Higher Prevalence of Echocardiographic Abnormalities in Patients With PsA and RA Than General Population

Close Up of Ecocardiography report (ECG) showing irregular heartbeat
Researchers determined echocardiographic parameters in patients with rheumatoid arthritis and psoriatic arthritis in comparison with healthy individuals.

The following article is a part of conference coverage from the American College of Rheumatology (ACR) Convergence 2021, being held virtually from November 3 to 10, 2021. The team at Rheumatology Advisor will be reporting on the latest news and research conducted by leading experts in rheumatology. Check back for more from the ACR Convergence 2021.


Echocardiographic abnormalities may be higher in patients with psoriatic arthritis (PsA) and rheumatoid arthritis (RA) compared with the general population, according to study results presented at the American College of Rheumatology (ACR) Convergence 2021, held virtually from November 3 to 10, 2021.

In the current case-control study, the researchers evaluated cardiac abnormalities using echocardiography in 36 patients — 19 in each group (PsA, RA, and control). Patients with PsA and RA were matched by age, sex, and comorbidities with healthy control individuals. All participants underwent transthoracic echocardiograms.

A total of 36 patients (age range, 40-75 years) were included in the study. The 3 study groups were demographically similar. Statistically significant differences were found between the PsA, RA, and control groups in diastolic dysfunction (52.6% vs 52.6% vs 5.3%, respectively; P =.002), mild mitral valve regurgitation (84.2% vs 53.6% vs 10.5%, respectively; P =.001), mild pulmonary valve regurgitation (68.4% vs 10.5% vs 0%, respectively; P =.001), and prevalence of abnormal left ventricular geometry (68.4% vs 63.2% vs 21.1%, respectively; P =.006).

The researchers concluded, “This study shows the high prevalence of echocardiographic alterations in [patients with] PsA compared [with] the general population, of the same magnitude as patients with RA. We emphasize the value of an echocardiogram for a complete cardiovascular evaluation and early detection of cardiac abnormalities in these patients.”


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Rodriguez-Romero A, Azpiri-Lopez J, Galarza-Delgado D, et al. Higher prevalence of echocardiographic abnormalities in psoriatic arthritis and rheumatoid arthritis patients compared to controls. Presented at: ACR Convergence 2021; November 3-10, 2021. Abstract 1308.