Year in Review Lupus

Identifying Musculoskeletal Manifestations in Systemic Lupus Erythematosus

Investigators sought to define the clinical association of clinical and imaging definitions of synovitis in patients with SLE with musculoskeletal symptoms.

Ustekinumab Effective in Phase 2 Study for Systemic Lupus Erythematosus

Results from a phase 2 study suggest that ustekinumab might be an effective therapy in systemic lupus erythematosus.

Improving Medication Adherence With Drug Monitoring in SLE

Therapeutic drug monitoring may be useful to help clinicians assess nonadherence in patients with SLE.

Patient-Reported Outcomes Predict Mortality in Systemic Lupus Erythematosus

Patient-reported outcomes are independent predictors of mortality in systemic lupus erythematosus.

Improving Rates of Combination Pneumococcal Vaccination in Patients With SLE

Vaccination rates in patients with systemic lupus erythematosus improved significantly after the implementation of a multifaceted intervention at a rheumatology practice.

Active SLE Disease Activity, Damage Linked to Greater Mortality

The use of validated disease activity and damage metrics is important in the assessment of SLE.

Prolonged Antimalarial Exposure Increases Risk for Elevated Cardiac Biomarkers in SLE

Prolonged antimalarial therapy and persistent creatine phosphokinase elevation resulted in an increased risk for abnormal brain natriuretic peptide and cardiac troponin.

Are Adverse Pregnancy Outcomes Associated With Accelerated Cardiovascular Events in SLE?

The risk factors for accelerated cardiovascular disease among young women with SLE remain unclear, with multiple studies producing conflicting results.

High Rate of Subclinical Myocardial Injury in Systemic Lupus Erythematosus

Patients with systemic lupus erythematosus have a high prevalence of subclinical myocardial injury, as evidenced by raised high-sensitive troponin levels.

Characteristics of Early-Onset SLE Distinguished From Mimicking Conditions

Patients with early SLE had higher rates of unexplained fever than those with SLE-mimicking conditions.