Miscellaneous hematological agents:
Indications for Nimodipine Capsules:
To improve neurological outcome of subarachnoid hemorrhage from ruptured intracranial berry aneurysms, regardless of post-ictus neurological condition.
Take on empty stomach. 60mg every 4 hours for 21 consecutive days. Start within 96 hours of subarachnoid hemorrhage. If oral therapy is not feasible, may extract capsule contents into a syringe and give via in situ NG tube, then flush tube with normal saline. Hepatic impairment: 30mg every 4 hours; monitor.
Not for IV or other parenteral administration (may be fatal). Hepatic impairment. Monitor BP, heart rate. Pregnancy (Cat.C). Nursing mothers: not recommended.
Calcium channel blocker (CCB).
May potentiate other calcium channel blockers. Potentiated by cimetidine.
Decreased blood pressure, GI upset, headache, bradycardia, flushing, edema, rash; rare: intestinal pseudo-obstruction and ileus.
Formerly known under the brand name Nimotop.