Gout

Guideline-Concordant Gout Therapy Associated With Improved Arterial Function, Reduced Inflammation

Researchers assessed whether initiating guideline-concordant gout therapy improved arterial function and reduced inflammation.

Gout May Be Associated With Increased Risk for Epilepsy

Researchers determined the association between gout and epilepsy and the risk for epilepsy in patients with gout.

Colchicine Is a Cost-Effective Option for Preventing Gout Flares During Allopurinol Initiation

Researchers performed a cost-effectiveness analysis for colchicine prophylaxis in preventing gout flares during allopurinol initiation.

Increased Risk for Erectile Dysfunction in Patients With Gout

Researchers investigated the association between gout and the risk for erectile dysfunction.

Clinical Benefit Observed With Colchicine in Hospitalized Patients With COVID-19

Colchicine could potentially play a role in the treatment of hospitalized patients with COVID-19.

Updated 2020 American College of Rheumatology Gout Management Guidelines

The American College of Rheumatology developed guidelines for the management of gout, including use of urate-lowering therapy, flare treatment, and lifestyle and medication recommendations.

Azathioprine May Increase Pegloticase Responsiveness in Chronic Refractory Gout

Researchers determined the effect of azathioprine on the frequency of chronic refractory gout among patients who had persistent urate lowering from pegloticase therapy.

Genetic Data May Increase Diagnostic Efficiency for Rheumatic Disease

Converting genotype information into an interpretable probability value for five different inflammatory arthritis-causing diseases could potentially improve the diagnostic efficiency of rheumatic disease.

Allopurinol Not Associated With Increased All-Cause Mortality in Gout

Researchers evaluated the association between allopurinol use and mortality in patients with gout.

Hyperuricemia and Kidney Disease May Be Predictors of Subsequent Flares in Patients With Gout

Researchers examined the changes in the presentation of incident gout in the last20 years and determined risk for subsequent gout flares after an initial gout attack.