Researchers explored the effect of disease activity on specific health-related quality of life over time in patients with systemic lupus erythematosus, using the item response theory longitudinal model.
Researchers prospectively compared the clinical utility of diagnostic immunology testing with multianalyte assay panel testing in the diagnosis and treatment of systemic lupus erythematosus.
Researchers estimated the incidence of cancer in patients with systemic lupus erythematosus differentiating between hormone-sensitive and nonhormone sensitive cancers.
Researchers assessed the attainability and effect of the Definitions of Remission in Systemic Lupus Erythematosus (SLE) compared with the lupus low disease activity state in patients with SLE.
Researchers validated the 2017 weighted, 1997 ACR, and 2012 SLICC criteria and compared their sensitivities and specificities in patients with pediatric systemic lupus erythematosus.
Although the first phase 3 trial of anifrolumab did not meet its primary end point, other study end points that were met suggested a clinical benefit for the monoclonal antibody in systemic lupus erythematosus.
Researchers compared the rate of opioid overdose-related hospitalizations among patients with systemic lupus erythematosus and rheumatoid arthritis vs the general population.
Researchers examined the association of blood levels of hydroxychloroquine with thrombotic events in a longitudinal systemic lupus erythematous cohort.
The FDA has granted Breakthrough Therapy designation to obinutuzumab (Genentech), a CD20-directed cytolytic antibody, for the treatment of adults with lupus nephritis.
Researchers analyzed the clinical features and outcomes of infections in the central nervous system (CNS) in patients with systemic lupus erythematosus (SLE) and created a simplified scoring system to differentiate CNS infections from neuropsychiatric SLE.
This study reports the long-term renal outcomes of kidney biopsies performed at prespecified intervals to determine the safety and accuracy of tapering of maintenance immunosuppression.
New 2019 classification criteria for systemic lupus erythematosus was jointly developed by the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
