Anemias:

Indications for: INFED

Iron deficiency where oral therapy is intolerable or unsatisfactory response.

Adults and Children:

<4mos: not recommended. Give by IV or deep IM inj into upper outer quadrant of buttock only. Administer 0.5mL test dose first; if no signs/symptoms of anaphylactic-type reactions, may give full therapeutic dose. ≥4mos: Iron deficiency anemia: determine total dose based on hemoglobin and body weight (see full labeling). Iron replacement for blood loss: Replacement iron (in mg) = blood loss (in mL) × hematocrit. See full labeling.

Boxed Warning:

Risk for anaphylactic-type reactions.

INFED Warnings/Precautions:

Monitor for anaphylactic-type reactions, esp. in patients with history of drug allergies, asthma; have epinephrine available. Avoid large IV doses; higher incidence of adverse events. Severe hepatic impairment. Avoid during acute phase of infectious kidney disease. Dialysis. Cardiovascular disease. Rheumatoid arthritis. Iron overload. Neonates. Pregnancy. Nursing mothers.

INFED Classification:

Hematinic.

INFED Interactions:

Concomitant ACE inhibitors may increase the risk for anaphylactic-type reactions. May falsely elevate serum bilirubin or decrease serum calcium levels.

Adverse Reactions:

Nausea, vomiting, chest pain, backache, hypersensitivity, dyspnea, hypotension, pruritus, flushing, dizziness; anaphylactic reactions (may be fatal; even if test dose was tolerated), cardiovascular events, inj site reactions, others; possible sepsis in neonates.

Generic Drug Availability:

NO

How Supplied:

Vials (2mL)—10

Pricing for INFED

2ml of 50mg/ml vial (Qty: 6)
Appx. price $197
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