Use of Opioid Prior to TKA Associated With Worse Post-Op Pain

HealthDay News — Patients taking opioids before total knee arthroplasty (TKA) may have greater pain after the procedure, according to a study published in the May 17 issue of the Journal of Bone & Joint Surgery.

The research included 156 patients who underwent TKA. Their average age was 66. Of those patients, 23% received at least 1 opioid prescription before their surgery.

The team found that mean preoperative Pain Catastrophizing Scale scores were greater among opioid users versus non-users (15.5 vs 10.7 points; P =.006). In adjusted analyses, the researchers found that the opioid group had a mean 6-month reduction in Western Ontario and McMaster Universities Osteoarthritis Index score of 27.0 points, compared with 33.6 points in the non-opioid group (P =.008).

“Patients who used opioids prior to TKA obtained less pain relief from the operation,” the authors wrote. “Clinicians should consider limiting pre-TKA opioid prescriptions to optimize the benefits of TKA.”

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Smith S, Bido J, Collins J, et al; Impact of Preoperative Opioid Use on Total Knee Arthroplasty Outcomes. JB&JS. May 17, 2017; 99(10)803-808. doi:10.2106/JBJS.16.01200