Case Study: Systemic Lupus Erythematosus With Lupus Nephritis and Thrombotic Microangiopathy
A 19-year-old woman presents with complaints of progressive shortness of breath, chest pain, and lower extremity edema over the past month.
Systemic Lupus Erythematosus
SYSTEMIC LUPUS ERYTHEMATOSUS
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Clinical Trials in Childhood-Onset Systemic Lupus Erythematosus: Next Steps and Future Directions
Access to medications for childhood-onset systemic lupus erythematosus is currently limited, partly because of a lack of high-quality evidence from clinical trials. -
The Role of Viral Infections and Vaccines in the Pathogenesis of Antiphospholipid Syndrome
Recent evidence links specific bacterial, viral infections, and vaccination to the development of APS, but these associations are not clear-cut. -
Improving Medication Adherence With Drug Monitoring in SLE
Therapeutic drug monitoring may be useful to help clinicians assess nonadherence in patients with SLE. -
Are Adverse Pregnancy Outcomes Associated With Accelerated Cardiovascular Events in SLE?
The risk factors for accelerated cardiovascular disease among young women with SLE remain unclear, with multiple studies producing conflicting results. -
Managing Cognitive Dysfunction in Systemic Lupus Erythematosus
The pathogenic pathways of SLE-related cognitive dysfunction are yet to be fully elucidated, but vasculopathy, antibody-mediated neurotoxicity, impairments in cytokine signaling, and complement abnormalities have been proposed as contributing factors. -
PAH-Associated Connective Tissue Diseases: A Case for Separating SSc, SLE
Recent evidence suggests that systemic sclerosis and SLE in pulmonary arterial hypertension should be considered separate diseases. -
Clinician Roundtable: Improving Quality of Life in Systemic Lupus Erythematosus
Quality of life measurements capture unique information about systemic lupus erythematosus that are not included in disease activity or damage evaluations. -
Addressing Racial Disparities in Systemic Lupus Erythematosus Treatment
Racial disparities have been observed in the disease course and outcomes of African Americans with SLE compared with white patients with SLE. -
Expert Insight: Using Infodemiology to Fill Knowledge Gaps in SLE
Infodemiology can estimate the health-related demands and behaviors of systemic lupus erythematosus.
LATEST NEWS
In-Hospital Maternal Mortality Rates Decreased in Pregnancies With Lupus
In-hospital maternal mortality decreased from 1998 to 2015 in systemic lupus erythematosus (SLE) and non-SLE pregnancies, with a greater decline for SLE pregnancies.
Sex-Based Evaluation of Systemic Lupus Erythematosus and Quality of Life
According to the results of a new study, the health and quality of life of people living with systemic lupus erythematous varies by age and sex, especially in the reproductive age groups.
Diastolic Blood Pressure Variability Linked to CV Events in SLE
Visit-to-visit variability in diastolic blood pressure was highly associated with cardiovascular events in patients with systemic lupus erythematosus.
Differences of Nonscarring Alopecia in Systemic Lupus Erythematosus
Investigators review the various clinical patterns and trichoscopic, histopathological, and direct immunofluorescence characteristics of nonscarring alopecia in patients with systemic lupus erythematosus and confirm its link to disease activity.
Anti-NR2 Antibodies May Serve as a Diagnostic Tool for Fatigue in SLE
The study offered an objective measurement for patients with SLE complaining about fatigue in routine clinical practice.
Lupus Linked to Poor Outcomes Post-Primary Total Hip Arthroplasty
Lupus was independently associated with a higher risk of implant infection, transfusion, and healthcare utilization post-THA during the index hospitalization.
Examining Total Knee Arthroplasty Outcomes in Patients With Lupus
Investigators evaluated whether patients with lupus have more complications and/or healthcare use than patients without lupus after primary total knee arthroplasty.
Managing Thrombotic Thrombocytopenic Purpura in Pediatric SLE
Researchers recommended performing lactate dehydrogenase level and blood smear testing in patients with renal and neurological symptoms.
Epidemiologic Study Compares SLE Manifestations in Different Racial Groups
Investigators examined racial/ethnic differences in manifestations of lupus and in the timing and risk of developing severe manifestations.
Lupus Manifestations Appear to Differ by Race, Ethnicity
Clinical manifestations of systemic lupus erythematosus (SLE) vary by racial and ethnic groups.
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