Topics

TOPICS

ANKYLOSING SPONDYLITIS

Metagenomic Sequencing Reconfirms Key Role of Gut Microbiome in AS Pathogenesis

Researchers evaluated the microbial characteristics driving ankylosing spondylitis pathogenesis, and they examined the effects of tumor necrosis factor inhibitor therapy on the microbiome.

Chronic Kidney Disease More Common Among Men vs Women With Ankylosing Spondylitis

Researchers assessed and compared the risk for chronic kidney disease in men and women with ankylosing spondylitis in China.

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FIBROMYALGIA

Higher Rates of Chronic Pain and Mood Disorders in Patients With Fibromylagia

Recently updated diagnostic criteria for fibromyalgia that reduce the underdiagnosis in men had not been implemented during these studies.

Daytime Physical Activity May Affect Sleep in Patients With Fibromyalgia

Patients with fibromyalgia suffer from chronic pain, which limits physical activity and is associated with disturbed sleep. However, the relationship between physical activity, pain, and sleep is unclear.

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GOUT

Dual-Energy CT Alone May Have Best Overall Accuracy for Gout Diagnosis

Study authors examined the accuracy of dual-energy computed tomography vs ultrasound, or their combination, for the diagnosis of gout.

Assessing Gout Lesions Using a Novel, Semi-Quantitative Ultrasound Scoring System

Study authors aimed to develop a new ultrasound definition and a semi-quantitative ultrasound scoring system for gout lesions.

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LYME DISEASE

New Guidelines for the Management of Lyme Disease

The Infectious Diseases Society of America, American Academy of Neurology, and American College of Rheumatology provided new clinical practice guidelines for Lyme disease prevention, diagnosis, and treatment.

No Increased Risk for Psychiatric Disorders in Patients With Lyme Disease

In order to investigate the risk of psychiatric disease, the percentage of psychiatric hospital inpatient and outpatient contacts, and the receipt of prescribed psychiatric medications among patients in Denmark with Lyme neuroborreliosis was compared with individuals in a matched comparison cohort.

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CONNECTIVE TISSUE DISEASE

Case Report: Stickler Syndrome Presents With Rare Ophthalmologic Manifestations

When systemic signs are not evident, ophthalmologists play a major role in diagnosis.

Anticoagulation Improves Outcomes in Idiopathic PAH, Not CTD-PAH

Systemic anticoagulation was found to improve quality-adjusted life years among patients with idiopathic pulmonary arterial hypertension but not among those with connective tissue disease-associated pulmonary arterial hypertension.

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OSTEOARTHRITIS

Opioid-Related Costs Estimated at $14 Billion for Knee OA

The total lifetime opioid-related costs generated by symptomatic knee osteoarthritis (SKOA) in the United States are $14.0 billion.

Radiographic Hip OA Increased, But Pain Decreased, After 10 Years

This study explored, the natural course of hip osteoarthritis in patients with first-time hip complaints by tracking their symptoms, physical functioning, and radiographic osteoarthritis features over time.

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OSTEOPOROSIS

FSH Levels in Older Postmenopausal Women Affect Bone and Body Composition

The objective of this study was to investigate the associations between endogenous FSH levels and BMD, BMA, and body composition in older adults, independent of estradiol and testosterone levels.

Topical Corticosteroid Use and Osteoporosis Risk Examined

To determine the association between cumulative exposure of potent and very potent TCSs and osteoporosis and MOF risk, study authors utilized the Danish nationwide registries.

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PAIN MANAGEMENT

Aerobic Exercise in Chronic Low Back Pain May Provide Similar Relief to Low-Dose Morphine

Researchers tested whether aerobic exercise training altered morphine analgesic responses or reduced morphine dosages necessary for adequate analgesia.

Home-Based Virtual Reality Effectively Helps Reduce Low Back Pain Symptoms

Researchers conducted a randomized controlled trial of people with chronic low back pain to evaluate outcomes associated with therapeutic virtual reality treatment.

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PRACTICE MANAGEMENT

AstraZeneca COVID-19 Vaccine Easy to Update in Response to Variants

A COVID-19 vaccine still awaiting US Food and Drug Administration approval may prove to be a powerful weapon in fighting the pandemic.

Text Message System Useful for Monitoring Postoperative Opioid Use

A text message system can monitor postoperative opioid use and shows that many prescribed opioid tablets are unused.

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PSORIATIC ARTHRITIS

Similar Rates of Depression and Anxiety Plus Depression With Apremilast vs Other Drugs in Psoriatic Arthritis

Apremilast used for the treatment of psoriasis or psoriatic arthritis is not associated with a high risk of incident treated depression, anxiety, or anxiety plus depression.

Case Highlights Novel Approach to Treatment of Ulcerative Colitis, Psoriatic Arthritis

A recently published report presented at the 2019 AIBD Annual Meeting in Orlando, FL, discussed the case of a patient who developed ulcerative colitis (UC) following treatment with Secukinumab for her psoriatic arthritis and highlighted a novel approach for the management of both of her conditions simultaneously.

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RHEUMATOID ARTHRITIS

Severe Type 2 Diabetes With Insulin Resistance May Complicate RA

Rheumatoid arthritis and osteoarthritis patients can experience poorly controlled severe type 2 diabetes, say French researchers who suggest considering targeting insulin resistance through treatment for joint and systemic inflammation.

Treatment to Lower RA Disease Activity Feasible in Pregnancy

Low disease activity and remission are feasible goals for women with rheumatoid arthritis (RA) cared for with a modern treatment approach during pregnancy.

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SPONDYLOARTHRITIS

Prevalence of Nonradiographic Sacroiliitis Low Among Patients With Psoriatic Arthritis

Researchers assessed the prevalence of nonradiographic sacroiliitis in patients with psoriatic arthritis, using pelvic radiographs and MRI of sacroiliac joints.

Assessing Health-Related Quality of Life in Early Psoriatic Arthritis vs Early Rheumatoid Arthritis

Researchers evaluated the health-related quality of life in patients with early psoriatic arthritis compared with those with early rheumatoid arthritis and a general population.

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