Gout

Metagenomic Analysis Shows That the Gut Microbiome May Have a Role in Gout

Researchers of a metagenomic analysis assessed the taxonomic and functional signatures of the gut microbiome in gout and its association with clinical parameters and response to therapeutic interventions.

No Difference Between Early and Late Allopurinol Initiation for Acute Gout Flare

Researchers compared the time to complete resolution of acute gout flare between early and late allopurinol initiation.

Evidence-Based Strategies Needed to Improve Outcomes for Patients Hospitalized With Gout – An Interview With Dr Brian LaMoreaux

In an interview, Brian LaMoreaux, MD, MS, discusses the need for evidence-based strategies to improve outcomes for patients hospitalized with gout.

Increased Risk for Cardiovascular Disease in Patients With Concomitant Gout and Psoriasis

Using a population-based cohort, researchers assessed the effects of gout on risk for cardiovascular disease in patients with psoriasis.

Urate-Lowering Therapy Associated With Decreased Gout Flare Risk

Patients with asymptomatic hyperuricemia who achieved serum uric acid levels of 6.0 mg/dL or less while on urate-lowering therapy had fewer gout flare episodes, a study found.

Novel Risk Stratification Tool Identifies Patients at High Risk for Inpatient Gout Flare

Researchers developed and validated a gout flare risk stratification tool for patients with gout who were hospitalized for nongout conditions.

Hyperuricemia Increases Risks for Cardiovascular and All-Cause Mortality

Each 1 mg/dL rise in uric acid level was significantly associated with a 21% and 10% increased risk for cardiovascular and all-cause mortality, respectively, a study found.

DECT-Based MSU-Coded Plaques in Peripheral Arteries Similar Among Patients With and Without Gout

Researchers characterized peripheral vascular plaques that were color-coded as monosodium urate deposition by DECT, and assessed their association with MSU crystal burden in soft tissues.

Hyperuricemia and Gout Do Not Raise Dementia Risk

Hyperuricemia and gout may be associated with a lower risk for Alzheimer disease.

Case Report: Ibrutinib Induces Acute Gout Flare of Bilateral First MTP Joints in Patient With Chronic Lymphocytic Leukemia

A case study of a patient who developed an acute gout flare of bilateral first metatarsophalangeal joints after initiating treatment with ibrutinib for chronic lymphocytic leukemia.