Scleroderma

Intracarpal Ozone vs Methylprednisolone for Carpal Tunnel Syndrome in Patients With Systemic Sclerosis

Researchers compared the clinical efficacy of ozone vs methylprednisolone intracarpal injection on pain, functional status, and nerve conduction in patients with carpal tunnel syndrome due to systemic sclerosis.

Ventricular-Arterial Coupling From 3D Echocardiography May Predict Systemic Sclerosis Prognosis

Researchers evaluated the role of ventricular-arterial coupling from 3D echocardiography in predicting clinical outcomes in patients with systemic sclerosis.

Cardiac Axis Deviation in Systemic Sclerosis-Related Pulmonary Hypertension

Study investigators assessed whether cardiac axis deviation may indicate cardiac function abnormalities, allowing for predictions of disease severity and mortality.

Systemic Hypertension Diminishes Left Ventricular Contractility in Patients With Systemic Sclerosis

Using echocardiographic speckle-derived global longitudinal strain, researchers determined the effect of hypertension on left ventricular contractility in patients with systemic sclerosis.

Multifaceted Mental Health Interventions Assessed for Anxiety Symptoms in SSc During COVID-19

Researchers assessed the effects of the SPIN-CHAT program on anxiety symptoms and other mental health outcomes in patients with systemic sclerosis during the COVID-19 pandemic.

Tocilizumab Preserves Lung Function in Early Systemic Sclerosis

Tocilizumab prevents progression of interstitial lung disease in patients with early systemic sclerosis (SSc).

Meta-Analysis Assesses Safety and Efficacy of Rituximab in Patients With Systemic Sclerosis

Authors of a meta-analysis aimed to systematically assess the safety and efficacy profile of rituximab in patients with systemic sclerosis.

Review of Global Incidence and Prevalence of Systemic Sclerosis

Study authors conducted a systematic review and meta-analysis on the incidence and prevalence of systemic sclerosis.

B-Cell Depletion Therapy May Be Safe, Effective for Systemic Sclerosis-Associated Pulmonary Arterial Hypertension

Researchers assessed the safety and efficacy of B-cell depletion for systemic sclerosis-associated pulmonary arterial hypertension.

Tocilizumab Approved for the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease

The FDA has approved Actemra® (tocilizumab; Genentech) subcutaneous injection for slowing the rate of decline in pulmonary function in SSc-ILD.