Standardized mortality ratios of observed-to-expected deaths are increased for patients with SLE and are especially high for Asians and Hispanic/Latinos.
Study authors evaluated the incidence of SARS-CoV-2 infections in patients with systemic lupus erythematosus and the effect of treatment discontinuation on disease activity.
Despite the disappointing results of randomized controlled trials such as LUNAR, targeting B cells remains an attractive option in patients with lupus nephritis.
In this case study, the authors highlighted the importance of tuberculous arthritis in the differential diagnoses of patients with persistent ankle swelling.
Based on new findings from a study of patients with systemic lupus erythematosus, investigators suggest revising current guidelines to expand kidney biopsy indications to include isolated proteinuria of any grade.
Researchers evaluated the safety, mechanism of action, and preliminary efficacy of rituximab and cyclophosphamide followed by belimumab in the treatment of refractory lupus nephritis.