Spondyloarthritis

Study Supports Bimekizumab for Nonradiographic Axial Spondyloarthritis

The ongoing phase 3 BE MOBILE 1 study compared the efficacy and safety of bimekizumab to placebo in adults with active nr-axSpA.

Early Screening and Management of Cardiovascular Risk Factors Important in Psoriatic Arthritis and Ankylosing Spondylitis

Authors of the systematic review and meta-analysis aimed to determine the all-cause and cause-specific mortality in psoriatic arthritis and ankylosing spondylitis, based on available literature.

Significant Improvements Seen With Bimekizumab in Ankylosing Spondylitis Trial

The ongoing phase 3 BE MOBILE 2 study compared the efficacy and safety of bimekizumab to placebo in 332 adults with active ankylosing spondylitis.

Two Doses of mRNA COVID-19 Vaccine Required to Induce Robust Immune Response in Patients With Inflammatory Joint Diseases

Researchers assessed the immune response of patients with rheumatoid arthritis and seronegative spondyloarthritis to mRNA COVID-19 vaccination after the first and second dose.

Oral Lesions Among Patients With Spondyloarthritis May Indicate Inflammatory Bowel Disease

Investigators sought to identify oral clinical manifestations due to oral mucosa changes associated with IBD among patients with spondyloarthritis without a diagnosis of IBD.

Tofacitinib Approved for Active Ankylosing Spondylitis

The approval was based on data from a phase 3 study which evaluated tofacitinib in adults with active AS who had an inadequate response to at least 2 NSAIDs.

Case Study Describes Success With Alternative Therapies in Patient With Ankylosing Spondylitis

In a case study, Dr de Carvalho describes the successful use of alternative and complementary medicine in a patient with ankylosing spondylitis after cessation of adalimumab therapy.

Anti-IL-23 Therapy Effective in Improving Axial Inflammation in PsA, But Not axSpA?

Authors of a viewpoint discuss the lack of efficacy of anti-IL-23 therapy for axial spondyloarthritis, but the benefits of these medications in improving back pain symptoms induced by axial inflammation in psoriatic arthritis.

Extraskeletal Manifestations in Patients With Axial Spondyloarthritis Associated With Worse Clinical Outcomes

Researchers studied the prevalence and 4-year incidence of acute anterior uveitis, inflammatory bowel disease, and psoriasis, and explore the associations between extraskeletal manifestations and clinical disease outcomes in axial spondyloarthritis.

Similar Gut Microbiome Signature Among Patients With Axial Spondyloarthritis and Related Immune-Mediated Diseases

Researchers observed a shared gut microbiota signature for patients with axial spondyloarthritis and its related immune-mediated diseases.