A study conducted in Taiwan is the first to show that hyperuricemia is as risky as diabetes in contributing to ESKD and death risk in patients with stage 3 to 5 CKD.
Colchicine, a plant-derived alkaloid, has a broad range of anti-inflammatory effects that interfere with neutrophil function, according to investigators.
Investigators compared the long-term effects of febuxostat on arterial stiffness and atherosclerosis in patients with hyperuricemia and gout.
Nearly 24% of patients with advanced CKD, including those on dialysis, have gout, according to a study.
Researchers determined risk for gout flares and the effect of colchicine prophylaxis on flares following COVID-19 vaccination.
John Botson, MD, provides his perspective on including immunodulatory therapy in combination with pegloticase and encourages clinicians to evolve their standard of care in the treatment of uncontrolled gout.
Improvement observed in estimated glomerular filtration rate in kidney transplant recipients treated with allopurinol for elevated uric acid.
The mechanism by which hyperuricemia increases SHPT risk is not completely understood.
The sBLA submission is supported by data from the phase 4 MIRROR trial.
Four healthy diets were linked to a reduced risk for new-onset gout in women. Diet selection can be made based on patient preference and comorbidities.