Juvenile Idiopathic Arthritis
Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.
The goal of consensus treatment plans is to drive a cycle of innovation and replacement that allows the addition of new treatments and the removal of unused or ineffective strategies.
Autoantibodies that recognize cytosolic 5′-nucleotidase 1A were detected in about 25% of patients with juvenile myositis and juvenile idiopathic arthritis.
Treatment response was most significant in patients taking either tocilizumab or an interleukin-1 inhibitor.
Adalimumab was well tolerated and associated with persistent uveitis improvement in most cases.
An increase in disease activity 6 weeks postpartum suggests the need for tight follow-up of women with juvenile idiopathic arthritis.
Chronic inflammatory rheumatologic diseases benefit from early anti-inflammatory treatment; however, interdisciplinary approaches may be necessary for identifying and managing noninflammatory joint pain.
The objective of this study is to determine whether the JADAS or cJADAS would accurately predict patients with JIA in need of treatment escalation to anti-TNF after starting MTX.
Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.
Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.
Technological advances may assist children and adolescents with JIA, who are both more forgetful and more resistant to therapy.
Golimumab use in children with active polyarticular-course JIA resulted in rapid, clinically meaningful improvements.
Ongoing inflammation related to JIA may put first-time mothers at risk for complications.
These guidelines address the use of antirheumatic drugs for adults with RA, SpA, JIA, and SLE undergoing THA or TKA.
When combined with ultrasound examination, ANG-2 can help lead to the appropriate therapy for JIA.
Clinicians should consider the risk/benefit of prescribing TNFIs to children with idiopathic arthritis.
In children with active juvenile idiopathic arthritis, the treatment combination controls eye inflammation.
Tocilizumab therapy showed rapid improvement in ocular parameters for uveitis in juvenile idiopathic arthritis patients.
Juvenile idiopathic arthritis highlights this week's edition, plus other news in the world of rheumatic disease.
Study examines children with juvenile idiopathic arthritis who underwent overnight polysomnography and neurobehavioral assessments.
Panel advises that up to 50% of young patients with juvenile-onset rheumatic diseases fail to successfully transition to adult rheumatology services.
The process of transition from pediatric to adult rheumatology care represents a vulnerable period. The patient, physicians, and the patient's family must collaborate in advance planning and preparation to ensure a smooth transfer of care.
Most commonly used to treat chronic uveitis, weekly adalimumab was linked to a positive clinical response in 93% of patients.
Researchers have noted a prescribing shift towards the use of alternative biologics that they believe is mostly driven by disease subtype and history of chronic anterior uveitis.
While no association was found between previously reported risk factors of JIA, including exposure to smoking, infection early in life, or lack of breastfeeding, an association was found between JIA and premature birth.
Bristol-Myers Squibb announced the launch of Orencia (abatacept) ClickJect Autoinjector, a new autoinjector that features push button operation and step-by-step instructions to assist in the injection process.
An increase in transthyretin (TTR) autoantibodies was found in the JIA population as compared with controls.
This study investigated antibody responses to oral pathogens and the clinical features of periodontitis in children with CCP-positive juvenile idiopathic arthritis (JIA). The results of this study supported the hypothesis that P gingivalis may play a role in the pathogenesis of CCP-positive JIA.
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