Cognitive Impairment Common in SLE, Has Limited Impact on Quality of Life
Researchers evaluated the prevalence and impact of cognitive impairment on quality of life in patients with SLE.
Systemic Lupus Erythematosus
SYSTEMIC LUPUS ERYTHEMATOSUS
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Arterial Health Predicts Cardiovascular Disease Risk in Patients With SLE
Researchers studied the relationship between the total burden of arterial plaque and cardiovascular disease risk in patients with systemic lupus erythematosus. -
Skin That Appears “Normal” Involved in Cutaneous Lupus Erythematosus
For patients with cutaneous lupus erythematosus, normal-appearing skin is a type I interferon-rich, prelesional environment. -
Autoantibody Profiles Shown to Predict High Risk for SLE
Researchers measured autoantibody profiles of serum samples to predict patients who may develop systemic lupus erythematosus. -
SLE Survival Rates Improving, But Lupus Nephritis Risk High Among Non-White Patients
Researchers investigated the patient factors that affect risk for mortality and lupus nephritis among patients with SLE. -
Bowman’s Capsule Rupture Linked to Poor Prognosis in Lupus Nephritis
The integrity of Bowman’s capsule may play a role in the progression of lupus nephritis, according to investigators. -
Anti-Smith Antibodies Are an Important Part of Systemic Lupus Erythematosus Classification Criteria
Study authors discussed the characteristics of the Smith antigen, its role in SLE classification, and the test methods available to detect them. -
Asymptomatic Coronary Artery Disease More Prevalent in Those With vs Without SLE
Study authors collected available data to measure the prevalence of asymptomatic coronary artery disease, assessed by CT angiography, in patients with SLE. -
Belimumab May Reduce Organ Damage in SLE, Lupus Nephritis
Belimumab is a monoclonal antibody that inhibits B-lymphocyte stimulator. -
What Is the Impact of Flare Severity on Quality of Life in Patients With SLE?
Researchers evaluated the impact of flares on health-related quality of life of patients with systemic lupus erythematosus, using data from the Almenara Lupus Cohort
LATEST NEWS
Risk Factors Determined for Pediatric-Onset Discoid and Systemic Lupus Erythematosus
Researchers assessed risk factors and characteristics of a pediatric population with discoid lupus erythematosus and systemic lupus erythematosus.
Infection Risk Varies by Lupus Nephritis Induction Therapy
Adverse effects of induction therapies for lupus nephritis may limit their use.
Clinical Biomarkers of Lupus Nephritis Activity Unreliable
Proteinuria and estimated glomerular filtration rate cannot accurately distinguish between ongoing inflammatory injury and chronic kidney damage in lupus nephritis, investigators pointed out.
High Sensitivity, Low Specificity of EULAR/ACR 2019 Criteria for Childhood-Onset SLE
Researchers compared the sensitivity and specificity of the EULAR/ACR 2019 classification criteria with prior classification criteria among patients with childhood-onset systemic lupus erythematosus.
Performance of Antinuclear Antibody Immunoassays in Systemic Lupus Erythematosus Compared
Researchers aimed to understand the value of antinuclear antibody detection and testing among patients with systemic lupus erythematosus by comparing the performance of 3 available ANA assays.
SLE Diagnosed During Hospitalization Associated With Higher Disease Activity, Damage, and Death
Researchers aimed to study the outcomes of patients with systemic lupus erythematosus diagnosed during hospitalization.
Racial Disparities Seen in Adverse Renal Outcomes for Pediatric Lupus
Proportion of admissions with adverse renal outcomes decreased from 2006 to 2019, but racial disparities persisted
Belimumab Plus Standard Therapy Shows Safety, Efficacy in Systemic Lupus Erythematosus
Researchers assessed the safety and efficacy of belimumab plus standard therapy in the treatment of systemic lupus erythematosus.
Tacrolimus May Be an Alternative to Cyclosphosphamide in Lupus Nephritis Therapy
In a study, the calcineurin inhibitor tacrolimus proved to be noninferior to intravenous cyclophosphamide.
Remission and Low Disease Activity State Improve Health-Related Quality of Life in SLE
Researchers investigated the effect of remission and lupus low disease activity state on health-related quality of life in patients with systemic lupus erythematosus.
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