HealthDay News – The American College of Rheumatology (ACR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria do not distinguish between patients with and without major internal disease in subacute cutaneous lupus erythematosus (SCLE), according to research published in the Journal of the American Academy of Dermatology.

Janice Tiao, from the Michael J. Crescenz Philadelphia Department of Veterans Affairs Medical Center, and colleagues conducted a retrospective analysis of 107 patients with SCLE to determine how patients with SCLE/SLE meet the ACR and SLICC criteria.

The researchers found that using both sets of criteria, patients with SCLE/SLE were more likely to have oral ulcers, positive anti-double-stranded DNA antibodies, and positive antinuclear antibody test findings than those with only SCLE. 


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Using the SLICC criteria, patients with SCLE/SLE were more likely to have low complement. A statistically insignificant increase was seen in individuals meeting the SLIC criteria.

Summary and Clinical Applicability

“Most patients with SCLE who formally meet criteria for SLE do so based on the laboratory and mucocutaneous criteria. Neither the ACR nor SLICC criteria distinguish patients with SCLE and major internal disease from patients with SCLE without major internal disease,” the authors conclude. 

“Clinicians should not rely on these criteria to identify patients with subacute cutaneous lupus erythematosus with significant systemic disease.”

Reference

Tiao J, Feng R, Carr K, Okawa J, Werth VP. Using the American College of Rheumatology (ACR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria to determine the diagnosis of systemic lupus erythematosus (SLE) in patients with subacute cutaneous lupus erythematosus (SCLE). J Am Acad Dermatol. 2016;74(5):862-9.