Osteoporosis

New Treatment Approved for Osteoporosis With High Risk for Fracture

By

Steve Duffy

The Company is currently conducting a comparative study with the aim of having the treatment designated as a therapeutic equivalent to Forteo.

Factors Predict Low Bone Mineral Density in Pediatric Blood Cancer

Low bone mineral density (BMD) is common in childhood leukemia and lymphoma survivors.

Medicare Spends More Than $6 Billion on Secondary Fractures

Medicare could save billions of dollars if secondary fractures could be prevented with improved osteoporosis screening.

Comparative Efficacy of Medications for Glucocorticoid-Induced Fracture Prevention

A meta-analysis found that teriparatide and denosumab may be the most efficacious therapy for prevention of glucocorticoid-induced vertebral fractures.

Reduced Mobility From Bone Bridge Formation Affects Low BMD in Ankylosing Spondylitis

Researchers conducted this study to determine whether bone bridge formation was correlated with low bone mineral density in patients with ankylosing spondylitis.

Patient Characteristics Predict BMD Response to Bisphosphonates After Denosumab Cessation

Patients with greater BMD improvement after 1 year of denosumab are more likely to lose BMD after the transition to alendronate therapy in the second year.

Positive Patient Experience With Abaloparatide in Osteoporosis

The study, presented at the American Society for Bone and Mineral Research 2019 Annual Meeting, described the experience of patients who initiated treatment with abaloparatide.

Improved Safety Outcomes With Twice-Weekly vs Once-Weekly Teriparatide in Osteoporosis

Researchers investigated the safety and efficacy of twice-weekly 28.2 μg teriparatide compared with once-weekly 56.5 μg teriparatide in Japanese patients with osteoporosis.

High-Dose Teriparatide Plus Denosumab Increases Bone Mineral Density in Osteoporosis

For postmenopausal women with osteoporosis, combined treatment with teriparatide 40 μg and denosumab can increase spine and hip bone mineral density more significantly than standard combination therapy.

Genetically Increased Serum Calcium Not Linked With Improved BMD, Reduced Fracture Risk

Researchers assessed the effect of genetically predicted higher serum calcium levels on bone mineral density and the risk for fracture, using Mendelian randomization.

Bone Loss Likely After Prophylactic Bilateral Salpingo-Oophorectomy

Premenopausal women who undergo prophylactic bilateral salpingo-oophorectomy are especially prone to postoperative bone loss, which may be mitigated by hormone replacement therapy.