Juvenile Idiopathic Arthritis
Clinical Correlates of JIA Relapse After Biologic Therapy Discontinuation
May 16, 2018The investigators sought to evaluate the time patients were in remission after discontinuing biologic therapy for the treatment of JIA.
Actemra SC Approved to Treat Polyarticular Juvenile Idiopathic Arthritis
May 14, 2018The FDA has approved the subcutaneous formulation of Actemra for the treatment of active polyarticular juvenile idiopathic arthritis.
Depressive Symptoms Predict Future Pain, Disability in Adolescent JIA
May 11, 2018Baseline depressive symptoms were associated with pain and disability in adolescents with juvenile idiopathic arthritis.
Efficacy, Safety of Adalimumab vs Infliximab in JIA-Associated Uveitis
May 08, 2018Researchers evaluated the safety and efficacy of adalimumab and infliximab in the treatment of juvenile idiopathic arthritis-associated uveitis in patients treated for at least 2 years.
Treatment Targets in JIA: Comparing Definitions of Clinically Inactive Disease
April 30, 2018Investigators aimed to examine the use of treatment targets in juvenile idiopathic arthritis in terms of joint limitations, functional ability, psychosocial health, and pain levels.
Managing Uveitis in Juvenile Idiopathic Arthritis: Consensus-Based Recommendations
April 23, 2018The SHARE initiative has provided recommendations for the diagnosis and treatment of juvenile idiopathic arthritis-associated uveitis.
Clinical Features Identified in Enthesitis-Related Juvenile Idiopathic Arthritis, Juvenile Spondyloarthritis
April 20, 2018Results confirm that juvenile spondyloarthritis is characterized by its peripheral pattern at disease onset, with peripheral arthritis and enthesitis.
Genetic Risk Loci Found Within Disease Phenotypes Including SLE, JIA
April 17, 2018The Epstein-Barr virus EBNA2 protein and many coclustering human transcription factors occupied nearly half of SLE risk loci.
Ultrasound Not Predictive of Disease Flares for Inactive Juvenile Idiopathic Arthritis
April 17, 2018Abnormal ultrasound findings were common in patients with juvenile idiopathic arthritis with clinically inactive disease.
Flare Risk Examined in Juvenile Idiopathic Arthritis After Anti-TNF Therapy Discontinuation
April 11, 2018Researchers sought to determine the predictors of disease flare after anti-TNF therapy discontinuation in children with polyarticular forms of juvenile idiopathic arthritis with sustained clinically inactive disease.
Examining the Role of Neutrophils in Systemic-Onset Juvenile Idiopathic Arthritis
March 05, 2018High neutrophil counts decreased after initiation of recombinant interleukin-1 receptor agonist therapy in systemic-onset juvenile idiopathic arthritis.
TNF Inhibitor Therapy Unlikely to Affect Malignancy Risk in Children
February 26, 2018Children with juvenile idiopathic arthritis, pediatric inflammatory bowel disease, and pediatric plaque psoriasis had an increased incidence of childhood malignancies, regardless of TNFi exposure.
Juvenile Idiopathic Arthritis: Baseline Ultrasound Abnormalities May Predict Relapse
February 15, 2018Abnormality on an ultrasound examination significantly increased the risk for flare in patients with juvenile idiopathic arthritis.
Improving Pediatric Rheumatic Disease Care With Consensus-Based Treatment Plans
February 08, 2018The goal of consensus treatment plans is to drive a cycle of innovation and replacement that allows the addition of new treatments and the removal of unused or ineffective strategies.
More Severe Disease Found in Juvenile Myositis With Anti-NT5C1A Autoantibodies
February 07, 2018Autoantibodies that recognize cytosolic 5′-nucleotidase 1A were detected in about 25% of patients with juvenile myositis and juvenile idiopathic arthritis.
Choosing a Biologic Therapy for JIA: Etanercept vs Tocilizumab vs IL-1 Inhibitors
January 31, 2018Treatment response was most significant in patients taking either tocilizumab or an interleukin-1 inhibitor.
Adalimumab Effective in JIA-Associated Uveitis Unresponsive to Methotrexate
January 29, 2018Adalimumab was well tolerated and associated with persistent uveitis improvement in most cases.
Juvenile Idiopathic Arthritis Disease Activity Low but Stable During Pregnancy
January 12, 2018An increase in disease activity 6 weeks postpartum suggests the need for tight follow-up of women with juvenile idiopathic arthritis.
Fluorescence Optical Imaging for Diagnosis of Pediatric Rheumatologic Conditions
November 30, 2017Chronic inflammatory rheumatologic diseases benefit from early anti-inflammatory treatment; however, interdisciplinary approaches may be necessary for identifying and managing noninflammatory joint pain.
Clinical Juvenile Arthritis Disease Activity Score Use in Treat-to-Target Therapy
November 29, 2017The objective of this study is to determine whether the JADAS or cJADAS would accurately predict patients with JIA in need of treatment escalation to anti-TNF after starting MTX.
Internet Intervention Improves Pain, QoL in Juvenile Idiopathic Arthritis
November 07, 2017Psychoeducational treatments can aid in the transition to adult care, but this is often lacking for teens due to access issues.
Pregnancy Outcomes in SLE vs Other Connective Tissue, Inflammatory Rheumatic Conditions
November 05, 2017Real-world data indicate that although most patients with systemic lupus erythematosus or connective tissue diseases have successful pregnancies, more adverse pregnancy outcomes occur.
Evolving Technologic Strategies for Managing Juvenile Idiopathic Arthritis
September 13, 2017Technological advances may assist children and adolescents with JIA, who are both more forgetful and more resistant to therapy.
Juvenile Idiopathic Arthritis Subcutaneous Golimumab in Active Polyarticular-Course
August 24, 2017Golimumab use in children with active polyarticular-course JIA resulted in rapid, clinically meaningful improvements.
Juvenile Idiopathic Arthritis Increases Risk of Postpartum Complications
June 26, 2017Ongoing inflammation related to JIA may put first-time mothers at risk for complications.
Guidelines for Peri-Op Care in Rheumatic Disease
June 22, 2017These guidelines address the use of antirheumatic drugs for adults with RA, SpA, JIA, and SLE undergoing THA or TKA.
ANG-2 as Disease Marker in Children With Juvenile Idiopathic Arthritis
June 15, 2017When combined with ultrasound examination, ANG-2 can help lead to the appropriate therapy for JIA.
Juvenile Idiopathic Arthritis Treatment With TNFIs Linked to Infection Risk
June 02, 2017Clinicians should consider the risk/benefit of prescribing TNFIs to children with idiopathic arthritis.
MTX + Adalimumab Effective in JIA-Associated Uveitis
May 04, 2017In children with active juvenile idiopathic arthritis, the treatment combination controls eye inflammation.
Tocilizumab Highly Effective in Refractory Juvenile Idiopathic Arthritis-associated Uveitis
March 21, 2017Tocilizumab therapy showed rapid improvement in ocular parameters for uveitis in juvenile idiopathic arthritis patients.
Rheumatology Advisor Articles
- Alternative Measurement of Psoriasis Severity Effective in CZP-Treated Psoriatic Arthritis
- Incident Gout Risk, Serum Urate, and Comorbidities: What Are the Links?
- Addressing Psychiatric Comorbidities in Inflammatory Rheumatic Diseases
- Clinician Roundtable: Improving Quality of Life in Systemic Lupus Erythematosus
- Incidence of Clinically Significant GI Events in NSAID-Treated Arthritis
- EULAR Releases Recommendations for Pain Management in OA, Inflammatory Arthritis
- Risk of Developing Herpes Zoster Increased in Rheumatoid Arthritis
- Supervised, Intense Exercise Improves Physical Fitness in Older Adults With RA
- Risks Associated With Co-Administration of Aspirin and Other NSAIDs
- The Dorsal 4-Finger Technique: A New Method to Examine Joints in Rheumatoid Arthritis
- Gout, Urate-Lowering Therapy Not Associated With Risk for Fragility Fracture
- Does Exposure to Passive Smoke Increase Rheumatoid Arthritis Risk?
- Pegloticase Retreatment Effective for Gout After Gap in Therapy
- Tofacitinib Reduces MRI Inflammation, May Improve Outcomes in Ankylosing Spondylitis
- Associations Between Site-Specific BMD, Anthropometric, Glucose Homeostasis Traits