Examining Unmet Needs of Joint Disease Associated With Calcium Pyrophosphate Crystal Deposition

Addressing the challenges associated with clinical management of calcium pyrophosphate crystal deposition must start with understanding the unmet needs of associated joint damage and establishing ...

Radiofrequency Ablation for Chronic Hip Pain in Osteoarthritis: Reviewing the Evidence

The available evidence suggests that radiofrequency ablation is a feasible treatment option for chronic hip pain associated with degenerative diseases.

Managing Dietary Supplements and Complementary Medicines in Osteoarthritis

Dietary supplements are widely used by patients with osteoarthritis, but the safety and efficacy of supplements remain unclear and are often misconstrued by mainstream media.

Thoracic Manifestations in Connective Tissue Disease: A Review

Thoracic manifestations are common in connective tissue disease, also called collagen vascular disease.

Noninferiority of Celecoxib to Ibuprofen & Naproxen for CV Events: Understanding Implications of the PRECISION Trial

Numerically fewer Antiplatelet Trialists Collaboration composite outcome events occurred with celecoxib treatment than with naproxen and ibuprofen. PRECISION lead investigator Dr Steven Nissen discusses clinical ...

The Impact of Obesity on Arthritis Outcomes

Obesity may affect risk of developing osteoarthritis and rheumatoid arthritis, and it has been linked with increased disease activity and adverse clinical outcomes.

Review of the Evidence Behind Platelet-Rich Plasma Therapy

Platelet-rich plasma (PRP) therapy is being used by clinicians to treat patients with symptomatic or post-traumatic osteoarthritis. While basic science and preclinical data support some ...

Conservative Management Options for Osteoarthritis

Conservative treatment options include weight loss, physical therapy, activity modification, drugs, orthotics, and intra-articular injections.

Latest News

Sprifermin Improved Cartilage Morphology, Thickness in Knee Osteoarthritis

Sprifermin Improved Cartilage Morphology, Thickness in Knee Osteoarthritis

Sprifermin has a positive effect on cartilage morphology and cartilage thickness in radiographic knee osteoarthritis.

Depressive Symptom Onset Linked to Disease Severity in Knee OA

Depressive Symptom Onset Linked to Disease Severity in Knee OA

To effectively treat individuals with radiographic knee OA and comorbid depressive disorder, it is necessary to use a combined treatment strategy of 2 interventions delivered in parallel to simultaneously target each condition.

RA Associated With Greater Reduction in Short-Term Disease Burden vs Osteoarthritis

RA Associated With Greater Reduction in Short-Term Disease Burden vs Osteoarthritis

Investigators analyzed MDHAQ/RAPID3 scores in patients with osteoarthritis or rheumatoid arthritis to assess disease burden associated with each rheumatic disease.

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

Zoledronic Acid May Not Improve Knee Osteoarthritis-Related Pain, Function Long-Term

Zoledronic acid did not significantly reduce knee pain or bone marrow lesion size overall in patients with knee osteoarthritis over 24 months.

NSAID Use Mediates CVD Risk in Osteoarthritis

NSAID Use Mediates CVD Risk in Osteoarthritis

Nonsteroidal anti-inflammatory drug use mediated a substantial amount of cardiovascular disease risk in osteoarthritis.

BMI May Sufficiently Capture Knee OA Risk Associated With Increased Localized Adiposity

BMI May Sufficiently Capture Knee OA Risk Associated With Increased Localized Adiposity

Researchers sought to determine whether central or peripheral adiposity measures are associated with incident radiographic knee osteoarthritis independent of BMI.

Hormonal, Reproductive Factors Associated With Knee Osteoarthritis in Women

Hormonal, Reproductive Factors Associated With Knee Osteoarthritis in Women

Investigators sought to determine whether female reproductive and hormonal factors affect the incidence of total knee arthroplasty for osteoarthritis.

The Reliable Change Index: A Novel Approach to Estimate Osteoarthritis Progression

The Reliable Change Index: A Novel Approach to Estimate Osteoarthritis Progression

The Reliable Change Index may be an effective method for identifying changes in joint space width in clinical and research settings.

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

Treatment for Prosthetic Joint Infections Gets FDA's QIDP Designation

PJI is a challenging complication of joint arthroplasty with few effective treatment options.

New Combination Drug Approved to Treat Hypertension and OA Pain

New Combination Drug Approved to Treat Hypertension and OA Pain

Consensi combines amlodipine besylate, a calcium-channel blocker, and celecoxib, a nonsteroidal anti-inflammatory drug.