Osteoarthritis News Archive

One-Session Intervention for Hand OA Improved Grip Strength, Patient Satisfaction

One-Session Intervention for Hand OA Improved Grip Strength, Patient Satisfaction

Investigators examined the effect of an interdisciplinary, combined intervention in patients with hand osteoarthritis.

Joint Mobilization Plus Exercise Beneficial for Knee Osteoarthritis

Joint Mobilization Plus Exercise Beneficial for Knee Osteoarthritis

Patellar mobilization therapy plus exercise has the potential to reduce pain and improve function and quality of life for patients with knee OA.

Higher Fibrosis Scores Associated With Lower Radiographic Severity in Knee OA

Higher Fibrosis Scores Associated With Lower Radiographic Severity in Knee OA

Higher fibrosis scores were associated with lower radiographic disease severity over time in patients with knee osteoarthritis.

FDA Fast Track Designation Granted for Investigational Osteoarthritis Treatment

FDA Fast Track Designation Granted for Investigational Osteoarthritis Treatment

The FDA has granted Fast Track designation for GLPG1972/S201086 for the treatment of osteoarthritis.

Four Pain Susceptibility Phenotypes Identified in Knee Osteoarthritis

Four Pain Susceptibility Phenotypes Identified in Knee Osteoarthritis

Four pain susceptibility phenotypes were identified in patients who had or were at risk for knee osteoarthritis, as well as risk factors for the development of persistent knee pain.

Moderate Physical Activity Slows Cartilage Loss in Women With Knee Osteoarthritis

Moderate Physical Activity Slows Cartilage Loss in Women With Knee Osteoarthritis

Researchers examined the effect of physical activity on cartilage thickness loss in knee osteoarthritis.

Physician-Patient Discordance of Global Assessment Higher in Osteoarthritis vs Rheumatoid Arthritis

Physician-Patient Discordance of Global Assessment Higher in Osteoarthritis vs Rheumatoid Arthritis

Researchers compared patient-physician discordance in global assessment in patients with osteoarthritis vs patients with rheumatoid arthritis seen in routine care.

No Benefit Found for Low-Dose Radiation Therapy for in Treatment of Knee Osteoarthritis

No Benefit Found for Low-Dose Radiation Therapy for in Treatment of Knee Osteoarthritis

Data show that low-dose radiation therapy does not lead to a substantial reduction in symptoms in patients with knee OA compared with sham therapy.

CDC: About 1 in 3 Adults With Prediabetes Has Arthritis

CDC: About 1 in 3 Adults With Prediabetes Has Arthritis

About 1 in 3 adults with prediabetes has arthritis, and half of those with both conditions are physically inactive and/or obese.

Effects of Exercise Therapy on Molecular Biomarkers in Knee Osteoarthritis

Effects of Exercise Therapy on Molecular Biomarkers in Knee Osteoarthritis

Exercise therapy does not increase the concentration of molecular biomarkers related to cartilage turnover and inflammation.

Prediction Models Developed to Predict Risk for Total Hip, Knee Replacements

Prediction Models Developed to Predict Risk for Total Hip, Knee Replacements

Researchers developed two models to estimate an individual's risk for primary THR and TKR.

Childhood Maltreatment Associated With Arthritis in Adulthood

Childhood Maltreatment Associated With Arthritis in Adulthood

Childhood maltreatment was associated with adulthood arthritis, particularly among those who experienced severe or frequent abuse.

Assessing Measurement Properties of Self-Report Physical Activity Instruments for Osteoarthritis

Assessing Measurement Properties of Self-Report Physical Activity Instruments for Osteoarthritis

Researchers evaluated measurement properties of self-report physical activity instruments for patients with osteoarthritis.

High Bone Mineral Density Predicts Progression of Knee, Hip Osteoarthritis

High Bone Mineral Density Predicts Progression of Knee, Hip Osteoarthritis

Researchers examined the longitudinal relationship between bone mineral density and the incidence and progression of knee, hip, and hand osteoarthritis.

Local Gentamicin Application Ineffective in Treatment of Periprosthetic Joint Infection

Local Gentamicin Application Ineffective in Treatment of Periprosthetic Joint Infection

The use of gentamicin-impregnated beads and/or sponges should be discouraged in early acute periprosthetic joint infection as their use is associated with high failure rates.

Aspirin, Anticoagulants Similarly Prevent VTE After TKA

Aspirin, Anticoagulants Similarly Prevent VTE After TKA

Among patients undergoing TKA, aspirin alone may provide protection against postoperative VTE that is similar to that of other anticoagulants.

Prevalence of RA-Associated Autoantibodies Not Associated With Erosive Hand Osteoarthritis

Prevalence of RA-Associated Autoantibodies Not Associated With Erosive Hand Osteoarthritis

The presence of 3 common rheumatoid arthritis-associated antibodies were not associated with erosive disease in patients with hand osteoarthritis.

Walking Each Day May Cut Risk for TKA Over 5 Years

Walking Each Day May Cut Risk for TKA Over 5 Years

For individuals with knee OA, replacing time not walking with walking at moderate-to-vigorous intensity is associated with reduced risk for TKA over 5 years.

Differentiation of Knee Pain Phenotypes Among Older Adults

Differentiation of Knee Pain Phenotypes Among Older Adults

A population-based, cohort study was conducted to identify knee pain in a group of older adults.

Knee Effusion Volume Predicts Osteoarthritis Progression and Knee Replacement

Knee Effusion Volume Predicts Osteoarthritis Progression and Knee Replacement

Investigators sought to determine if change in knee effusion volume from baseline to 1 year was predictive of cartilage volume loss and osteoarthritis progression in individuals at risk for osteoarthritis of the knee.

Clinical Comorbidities Up After Arthroscopic Hip Surgery

Clinical Comorbidities Up After Arthroscopic Hip Surgery

Following elective arthroscopic hip surgery, the rate of 7 major clinical comorbidities increases significantly.

Triamcinolone Acetonide Extended-Release Effective for Knee OA in Patients With Type 2 Diabetes

Triamcinolone Acetonide Extended-Release Effective for Knee OA in Patients With Type 2 Diabetes

Intra-articular injection of triamcinolone acetonide extended-release may be an effective corticosteroid treatment in patients with knee osteoarthritis and comorbid type 2 diabetes.

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

Pain Severity May Partly Mediate the Association Between Depression and Physical Performance in Knee OA

Pain may partly mediate the observed association between physical performance and depressive symptoms in patients with radiographic knee osteoarthritis.

Exploring the Association Between Quadriceps Strength, Functional Outcomes in Knee Osteoarthritis

Exploring the Association Between Quadriceps Strength, Functional Outcomes in Knee Osteoarthritis

Researchers assessed quadriceps strength and physical function in individuals with knee osteoarthritis.

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

Replacing Sleep, Sedentary Behavior With Physical Activity Beneficial in Knee Osteoarthritis

Replacing at least 10 minutes a day of time spent sedentary, asleep, or in light physical activity with moderate physical activity may be associated with significant reductions in bodily pain interference and knee pain in adults at risk for osteoarthritis knee pain.

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

Effects of Statin Use on Pain Outcomes in Knee Osteoarthritis

Individuals using statins over 5 years and those using atorvastatin reported a lower risk for future osteoarthritis-related knee pain.

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

Combining Hyaluronic Acid With Platelet-Rich Plasma Injections for Primary Knee Osteoarthritis

Hyaluronic acid therapy may be more effective when supplemented with intra-articular platelet-rich plasma injections vs alone in treating primary knee osteoarthritis.

Extensive Effusion-Synovitis Linked to Progression of Cartilage Damage in OA With Meniscal Tear

Extensive Effusion-Synovitis Linked to Progression of Cartilage Damage in OA With Meniscal Tear

Persistence of extensive effusion-synovitis over time was associated with the greatest risk for cartilage damage progression.

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

Effects of Pain, Depression, and Insomnia on Health Care Use in Older Adults With Osteoarthritis

The combined effects of pain with insomnia and pain with depression increased diverse types of health care use.

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

Individualized Treatment of Late Acute Prosthetic Joint Infection May Decrease Failure Rate

Treatment strategies for late acute prosthetic joint infections should be individualized according to patients' age, comorbidities, clinical presentation, and microorganism causing the infection.

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

Decreased Pain May Mediate Effects of Soft Knee Brace on Activity Limitations in Knee OA

A decrease of pain and a decrease of dynamic knee instability mediated the effect of wearing a soft knee brace on reduction of activity limitations.

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

Radiographic Changes of Osteoarthritis Associated With Persistent Knee Pain

Researchers examined the correlation between knee pain and radiographic features of osteoarthritis.

Updated Recommendations for the Management of Hand Osteoarthritis Released by EULAR

Updated Recommendations for the Management of Hand Osteoarthritis Released by EULAR

EULAR has released updated guidelines for the management of hand osteoarthritis.

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

The Relationship Between Hip/Knee Osteoarthritis and Risk for Incident Diabetes

Bilateral hip or knee osteoarthritis was significantly associated with a 16% to 25% increased risk for incident diabetes.

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

Hip Injury and "Giving Way" Associated With Pain Exacerbation in Hip Osteoarthritis

Buckling of the hip joint, also referred to as "giving way," and hip injuries may be associated with hip pain worsening in patients with symptomatic hip osteoarthritis.

Exposure to Oral Osteoarthritis Therapies Not Linked to Increased Risk for Knee Replacement

Exposure to Oral Osteoarthritis Therapies Not Linked to Increased Risk for Knee Replacement

The main risk factors leading to knee replacement surgery in patients with osteoarthritis include disease severity, symptoms, and high BMI.

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

Positive Results for Novel Osteoarthritis Pain Treatment in Phase 3 Trial

Change in pain and physical function score from baseline were chosen as the co-primary endpoints.

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

Daily and Retrospective Pain Measurements Comparable in Hip Osteoarthritis

The reliability of retrospective and daily pain measurements was comparable among patients with hip osteoarthritis, except in individuals with severe intermittent pain for whom retrospective measurements may be less reliable.

Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data

Performance Phenotypes of Lumbar Spinal Stenosis and OA With Accelerometry Data

The use of accelerometry data has led to the discovery of performance phenotypes of lumbar spinal stenosis and osteoarthritis.

Revision Rates for Arthritis-Related Hip Replacement Down

Revision Rates for Arthritis-Related Hip Replacement Down

Use of cross-linked polyethylene has significantly reduced the revision rate following total hip arthroplasty for osteoarthritis.

Knee Load Associated With Increased Walking Pain in Osteoarthritis

Knee Load Associated With Increased Walking Pain in Osteoarthritis

Researchers examine the association between the knee adduction moment and increased knee pain during walking in patients with knee osteoarthritis.

Knee Joint Hypermobility May Be Linked to OA Foot, Ankle Symptoms

Knee Joint Hypermobility May Be Linked to OA Foot, Ankle Symptoms

Researchers examine the relationship of joint hypermobility with osteoarthritis and symptoms at the foot or ankle.

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Higher PainDETECT Scores, Neuropathic Pain Preoperatively May Increase Risk for Chronic Pain Post-TKR

Individuals with knee osteoarthritis who have indicators of high vs low/no levels of neuropathic pain may be at elevated risk for chronic pain after total knee replacement surgery.

Walking Disability Associated With Arterial Stiffness in Osteoarthritis

Walking Disability Associated With Arterial Stiffness in Osteoarthritis

Six-minute walking distance was significantly associated with arterial stiffness in individuals with osteoarthritis.

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

Positive Phase 3 Results for Novel OA Pain Treatment Tanezumab

Pfizer and Lilly announced positive results from a study evaluating tanezumab, an investigational humanized monoclonal antibody, for the treatment of OA pain.

Risk for Knee Osteoarthritis in Adolescent Men Predicted in Modified Nottingham Model

Risk for Knee Osteoarthritis in Adolescent Men Predicted in Modified Nottingham Model

Diagnostic prediction modeling for knee osteoarthritis in adolescent men helps calculate the individual and population risk of developing knee osteoarthritis over 40 years.

Neuropathic Symptoms Worsen Quality of Life, Function in Hip, Knee Osteoarthritis

Neuropathic Symptoms Worsen Quality of Life, Function in Hip, Knee Osteoarthritis

Neuropathic-like symptoms may affect pain-related quality of life ratings and function in patients with hip and knee osteoarthritis, respectively.

Increased Physical Activity Improves Mobility After Joint Replacement in Older Women

Increased Physical Activity Improves Mobility After Joint Replacement in Older Women

Women with osteoarthritis who reported lower physical activity levels before total joint replacement were more likely to experience mobility limitations in late life.

Statin Initiation Not Associated With Incident Hand Osteoarthritis

Statin Initiation Not Associated With Incident Hand Osteoarthritis

Researchers observed no association between statin initiation and incident hand osteoarthritis.

Slower Walking Speed Linked to Increased BML in Accelerated Knee Osteoarthritis

Slower Walking Speed Linked to Increased BML in Accelerated Knee Osteoarthritis

Changes in the 20-meter walking test were associated with worsening in bone marrow lesions and effusion volume in adults who developed accelerated knee OA.

Preterm Birth, Low Birth Weight Associated With Hip Osteoarthritis

Preterm Birth, Low Birth Weight Associated With Hip Osteoarthritis

Preterm birth and low birth weight have been linked to hip bone shape abnormalities and hip osteoarthritis.

Greater Weight Loss Linked to Superior Outcomes in Knee OA

Greater Weight Loss Linked to Superior Outcomes in Knee OA

For overweight and obese older adults with knee osteoarthritis, greater weight loss is associated with superior clinical and mechanistic outcomes.

BMI May Sufficiently Capture Knee OA Risk Associated With Increased Localized Adiposity

BMI May Sufficiently Capture Knee OA Risk Associated With Increased Localized Adiposity

Researchers sought to determine whether central or peripheral adiposity measures are associated with incident radiographic knee osteoarthritis independent of BMI.

Hormonal, Reproductive Factors Associated With Knee Osteoarthritis in Women

Hormonal, Reproductive Factors Associated With Knee Osteoarthritis in Women

Investigators sought to determine whether female reproductive and hormonal factors affect the incidence of total knee arthroplasty for osteoarthritis.

The Reliable Change Index: A Novel Approach to Estimate Osteoarthritis Progression

The Reliable Change Index: A Novel Approach to Estimate Osteoarthritis Progression

The Reliable Change Index may be an effective method for identifying changes in joint space width in clinical and research settings.

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

PJI is a challenging complication of joint arthroplasty with few effective treatment options.

New Combination Drug Approved to Treat Hypertension and OA Pain

New Combination Drug Approved to Treat Hypertension and OA Pain

Consensi combines amlodipine besylate, a calcium-channel blocker, and celecoxib, a nonsteroidal anti-inflammatory drug.

Efficacy, Safety of OnabotulinumtoxinA Assessed for Knee OA Treatment

Efficacy, Safety of OnabotulinumtoxinA Assessed for Knee OA Treatment

Investigators sought to evaluate intra-articular onabotulinumtoxinA 400 U and 200 U in reducing symptoms of knee OA in patients with nociceptive pain.

Patient-Reported Swelling vs MRI-Defined Effusion-Synovitis in OA With Meniscal Tear

Patient-Reported Swelling vs MRI-Defined Effusion-Synovitis in OA With Meniscal Tear

Researchers sought to investigate the cross-sectional association between patient-reported swelling and effusion-synovitis on MRI in patients with OA and meniscal tear.

Late-Life Mobility Limitations Linked to Obesity After Arthroplasty for OA in Women

Late-Life Mobility Limitations Linked to Obesity After Arthroplasty for OA in Women

Baseline obesity is associated with an increased risk for late-life mobility limitations in women undergoing joint replacement for OA.

Oral Risedronate May Reduce Bone Resorption After Total Hip Arthroplasty

Oral Risedronate May Reduce Bone Resorption After Total Hip Arthroplasty

Risedronate could significantly reduce periprosthetic bone resorption in patients undergoing total hip arthroplasty.

Provider Counseling for Weight Loss Up for Arthritis, Obesity

Provider Counseling for Weight Loss Up for Arthritis, Obesity

In 2014, healthcare provider counseling for weight loss for adults with arthritis and overweight or obesity was 45.5%, which increased from 10.4% in 2002.

Zilretta Benefits "Real-World" Patients With Knee OA, Says Study

Zilretta Benefits "Real-World" Patients With Knee OA, Says Study

Interim data have been released from a phase 3b, open-label study that evaluated the safety and tolerability of repeat administration of Zilretta in patients with knee osteoarthritis.

Prevalence of Arthritis Assessed in the United States

Prevalence of Arthritis Assessed in the United States

Men, non-Hispanic blacks, and participants with low income or obesity had the most pronounced decrease in RA prevalence.

Tibiofemoral MRI May Be Predictive of Radiographic Knee OA in Overweight, Obese Women

Tibiofemoral MRI May Be Predictive of Radiographic Knee OA in Overweight, Obese Women

Researchers sought to determine the predictive value of tibiofemoral MRI, patellofemoral MRI, and KLG1 for the incidence of clinical or radiographic knee OA.

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

In patients with painful hip osteoarthritis, an intramuscular glucocorticoid injection may effectively alleviate hip pain in the short-term.

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

Intravenous and subcutaneous administration of tanezumab may provide similar analgesia and tolerability in patients with hip or knee osteoarthritis.

Bariatric Surgery Lessens Knee OA Pain More in Certain Patients

Bariatric Surgery Lessens Knee OA Pain More in Certain Patients

Laparoscopic gastric band surgery is associated with more improvement in knee osteoarthritis in younger patients and in patients without prior knee injury.

Intra-articular Knee Injection Increases Intraocular Pressure in Osteoarthritis

Intra-articular Knee Injection Increases Intraocular Pressure in Osteoarthritis

Intraocular pressure was increased in patients who underwent a triamcinolone steroid knee injection, but not in patients who received a hyaluronic acid knee injection.

Total Hip Arthroplasty Revision Rate Examined From 2007 to 2013

Total Hip Arthroplasty Revision Rate Examined From 2007 to 2013

Patients aged 45 to 64 had an increase in the total hip arthroplasty revision rate from 2007 to 2013.

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

Researchers sought to identify associations of female reproductive factors with incidence of total knee arthroplasty in osteoarthritis.

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

Opioids and nonopioid analgesics were found to provide similar improvements in pain-related function in patients with chronic back pain or knee or hip OA pain.

Geniculate Artery Embolization Reduces Pain, Disability in Knee Osteoarthritis

Geniculate Artery Embolization Reduces Pain, Disability in Knee Osteoarthritis

Reduction in pain and disability for knee OA is linked with minimally invasive, image-guided geniculate artery embolization.

Predicting Response to Intra-Articular Hyaluronic Acid Treatment in Knee Osteoarthritis

Predicting Response to Intra-Articular Hyaluronic Acid Treatment in Knee Osteoarthritis

Investigators sought to identify determinants associated with improved response to intra-articular hyaluronic acid treatment in individuals with knee OA.

Painful Temporomandibular Joint Osteoarthritis: Glucosamine Supplements vs Ibuprofen

Painful Temporomandibular Joint Osteoarthritis: Glucosamine Supplements vs Ibuprofen

The effects of glucosamine supplements were not superior to the effects of ibuprofen in the treatment of patients with temporomandibular joint OA.

Efficacy of Colchicine for the Reduction of Symptoms in Knee Osteoarthritis

Efficacy of Colchicine for the Reduction of Symptoms in Knee Osteoarthritis

Researchers sought to investigate the effectiveness of colchicine on pain and function in symptomatic knee osteoarthritis.

Costs of Stem Cell Therapy Quantified for Knee Osteoarthritis

Costs of Stem Cell Therapy Quantified for Knee Osteoarthritis

Stem cell therapy for knee osteoarthritis is expanding, with costs exceeding $5000 for each therapy.

Pain Outcomes in Knee Osteoarthritis: Total Knee Replacement vs Nonsurgical Interventions

Pain Outcomes in Knee Osteoarthritis: Total Knee Replacement vs Nonsurgical Interventions

Low pressure pain thresholds at baseline predicted worse pain outcomes after total knee replacement surgery, but did not predict outcomes after nonsurgical interventions.

Exercise Interventions in Knee Osteoarthritis: Physical Therapy vs Tai Chi

Exercise Interventions in Knee Osteoarthritis: Physical Therapy vs Tai Chi

The dose-response effects of physical therapy and tai chi for patients with knee OA are approximately linear.

Early Radiographic Knee OA to Joint Arthroplasty: Factors of Structural Progression

Early Radiographic Knee OA to Joint Arthroplasty: Factors of Structural Progression

More than half of patients with no or mild radiographic knee osteoarthritis prior to knee replacement surgery progressed to severe osteoarthritis over 4 years of follow-up.

Aspirin Similar to Rivaroxaban for VTE Prophylaxis After Hip, Knee Arthroplasty

Aspirin Similar to Rivaroxaban for VTE Prophylaxis After Hip, Knee Arthroplasty

Results from the EPCAT II trial show that aspirin was not significantly different from rivaroxaban for the prevention of deep vein thrombosis or pulmonary embolism after total hip or knee arthroplasty.

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Researcher sought to determine the effectiveness of hydroxychloroquine vs placebo as an analgesic treatment of hand osteoarthritis.

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

The effects of combination COX-2 inhibitor therapy with metformin on joint replacement rates were examined in patients with osteoarthritis and diabetes.

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

In older patients with knee OA, pain expectancy may affect the pain experience after genuine and sham electroacupuncture.

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Patients with end-stage knee or hip osteoarthritis may often experience neuropathic pain, particularly at rest.

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Use of the 2006 Orlando criteria vs the 2007 Budapest criteria for diagnosis of CRPS may lead to misdiagnosis of unexplained pain after TKA.

Knee Replacement Rates and Outcomes Vary by Race in the United States

Knee Replacement Rates and Outcomes Vary by Race in the United States

There is a need for programs that are designed to decrease disparities in joint replacement use among various populations.

Many NSAID Users Exceed Daily Dose Limit

Many NSAID Users Exceed Daily Dose Limit

Many individuals who use nonsteroidal anti-inflammatory drugs tend to exceed the daily dose limit.

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

The use of celecoxib in patients with OA and RA was associated with a similar or a lower risk for cardiovascular, gastrointestinal, and renal adverse events compared with ibuprofen and naproxen.

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

Routine rehabilitation therapy along with adjunctive acupuncture may not provide a significant benefit over exercise, after total knee replacement.

Do Genicular Nerve Blocks Predict Radiofrequency Ablation Outcomes in Osteoarthritis?

Do Genicular Nerve Blocks Predict Radiofrequency Ablation Outcomes in Osteoarthritis?

Genicular nerve block may not predict pain relief following genicular nerve cooled radiofrequency ablation in patients with chronic knee pain due to OA.

Examining Symptomatic, Radiographic Benefits of Bisphosphonate Treatment in Knee Osteoarthritis

Examining Symptomatic, Radiographic Benefits of Bisphosphonate Treatment in Knee Osteoarthritis

Seven studies were included in a meta-analysis examining the potential benefit of bisphosphonate therapy in knee osteoarthritis.

Intra-articular Betamethasone Associated With Increased Insulin Resistance in Type 2 Diabetes

Intra-articular Betamethasone Associated With Increased Insulin Resistance in Type 2 Diabetes

Insulin resistance may be experienced by patients with T2D who receive an intra-articulate corticosteroid of betamethasone injection at the knee joint.

Clinician Counseling for Exercise Increased Among Adults With Arthritis Between 2002 and 2014

Clinician Counseling for Exercise Increased Among Adults With Arthritis Between 2002 and 2014

There was an increase in the age-adjusted prevalence of reporting health care provider counseling for exercise in adults with arthritis.

Inflammation in Rheumatic Diseases May Be Associated With Increased Risk of Dementia

Inflammation in Rheumatic Diseases May Be Associated With Increased Risk of Dementia

Patients with rheumatic diseases have a higher risk for dementia.

Hyaluronic Acid Injections May Delay Total Knee Replacement in Osteoarthritis

Hyaluronic Acid Injections May Delay Total Knee Replacement in Osteoarthritis

The use of intra-articular hyaluronic acid injections in patients with osteoarthritis of the knee has shown efficacy in delaying total knee replacement surgery.

Association Between Physical Activity and Joint Symptoms Modified by BMI in Middle-Aged Women

Association Between Physical Activity and Joint Symptoms Modified by BMI in Middle-Aged Women

A study sought to determine whether physical activity has a protective effect against development of joint symptoms in middle-aged women.

Short- and Long-Acting Opioids Equally Effective for Osteoarthritis Pain Management

Short- and Long-Acting Opioids Equally Effective for Osteoarthritis Pain Management

Short-acting opioids are comparable with long-acting opioid medications for managing pain in patients with chronic osteoarthritis.

Cooled Radiofrequency Ablation Effective for Osteoarthritis Knee Pain

Cooled Radiofrequency Ablation Effective for Osteoarthritis Knee Pain

For patients with osteoarthritis-related knee pain, cooled radiofrequency ablation may provide greater pain relief compared with steroid injections.

Hydroxychloroquine vs Placebo for Patients With Osteoarthritis of the Hands

Hydroxychloroquine vs Placebo for Patients With Osteoarthritis of the Hands

Hydroxychloroquine is not significantly more effective in treating osteoarthritis of the hand than placebo.

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