Pain Management

Duloxetine Does Not Alleviate Pain in Chronic Osteoarthritis

For patients with chronic osteoarthritis (OA) pain, duloxetine added to usual care has no effect compared with usual care alone.

Guidance Offered for Managing Pain in Patients With Cancer and Opioid Use Disorder

The researchers deemed it appropriate to continue buprenorphine-naloxone with three times-daily dosing for patients with OUD taking buprenorphine-naloxone.

Differential Threat and Safety Learning in the Context of Chronic Back Pain

By

Jessica Nye, PhD

Pain-related threat and safety learning are altered in the setting of chronic back pain.

Gene Therapy Gets Fast Track Status for Pain Associated With Knee Osteoarthritis

By

Brian Park, PharmD

XT-150 is a locally injectable non-viral therapy expressing interleukin (IL)-10v, a proprietary modified variant of IL-10.

High Attrition Rates Challenge Buprenorphine Efficacy in Patients With OUD

By

Emily Pond

Study data published in Neuropsychiatric Disease and Treatment outline the primary factors affecting attrition in buprenorphine treatment for opioid use disorder.

Protocol May Identify Candidates for Neuromodulation Therapies for Pain

A protocol could identify candidates who do not require formal in-person psychological assessment for workup of neuromodulation therapies for pain.

Stronger Opioids Not More Effective for Fractures Managed Surgically

This study found no evidence that stronger opioids were superior to milder opioids for subacute pain.

Low-Quality Evidence for Intradiscal Biologics for Low Back Pain

Current published research supporting the use of intradiscal mesenchymal stem cells and PRP for discogenic back pain is of low quality.

Office-Based Methadone Treatment May Improve Outcomes in Opioid Use Disorder

Investigators conducted a scoping review to determine outcomes among patients with opioid-use disorder who received treatment with methadone in an office-based setting.

Strong Opioids No Better for Pain After Surgery for Fracture

Among patients with surgically managed orthopedic fractures, treatment of pain with strong opioid medication is not superior to milder medication.

FDA Approves Virtual Reality System to Treat Chronic Back Pain

The FDA reports that EaseVRx uses the principles of cognitive behavioral therapy (CBT) and other behavioral therapy techniques to reduce pain and pain interferences.

Trends of Buprenorphine Misuse in the United States Between 2015 and 2019

Buprenorphine misuse was trending downward between 2015 and 2019 among American adults with an opioid use disorder.

Pilates, McKenzie Therapy, and Functional Restoration More Effective Than Others in Reducing Chronic Low Back Pain

Study authors conducted a systematic review and meta-analysis to determine the effect of different exercise treatments on pain intensity in adults with chronic low back pain.

FDA to Review Acetaminophen-Ibuprofen IV Combination for Postoperative Pain

Maxigesic is a combination of acetaminophen 1000mg and ibuprofen 300mg for IV infusion.

Cognitive Behavioral Therapy Intervention Beneficial for Adults With Chronic Pain Conditions

For adults with chronic pain conditions receiving long-term opioid therapy, a CBT intervention produces modest, but sustained, reductions in measures of pain and pain-related disability.