided doses every 12 hours for 10 days. ≥40kg: not recommended.
AUGMENTIN ES-600 SUSPENSION Contraindications:
History of amoxicillin/clavulanic acid-associated cholestatic jaundice/hepatic dysfunction. Ext-rel: Severe renal impairment (CrCl <30mL/min) or hemodialysis.
AUGMENTIN ES-600 SUSPENSION Warnings/Precautions:
Cephalosporin, imipenem, or other allergy: not recommended. Monitor blood, renal, and hepatic function in long-term use. Monitor closely if skin rash develops; discontinue if lesions progress. Hepatic dysfunction. Mononucleosis. Elderly (consider monitoring renal function). Labor & delivery. Pregnancy (Cat.B). Nursing mothers.
AUGMENTIN ES-600 SUSPENSION Classification:
Broad-spectrum penicillin + β-lactamase inhibitor.
AUGMENTIN ES-600 SUSPENSION Interactions:
May cause false (+) glucose test with Clinitest, Benedict's or Fehling's soln. Probenecid potentiates amoxicillin. May potentiate oral anticoagulants (monitor). May antagonize oral contraceptives.
Diarrhea, nausea, abdominal pain, rash, urticaria, vomiting, vaginitis; anaphylaxis, severe cutaneous adverse reactions (eg, SJS, TEN, DRESS, AGEP).
Ext-rel tabs—contact supplier; Tabs 875mg—20; Susp 125mg/5mL, 250mg/5mL—75mL, 100mL, 150mL; Chew tabs—contact supplier; Susp ES-600 600mg/5mL—50mL, 75mL, 100mL, 125mL, 150mL, 200mL