Switching Patterns Examined for Newly Initiated TNFi Therapy in Ankylosing Spondylitis
Data show that two-thirds of patients with ankylosing spondylitis did not remain on their index TNFi therapy 2 years after treatment initiation.
Topics
TOPICS
ANKYLOSING SPONDYLITIS
Long-Term Exposure to TNFi Therapy May Not Affect Fertility in Men With Spondyloarthritis
Pregnancy and offspring outcomes were reassuring in couples where men with spondyloarthritis (SpA) were exposed to tumor necrosis factor inhibitors (TNFi), according to results from a study published in The Journal of Rheumatology. Researchers conducted a multicenter prospective study of 202 men with SpA who were exposed to TNFi therapy for a minimum of 12…
FIBROMYALGIA
Fibromyalgia May Soon Be Reliably Diagnosed By Blood Test
Fibromyalgia is notoriously difficult to diagnose, but new research suggests that may soon change.
Fibromyalgia Frequently Misdiagnosed, Study Says
Investigators compared clinician- and criteria-based diagnosis of fibromyalgia to spot potential diagnostic misclassification of the disease.
GOUT
Similar Clinical Presentations Found in Prosthetic Joint Infection, CPPD After Joint Implantation
Researchers conducted a case series to examine the demographics, presentation, management, and outcomes in patients with post-implant calcium pyrophosphate deposition disease.
Gout Linked to Increased Risk for Chronic Kidney Disease
Chronic kidney disease is 3 times more likely to develop among individuals with vs without gout, according to a large retrospective cohort study.
LYME DISEASE
Facts About Lyme Disease: 6 Myths You May Encounter With Your Patients
Myths about lyme disease may present a barrier to prompt diagnosis and treatment. As a clinician, you may encounter these 6 misconceptions.
Climate Change Expected to Lead to Rise in Lyme Disease
Rising temperatures are expected to increase the number of cases of Lyme disease in the United States by more than 20% by mid-century.
CONNECTIVE TISSUE DISEASE
Acute Iloprost Inhalation Improves RVEF in PAH-Associated Connective Tissue Disease
Acutely inhaled iloprost improves right ventricular function in terms of RV volume, right ventricular ejection fraction, and RV stroke volume in patients with IPAH and PAH associated with connective tissue disease.
Connective Tissue Disease-Associated Interstitial Lung Disease: Unmet Needs and Challenges
The American College of Rheumatology and Association of Physicians of Great Britain and Ireland have highlighted unmet needs and challenges of connective tissue disease-associated interstitial lung disease.
OSTEOARTHRITIS
Daily Walking Levels Not Associated With Pain in Knee Osteoarthritis
Knee pain was not associated with daily walking levels in mild to moderate knee osteoarthritis.
Tramadol as First-Line Therapy for OA May Be Associated With Greater Mortality
Treating osteoarthritis in older patients with tramadol vs nonsteroidal anti-inflammatory drugs may be associated with an increased mortality rate during the year following treatment initiation.
OSTEOPOROSIS
Zoledronate, Teriparatide Do Not Negatively Affect Carotid Intima-Media Thickness
Treatment with zoledronate or teriparatide for a year did not affect intima-media thickness of the carotid arteries in postmenopausal women with osteoporosis.
Elderly Men May Be Undertreated for Osteoporosis
Elderly men were significantly undertreated for osteoporosis compared with elderly women.
PAIN MANAGEMENT
Opioid Prescriptions Dropped for New Users From 2012 to 2017
Many providers stopped initiating opioid therapy from July 2012 to December 2017.
Four-to-Seven-Day Opioid Prescription Likely Sufficient for Acute Pain Treatment
An opioid supply for seven or fewer days might be sufficient for most patients seen in primary care settings for acute pain who appear to need opioid analgesics.
PRACTICE MANAGEMENT
Underreporting of Study Cohort Sex Distribution Common in Biomedical Research
A large-scale bibliometric analysis underscores a lack of sex-related reporting in biomedical research, despite efforts to include more women in health-based studies.
Limiting the Documentation of Patient Immigration Status in Medical Records
This commentary examines physician options for documenting immigration status considering ethical, legal, and historical circumstances when caring for stigmatized populations during changing political landscapes.
PSORIATIC ARTHRITIS
Disease Burden, Characteristics of Psoriatic Arthritis Examined
Researchers evaluated the prevalence, treatment patterns, disease characteristics, and comorbid diseases among people in Denmark with psoriatic arthritis.
Screening Tool Identifies Psoriatic Arthritis in Patients With Psoriasis
The investigators sought to evaluate the risk for possible undiagnosed psoriatic arthritis in patients with psoriasis.
RHEUMATOID ARTHRITIS
Power Doppler Perfusion Phenotype in RA May Be Dependent on ANCA Status
Power Doppler perfusion phenotype was dependent on anti-citrullinated peptide antibody status, but not on rheumatoid factor status.
Assessing Economic Effects of Cycling vs Swapping After Initial TNFi Failure in RA
Investigators reviewed economic analyses comparing cycling TNFi with swapping with another therapy in patients with rheumatoid arthritis who did not respond to initial TNFi therapy.
SPONDYLOARTHRITIS
Xipere Under FDA Review for Macular Edema Associated With Uveitis
Clearside Biomedical announced that the Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for Xipere (triamcinolone acetonide ophthalmic suspension) for Suprachoroidal Injection for the treatment of macular edema associated with uveitis.
Yutiq Now Available for Chronic Noninfectious Posterior Segment Uveitis
It is designed to release fluocinolone acetonide, a corticosteroid, at an initial rate of 0.25mcg/day.
SYSTEMIC LUPUS ERYTHEMATOSUS
Belimumab Demonstrates Long-Term Safety, Efficacy in Systemic Lupus Erythematosus
Belimumab was well tolerated with no new safety concerns, and efficacy was maintained through 13 years of treatment.
Predictors of Remission, Low Disease Activity State Identified in SLE
Researchers examined predictors of remission and low disease activity state in systemic lupus erythematosus.
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