Examining Hospitalization, Mortality Trends Among Adult Patients With Systemic Lupus Erythematosus
Study authors analyzed all indications for adult systemic lupus erythematosus hospitalizations and reasons for in-hospital mortality.
Systemic Lupus Erythematosus
SYSTEMIC LUPUS ERYTHEMATOSUS
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Is There a Correlation Between IL-6 and SLE Disease Activity?
What is the link between the pro-inflammatory cytokine interleukin-6 (IL-6) and systemic lupus erythematosus (SLE)? Patients with SLE often have elevated levels of serum IL-6, but is there a direct correlation between this and the disease activity of SLE? In a study published in Clinics, a team of researchers reviewed 24 studies published between 1996… -
Aspirin Plus Heparin May Prevent Recurrent Miscarriage in Women With Antiphospholipid Syndrome
Researchers compared and evaluated pharmacologic interventions for the prevention of recurrent miscarriage in women with antiphospholipid syndrome. -
New Study Supports Voclosporin Use in Lupus Nephritis
Pooled analyses from 2 clinical trials show that voclosporin, a novel calcineurin inhibitor, is safe and effective in managing lupus nephritis. -
Lung Involvement in Systemic Lupus Erythematosus Linked to Higher Inpatient Mortality
Lung involvement during hospitalization for systemic lupus erythematosus may be associated with greater inpatient mortality. -
Mycophenolate Mofetil vs Cyclophosphamide in the Induction Treatment of Lupus Nephritis
Researchers evaluated the efficacy and safety of the induction treatment with mycophenolate mofetil and cyclophosphamide for lupus nephritis. -
Low Prevalence of Neuropsychiatric Lupus in Patients With Psychosis With Positive Antinuclear Antibodies
Researchers determined the prevalence of neuropsychiatric systemic lupus erythematosus in patients with psychosis with positive antinuclear antibodies. -
Outcomes of SLE in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura related to SLE may not cause worse outcomes compared with primary immune-mediated TTP. -
New SLE Classification Criteria Perform Well in Early Disease and Across Sexes, Ethnicities
Researchers evaluated the performance of 2019 EULAR/ACR classification criteria for systemic lupus erythematosus, with regard to disease duration, sex, and race/ethnicity. -
Newly Diagnosed SLE Could Potentially Be Drug Induced
A new case of cutaneous lupus erythematosus or systemic lupus erythematosus could potentially be drug induced.
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Belimumab Plus Standard Therapy Improves Renal Outcomes in Patients With Active Lupus Nephritis
Researchers evaluated the safety and efficacy of belimumab plus standard therapy in patients with active lupus nephritis.
Anifrolumab May Reduce Skin Disease Severity in Patients With Active Systemic Lupus Erythematosus
Researchers evaluated the effect on skin-specific systemic lupus erythematosus disease activity using data pooled from the TULIP-1 and TULIP-2 trials.
Gastrointestinal Damage Linked to Worse Prognosis in Patients With Systemic Lupus Erythematosus
Researchers described the gastrointestinal manifestations of systemic erythematosus lupus and determined its association with disease activity, damage accrual, and prognosis.
Physical Activity, Sleep Profiles Vary in Adults With Arthritis
Four distinct physical activity profiles are detectable using activity monitoring among adults with arthritis.
Hydroxychloroquine May Not Be Associated With Preventive Effect Against SARS-CoV-2 Infection in Rheumatic Diseases
Researchers investigated the risk for SARS-CoV-2 infection in patients with rheumatic disease receiving vs not receiving hydroxychloroquine.
Phase 3 Trial of Janssen’s COVID-19 Vaccine to Evaluate Single Dose Regimen
A phase 3 trial evaluating the vaccine candidate, JNJ-78436735 (Ad26.COV2.S; Janssen), for the prevention of COVID-19 has been initiated.
Hydroxychloroquine Tied to Heart Problems Prior to Pandemic
Real-world, pre-COVID-19 adverse events data show hydroxychloroquine and chloroquine are associated with cardiovascular adverse events.
Treatment With Hydroxychloroquine Plus Azithromycin Linked to Cardiovascular Mortality in Rheumatoid Arthritis
Researchers assessed the safety of hydroxychloroquine alone and in combination with azithromycin to determine the risk associated with its use in routine care in rheumatoid arthritis.
Pulmonary Arterial Compliance May Predict Mortality in SLE-Associated PAH
Pulmonary arterial compliance was found to be strongly associated with all-cause mortality and clinical worsening in patients with systemic lupus erythematosus-associated pulmonary arterial hypertension.
Self-Reported Frailty Prevalent Among Patients With Rheumatic Musculoskeletal Diseases
Researchers described the prevalence of self-reported frailty among patients with rheumatic musculoskeletal diseases and its associated factors.
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