Thoracic Manifestations in Connective Tissue Disease: A Review

Thoracic manifestations are common in connective tissue disease, also called collagen vascular disease.

Noninferiority of Celecoxib to Ibuprofen & Naproxen for CV Events: Understanding Implications of the PRECISION Trial

Numerically fewer Antiplatelet Trialists Collaboration composite outcome events occurred with celecoxib treatment than with naproxen and ibuprofen. PRECISION lead investigator Dr Steven Nissen discusses clinical ...

The Impact of Obesity on Arthritis Outcomes

Obesity may affect risk of developing osteoarthritis and rheumatoid arthritis, and it has been linked with increased disease activity and adverse clinical outcomes.

Review of the Evidence Behind Platelet-Rich Plasma Therapy

Platelet-rich plasma (PRP) therapy is being used by clinicians to treat patients with symptomatic or post-traumatic osteoarthritis. While basic science and preclinical data support some ...

Conservative Management Options for Osteoarthritis

Conservative treatment options include weight loss, physical therapy, activity modification, drugs, orthotics, and intra-articular injections.

Latest News

Aspirin Effective for VTE Prophylaxis After Hip, Knee Arthroplasty

Aspirin Effective for VTE Prophylaxis After Hip, Knee Arthroplasty

Results from the EPCAT II trial show that aspirin was not significantly different from rivaroxaban for the prevention of deep-vein thrombosis or pulmonary embolism after total hip or knee arthroplasty.

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Researcher sought to determine the effectiveness of hydroxychloroquine vs placebo as an analgesic treatment of hand osteoarthritis.

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

The effects of combination COX-2 inhibitor therapy with metformin on joint replacement rates were examined in patients with osteoarthritis and diabetes.

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

In older patients with knee OA, pain expectancy may affect the pain experience after genuine and sham electroacupuncture.

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Patients with end-stage knee or hip osteoarthritis may often experience neuropathic pain, particularly at rest.

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Use of the 2006 Orlando criteria vs the 2007 Budapest criteria for diagnosis of CRPS may lead to misdiagnosis of unexplained pain after TKA.

Knee Replacement Rates and Outcomes Vary by Race in the United States

Knee Replacement Rates and Outcomes Vary by Race in the United States

There is a need for programs that are designed to decrease disparities in joint replacement use among various populations.

Many NSAID Users Exceed Daily Dose Limit

Many NSAID Users Exceed Daily Dose Limit

Many individuals who use nonsteroidal anti-inflammatory drugs tend to exceed the daily dose limit.

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

The use of celecoxib in patients with OA and RA was associated with a similar or a lower risk for cardiovascular, gastrointestinal, and renal adverse events compared with ibuprofen and naproxen.

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

Routine rehabilitation therapy along with adjunctive acupuncture may not provide a significant benefit over exercise, after total knee replacement.