Decrease in Mortality for Patients With Autoantibody-Associated Vasculitides
From 1999 to 2017, there was a decrease in mortality among individuals with antineutrophil cytoplasmic autoantibody-associated vasculitides in the United States.
Vasculitis
VASCULITIS
Rituximab Gains Expanded Approval in Pediatrics
Granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are rare diseases that are generally specific to the lungs, kidneys and upper airways.
Diagnostic Delay Not Associated With Visual Symptoms in Giant Cell Arteritis
The study compared general and giant cell arteritis-specific characteristics in patients with and without visual symptoms, and examined the role of diagnostic delay in patients with giant cell arteritis experiencing current visual symptoms.
Apremilast Approved for Oral Ulcers Associated With Behçet Disease
The FDA has approved Otezla (apremilast; Celgene) for the treatment of adult patients with oral ulcers associated with Behçet’s disease.
Novel Risk Factors for Thromboembolism in ANCA-Associated Vasculitis
Researchers conducted a study to examine the frequency of VTEs in ANCA-associated vasculitis, and to identify its novel risk factors.
Oral Glucocorticoid-Related Infection Incidence in Giant Cell Arteritis
The incidence of infection increases with glucocorticoid dose for patients with polymyalgia rheumatica or giant cell arteritis.
Priority Review Granted to Rituximab for Pediatric Microscopic Polyangiitis
The FDA has accepted for Priority Review the supplemental BLA for Rituxan for use in combination with glucocorticoids for the treatment of granulomatosis with polyangiitis and microscopic polyangiitis in children ≥2 years old.
Orbital Mass Presentation and Management Examined in ANCA-Associated Vasculitides
Researchers described the presentation, therapeutic management, and outcomes of ANCA-associated vasculitides-related orbital mass.
Patient-Reported Outcome Measurement Information System Validated in Systemic Vasculitis
Researchers assessed the feasibility and construct validity of using PROMIS instruments in systemic vasculitis.
Effects of Clinicopathologic Classification in ANCA-Associated Vasculitis
Researchers assessed the effect of AAV reclassification based on clinicopathologic criteria and ANCA specificity.
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