Gout

Azathioprine May Increase Pegloticase Responsiveness in Chronic Refractory Gout

Researchers determined the effect of azathioprine on the frequency of chronic refractory gout among patients who had persistent urate lowering from pegloticase therapy.

Genetic Data May Increase Diagnostic Efficiency for Rheumatic Disease

Converting genotype information into an interpretable probability value for five different inflammatory arthritis-causing diseases could potentially improve the diagnostic efficiency of rheumatic disease.

Allopurinol Not Associated With Increased All-Cause Mortality in Gout

Researchers evaluated the association between allopurinol use and mortality in patients with gout.

Hyperuricemia and Kidney Disease May Be Predictors of Subsequent Flares in Patients With Gout

Researchers examined the changes in the presentation of incident gout in the last20 years and determined risk for subsequent gout flares after an initial gout attack.

Serum Urate Does Not Have a Causal Effect on Gout Comorbidity Risk, According to Mendelian Randomization Studies

Researchers reviewed the causal relationships between gout, hyperuricemia, and associated comorbidities.

Fewer Side Effects With Naproxen vs Low-Dose Colchicine in Gout Flare Treatment in Primary Care

Researchers compared the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care.

Higher Prevalence of Cardiovascular Disease Events in Hyperuricemia and Gout

A study of patients at a community-based nephrology practice found a higher cardiovascular disease prevalence with hyperuricemia or gout.

Evaluating the Treatment of Acute Gout Flares in the Emergency Department

Investigators addressed the treatment of acute gout flares in the emergency department.

Gout May Be a Risk Factor for Aortic Stenosis Progression

Aortic stenosis was found to worsen more frequently in patients with vs without gout.

Serum CA72-4 Elevated in Gout, Predicts Future Flares in Patients With Gouty Arthritis

Researchers studied serum CA72-4 expression in patients with gout, and verified the hypothesis that CA72-4 was a predictor of future flares in gouty arthritis.