Juvenile Idiopathic Arthritis
Original vs Expanded Disease Activity Scoring System in JIA Examined
October 02, 2018For a more precise assessment of disease activity and treatment effectiveness in individuals with JIA, inclusion of MCP joints should be considered in the scoring system.
Actemra SC Approved to Treat Active Systemic JIA
September 14, 2018The FDA has approved Actemra SC for the treatment of active systemic JIA alone or in combination with methotrexate in patients ≥2 years old.
Examining Gaps in Mental Health Care Among Youth With Juvenile Rheumatic Disease
August 15, 2018There is an unmet need for mental health interventions that address illness-related issues affecting youth with rheumatologic conditions.
Clinical Assessment of Juvenile Idiopathic Arthritis: Predicting Unfavorable Long-Term Outcomes
June 11, 2018Prediction models of outcomes in juvenile idiopathic arthritis have acceptable precision and require only readily available baseline variables.
Clinical Correlates of JIA Relapse After Biologic Therapy Discontinuation
May 16, 2018The investigators sought to evaluate the time patients were in remission after discontinuing biologic therapy for the treatment of JIA.
Actemra SC Approved to Treat Polyarticular Juvenile Idiopathic Arthritis
May 14, 2018The FDA has approved the subcutaneous formulation of Actemra for the treatment of active polyarticular juvenile idiopathic arthritis.
Depressive Symptoms Predict Future Pain, Disability in Adolescent JIA
May 11, 2018Baseline depressive symptoms were associated with pain and disability in adolescents with juvenile idiopathic arthritis.
Efficacy, Safety of Adalimumab vs Infliximab in JIA-Associated Uveitis
May 08, 2018Researchers evaluated the safety and efficacy of adalimumab and infliximab in the treatment of juvenile idiopathic arthritis-associated uveitis in patients treated for at least 2 years.
Treatment Targets in JIA: Comparing Definitions of Clinically Inactive Disease
April 30, 2018Investigators aimed to examine the use of treatment targets in juvenile idiopathic arthritis in terms of joint limitations, functional ability, psychosocial health, and pain levels.
Managing Uveitis in Juvenile Idiopathic Arthritis: Consensus-Based Recommendations
April 23, 2018The SHARE initiative has provided recommendations for the diagnosis and treatment of juvenile idiopathic arthritis-associated uveitis.
Clinical Features Identified in Enthesitis-Related Juvenile Idiopathic Arthritis, Juvenile Spondyloarthritis
April 20, 2018Results confirm that juvenile spondyloarthritis is characterized by its peripheral pattern at disease onset, with peripheral arthritis and enthesitis.
Genetic Risk Loci Found Within Disease Phenotypes Including SLE, JIA
April 17, 2018The Epstein-Barr virus EBNA2 protein and many coclustering human transcription factors occupied nearly half of SLE risk loci.
Ultrasound Not Predictive of Disease Flares for Inactive Juvenile Idiopathic Arthritis
April 17, 2018Abnormal ultrasound findings were common in patients with juvenile idiopathic arthritis with clinically inactive disease.
Flare Risk Examined in Juvenile Idiopathic Arthritis After Anti-TNF Therapy Discontinuation
April 11, 2018Researchers sought to determine the predictors of disease flare after anti-TNF therapy discontinuation in children with polyarticular forms of juvenile idiopathic arthritis with sustained clinically inactive disease.
Examining the Role of Neutrophils in Systemic-Onset Juvenile Idiopathic Arthritis
March 05, 2018High neutrophil counts decreased after initiation of recombinant interleukin-1 receptor agonist therapy in systemic-onset juvenile idiopathic arthritis.
TNF Inhibitor Therapy Unlikely to Affect Malignancy Risk in Children
February 26, 2018Children with juvenile idiopathic arthritis, pediatric inflammatory bowel disease, and pediatric plaque psoriasis had an increased incidence of childhood malignancies, regardless of TNFi exposure.
Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse
February 15, 2018Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.
Improving Pediatric Rheumatic Disease Care With Consensus-Based Treatment Plans
February 08, 2018The goal of consensus treatment plans is to drive a cycle of innovation and replacement that allows the addition of new treatments and the removal of unused or ineffective strategies.
More Severe Disease Found in Juvenile Myositis With Anti-NT5C1A Autoantibodies
February 07, 2018Autoantibodies that recognize cytosolic 5′-nucleotidase 1A were detected in about 25% of patients with juvenile myositis and juvenile idiopathic arthritis.
Choosing a Biologic Therapy for JIA: Etanercept vs Tocilizumab vs IL-1 Inhibitors
January 31, 2018Treatment response was most significant in patients taking either tocilizumab or an interleukin-1 inhibitor.
Adalimumab Effective in JIA-Associated Uveitis Unresponsive to Methotrexate
January 29, 2018Adalimumab was well tolerated and associated with persistent uveitis improvement in most cases.
Juvenile Idiopathic Arthritis Disease Activity Low but Stable During Pregnancy
January 12, 2018An increase in disease activity 6 weeks postpartum suggests the need for tight follow-up of women with juvenile idiopathic arthritis.
Fluorescence Optical Imaging for Diagnosis of Pediatric Rheumatologic Conditions
November 30, 2017Chronic inflammatory rheumatologic diseases benefit from early anti-inflammatory treatment; however, interdisciplinary approaches may be necessary for identifying and managing noninflammatory joint pain.
Clinical Juvenile Arthritis Disease Activity Score Use in Treat-to-Target Therapy
November 29, 2017The objective of this study is to determine whether the JADAS or cJADAS would accurately predict patients with JIA in need of treatment escalation to anti-TNF after starting MTX.
Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis
November 07, 2017Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.
Pregnancy Outcomes in SLE vs Other Connective Tissue, Inflammatory Rheumatic Conditions
November 05, 2017Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.
Evolving Technologic Strategies for Managing Juvenile Idiopathic Arthritis
September 13, 2017Technological advances may assist children and adolescents with JIA, who are both more forgetful and more resistant to therapy.
Juvenile Idiopathic Arthritis Subcutaneous Golimumab in Active Polyarticular-Course
August 24, 2017Golimumab use in children with active polyarticular-course JIA resulted in rapid, clinically meaningful improvements.
Juvenile Idiopathic Arthritis Increases Risk of Postpartum Complications
June 26, 2017Ongoing inflammation related to JIA may put first-time mothers at risk for complications.
Guidelines for Peri-Op Care in Rheumatic Disease
June 22, 2017These guidelines address the use of antirheumatic drugs for adults with RA, SpA, JIA, and SLE undergoing THA or TKA.
Rheumatology Advisor Articles
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- Ultrasound Can Reveal Renal Medulla Urate Deposits in Tophaceous Gout
- TNF-α Inhibitor Therapy May Benefit Extracellular Matrix Remodeling in Women With RA
- Examining Referral Patterns for DECT in Diagnosis, Management of Gout
- Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis
- MicroRNAs Linked to Increased Cortical Bone Porosity in Postmenopausal Women With History of Fracture
- Giant Cell Arteritis: Examining Challenges in Diagnosis and Treatment
- Manufacturers Increase Drug Prices Twice as Fast During Drug Shortages
- Identifying Warning Signs of Depression in a Fellow Clinician