In a systematic review and meta-analysis, authors assessed the safety and efficacy of Janus kinase (JAK) inhibitors in the treatment of ankylosing spondylitis.
The approval was based on data from the phase 2/3 SELECT-AXIS 1 and the phase 3 SELECT-AXIS 2 trials.
Using quantitative CT, researchers studied the associations between vertebral bone mineral density, strength, and syndesmophytes in ankylosing spondylitis.
Researchers studied the association between the presence of syndesmophytes and facet joint ankylosis in patients with radiographic axial spondyloarthritis receiving low-dose CT for 2 years.
Researchers studied the percentage of patients who continued to have minimal disease activity after dose-interval prolongation with etanercept.
Researchers assessed the long-term effect of ixekizumab on radiographic changes in the spine in patients with radiographic axial spondyloarthritis.
Researchers assessed the prevalence of previously undiagnosed axial spondyloarthritis in patients with acute anterior uveitis and chronic back pain.
Researchers studied the association between IL-18 serum levels and cardiovascular risk and disease activity in patients with ankylosing spondylitis and psoriatic arthritis.
Researchers evaluated the factors associated with decreased spinal mobility and whether poor mobility predicted response to anti-TNF therapy in patients with axial spondyloarthritis.
Researchers analyzed pain catastrophizing in patients with rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis from a biopsychosocial perspective.