Gout

Gout Common in the US Dialysis Population

New analysis suggests that gout prevalence is 21% among patients on peritoneal dialysis and 13% among those on hemodialysis.

Pegloticase May Improve Uncontrolled Gout in Kidney Transplant Recipients

Investigators report findings from the PROTECT study assessing the efficacy and safety of pegloticase for uncontrolled gout among kidney transplant recipients.

Increased Spinal Monosodium Urate Deposition Among Individuals With Gout

Investigators used dual-energy computed tomography to assess the extent of spinal monosodium urate deposition among patients with gout.

Allopurinol Noninferior to Febuxostat in the Treatment of Gout

Researchers studied the comparative efficacy and safety of urate-lowering therapy – allopurinol vs febuxostat – in the treatment of gout.

Association Between Diet and Genetic Predisposition in Risk for Incident Gout Among Women

Researchers studied the association between genetic predisposition and diet on risk for incident gout among women.

Urate-Lowering Therapy Not Renoprotective When Kidney Function is Normal

New findings complement previous research showing no renoprotective effect of urate-lowering therapy in patients with chronic kidney disease.

Gout Risk Factors, Outcomes in Dialysis Population Characterized

Some 15% of patients receiving dialysis in the United States have a gout diagnosis, according to a recent study.

Urate-Degrading Enzyme Fast Tracked for Hyperuricemia With Gout and CKD

ALLN-346 is an investigational, first-in-class, nonabsorbed, orally-administered enzyme that breaks down urate in the gastrointestinal tract.

Hyperinsulinemic Diet May Increase Risk for Gout Among Women Older Than 30 Years

In a prospective study, researchers analyzed the association between insulin-related dietary indices and risk for incident gout among US women older than 30 years.

Concomitant Immunomodulatory Therapy Improves Pegloticase Persistence in Gout

Researchers assessed pegloticase persistence associated with concomitant immunomodulatory drug use in patients with uncontrolled gout.