General Rheumatology

Ultrasound May Be Superior to Conventional Radiography for CPPD Diagnosis

Ultrasound demonstrated better diagnostic capacity than conventional radiography to diagnose calcium pyrophosphate deposition disease.

Managing Ocular Disorders in Inflammatory Joint Disease: An Interdisciplinary Approach

Ocular symptoms can be the dominant clinical manifestation of rheumatic disease in some cases and knowledge of these relationships can improve the care of both the eye and the joint disease.

Lymphoma Associated With High Parotid Uptake and Pulmonary Lesions on PET-CT in Primary Sjogren Syndrome

A lymphoma diagnosis was associated with focal lung lesions or maximum parotid gland uptake on PET-CT in primary Sjogren syndrome.

Vaccination Guidelines Released for Patients With Immune-Mediated Disorders

A multidisciplinary group of clinicians has developed evidence-based clinical guidelines regarding the vaccination of individuals exposed to immunosuppressive therapies.

Smoking Status Inversely Linked to Primary Sjogren Syndrome

Data show that current smoking status was inversely associated with primary Sjogren syndrome.

Phosphatidylinositol 3-Kinase Delta: A Potential Target Pathway in Sjogren Syndrome

Data show that the phosphatidylinositol 3-kinase delta isoform pathway is active in Sjogren syndrome.

PAH: An Under-Recognized Complication of Adult-Onset Still’s Disease

PAH is an under-diagnosed complication of adult-onset Still disease.

Risk Factors for Repeat Surgery Identified in Septic Arthritis of the Hip

Investigators identified risk factors for repeat surgical intervention after initial arthrotomy for presumed septic arthritis of the hip.

DAPT Effective, Safe for Prophylaxis of Arterial Thrombosis in Antiphospholipid Syndrome

Dual antiplatelet therapy may be effective for the prophylaxis of recurrent arterial thrombosis in patients with antiphospholipid syndrome.

Efficacy of Low-Dose Interleukin-2 Examined Across Autoimmune Diseases

Researchers assessed the safety, biologic, and clinical effects of low-dose interleukin-2 across 11 individual diseases chosen to represent the whole spectrum of autoimmune or inflammatory chronic diseases.

TNFi Treatment Patterns Examined Among Pregnant Women

Using a validated claims-based algorithm, study authors identified pregnancies among women 15-54 years of age from the US Sentinel System between January 1 2004 and September 30 2015.

Synovial Biopsy Analysis in Rheumatic Disease: Consensus Items Developed by EULAR, OMERACT

A set of analysis items has been developed by the EULAR Synovitis Study Group and the OMERACT Synovial Tissue Biopsy Group for the analysis of synovial biopsies in rheumatic diseases.

Assessing Comorbidity Prevalence Among Patients With Polymyalgia Rheumatica

Researchers conducted a systematic review to examine the existing literature on comorbidities associated with PMR.

Immunogenicity of Golimumab Validated Using Novel Anti-Drug Antibody Detection Assay

Antidrug antibody incidence was higher using drug-tolerant vs original enzyme immunoassays in patients treated with golimumab.

Single-Dose Prefilled Autoinjector for Actemra Approved

Genentech announced that the FDA has approved ACTPen autoinjector for Actemra as a new formulation for adults with moderate to severe active RA.