Scleroderma

Recommendations for Nailfold Capillaroscopy in Assessment of Raynaud Phenomenon and Systemic Sclerosis

A panel of experts in the field of capillaroscopy and microcirculation published a consensus view on standardizing capillaroscopic image acquisition and analysis.

Inflammatory Arthritis in Localized Scleroderma May Be Less Likely to Respond to Traditional Therapies

Researchers determined the characteristics of inflammatory arthritis in children with localized scleroderma and their response to treatment regimens.

Phosphorylated STAT3 Highly Expressed in CD4+ Cells of Patients With Scleroderma

Researchers evaluated the phosphorylated (activated) form of STAT3 in peripheral blood mononuclear cells in patients with systemic sclerosis.

Digital Ulcers Reduce Quality of Life, Increase Clinical and Economic Burden in Systemic Sclerosis

Researchers evaluated the frequency and clinical characteristics of systemic sclerosis-related digital ulcers, and associated direct healthcare costs, quality of life, and survival.

Systemic Sclerosis Risk May Involve Specific HLA Alleles, Autoantibodies

Researchers investigated the potential association between HLA alleles, autoantibodies, and environmental triggers in the pathogenesis of systemic sclerosis.

Systemic Sclerosis May Be Associated With Risk for Gastrointestinal Bleeding

Investigators examined how systemic sclerosis may predict long-term risk for gastrointestinal bleeding, including the bleeding of upper and lower gastrointestinal tracts.

EHR-Based Algorithms With Billing Codes and Clinical Data Can Identify Systemic Sclerosis

Researchers developed and validated EHR-based algorithms that use billing codes and clinical data to identify patients with systemic sclerosis in the EHR.

Hyaluronic Acid and Platelet-Rich Plasma May Be an Efficient Alternative in Scleroderma

Researchers evaluated the response of patients with scleroderma to filler injections of hyaluronic acid together with platelet-rich plasma.

Systemic Sclerosis May Be Caused by Common Pathologic Clusters in Different Tissues

Researchers investigated the common and tissue-specific pathways involved in the different tissues of patients with systemic sclerosis.

Factors Influencing Improved Survival in Systemic Sclerosis-Associated PAH

Pulmonary arterial hypertension with systemic sclerosis associated-survival improved over time among patients aged 70 years or younger, but not among the elderly.