Gout

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Diet Less Important Than Genes for High Serum Urate Levels

Diet Less Important Than Genes for High Serum Urate Levels

Diet explains little of the variation in serum urate levels in the general population, while genetic factors make a greater contribution.

Ultrasound Can Reveal Renal Medulla Urate Deposits in Tophaceous Gout

Ultrasound Can Reveal Renal Medulla Urate Deposits in Tophaceous Gout

Ultrasound examination may be used to detect crystal deposition in the renal medulla in patients with tophaceous gout.

Examining Referral Patterns for DECT in Diagnosis, Management of Gout

Examining Referral Patterns for DECT in Diagnosis, Management of Gout

Researchers examined the use of dual-energy computed tomography gout imaging in clinical practice from 2007 to 2016.

Monosodium Urate Measured With DECT Predicts Risk for Flare in Gout

Monosodium Urate Measured With DECT Predicts Risk for Flare in Gout

The extent of monosodium urate burden measured with dual-energy computed tomography can predict the risk for disease flares in patients with gout.

Routine Knee, Metatarsophalangeal Joint Examination May Improve Gout Diagnosis

Routine Knee, Metatarsophalangeal Joint Examination May Improve Gout Diagnosis

Researchers evaluated the distribution of ultrasound features of lower-limb joints and the risk factors of tophus in patients with gout.

Clinical Gout-Related Benefits Not Demonstrated With Lesinurad Combination Therapy

Clinical Gout-Related Benefits Not Demonstrated With Lesinurad Combination Therapy

Although a combination of lesinurad 200 mg and xanthine oxidase inhibitor therapy was effective and well-tolerated among patients with gout, clinical gout-related benefits were not improved.

Patients With Obstructive Sleep Apnea Have Increased Risk for Gout

Patients With Obstructive Sleep Apnea Have Increased Risk for Gout

People with obstructive sleep apnea continued to be at higher risk of developing gout after the first year of obstructive sleep apnea diagnosis.

Gout Attack Risk Lowered With Interleukin-1ß Blockade

Gout Attack Risk Lowered With Interleukin-1ß Blockade

Inhibition of IL-1ß with canakinumab significantly decreased gout attack risk at all baseline serum uric acid (SUA) levels and without changing SUA levels.

Limited Evidence for Teratogenicity of Allopurinol Use During Pregnancy

Limited Evidence for Teratogenicity of Allopurinol Use During Pregnancy

Researchers found insufficient evidence of teratogenicity for allopurinol taken prior to or during pregnancy.

Patients With Gout Have Lower Prevalence of Colorectal Cancer

Patients With Gout Have Lower Prevalence of Colorectal Cancer

The 10-year prevalence of colonoscopy-documented colorectal cancer was 0.8% among gout patients vs 3.7% among osteoarthritis patients.

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