General Rheumatology

Glucocorticoids Plus Tocilizumab May Improve Respiratory Outcomes in COVID-19-Related Cytokine Storm Syndrome

Researchers assessed the effect of treatment with glucocorticoids and tocilizumab in patients with severe COVID-19-associated cytokine storm syndrome.

Decrease in Incidence of Hip Fractures From 1970 to 2010

The incidence of hip fracture decreased from 1970 to 2010 in the US.

Effect of Glucocorticoids in COVID-19 Varies With CRP Levels

The impact of glucocorticoid treatment on patients with COVID-19 varies according to C-reactive protein levels.

ACR Updates COVID-19 Guidance for the Management of Adult Patients With Rheumatic Diseases

The American College of Rheumatology updated its COVID-19 guidance for the management of adult patients with rheumatic diseases.

Patients With COVID-19 With High Inflammation Levels May Benefit From Steroid Therapy

Early treatment with glucocorticoids may be beneficial for patients hospitalized with COVID-19 who have high levels of inflammation due to the disease.

Low Hemoglobin A1c, BMI Associated With Increased Fracture Risk in Type 2 Diabetes

Low hemoglobin A1c and low body mass index are associated with higher risk for bone fracture in individuals with type 2 diabetes.

Ad5-Vectored COVID-19 Vaccine Immunogenic in Healthy Adults

The nonreplicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine appears safe and induces immune responses.

Iloprost May Be Useful in the Treatment of COVID-19 Vasculopathy

Authors of this report assessed the role of iloprost in the management of COVID-19-related vasculopathy.

Early Data Show Investigational ChAdOx1 nCoV-19 Vaccine Safe, Immunogenic

Interim results from the phase 1/2 COV001 trial evaluating the vaccine candidate ChAdOx1 nCoV-19 (AZD1222) showed that vaccination led to strong immune responses.

Rheumatic Disease May Increase Risk for Severe COVID-19 Outcomes

Researchers investigated the clinical characteristics and outcomes of COVID-19 infection in patients with vs without rheumatic disease.

Sarilumab Linked to Faster Recovery in Severe COVID-19 With Hyperinflammation

This is the first study to describe the safety of IL-6 blockade with intravenous sarilumab in patients with COVID-19 pneumonia with systemic hyperinflammation.

Lower Mortality With Tocilizumab in Mechanically Ventilated Patients With COVID-19

For patients with COVID-19 requiring mechanical ventilation, tocilizumab is associated with improved survival.

Patients With Arthritis Require More Support While Sheltering-in-Place During COVID-19

The Norfolk Arthritis Register has released an interim report on the impact of COVID-19 restrictions on people living with inflammatory arthritis.

Cancer Screening Strategies in Rheumatic Diseases: Expert Perspectives

Experts highlight the need for cancer screening strategies in patients with rheumatic diseases.

American College of Rheumatology Releases Position Statements for Telemedicine Use

The American College of Rheumatology has issued a set of position statements for the use of telemedicine in the management of patients with rheumatic diseases.