Osteoarthritis

Aspirin Effective for VTE Prophylaxis After Hip, Knee Arthroplasty

Aspirin Effective for VTE Prophylaxis After Hip, Knee Arthroplasty

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Results from the EPCAT II trial show that aspirin was not significantly different from rivaroxaban for the prevention of deep-vein thrombosis or pulmonary embolism after total hip or knee arthroplasty.

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

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Researcher sought to determine the effectiveness of hydroxychloroquine vs placebo as an analgesic treatment of hand osteoarthritis.

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

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The effects of combination COX-2 inhibitor therapy with metformin on joint replacement rates were examined in patients with osteoarthritis and diabetes.

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

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In older patients with knee OA, pain expectancy may affect the pain experience after genuine and sham electroacupuncture.

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

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Patients with end-stage knee or hip osteoarthritis may often experience neuropathic pain, particularly at rest.

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

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Use of the 2006 Orlando criteria vs the 2007 Budapest criteria for diagnosis of CRPS may lead to misdiagnosis of unexplained pain after TKA.

Knee Replacement Rates and Outcomes Vary by Race in the United States

Knee Replacement Rates and Outcomes Vary by Race in the United States

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There is a need for programs that are designed to decrease disparities in joint replacement use among various populations.

Many NSAID Users Exceed Daily Dose Limit

Many NSAID Users Exceed Daily Dose Limit

Many individuals who use nonsteroidal anti-inflammatory drugs tend to exceed the daily dose limit.

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

NSAID Safety Differences in Osteoarthritis, Rheumatoid Arthritis Compared

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The use of celecoxib in patients with OA and RA was associated with a similar or a lower risk for cardiovascular, gastrointestinal, and renal adverse events compared with ibuprofen and naproxen.

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

Does Acupuncture Decrease Pain After Joint Replacement Surgery?

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Routine rehabilitation therapy along with adjunctive acupuncture may not provide a significant benefit over exercise, after total knee replacement.

Do Genicular Nerve Blocks Predict Radiofrequency Ablation Outcomes in Osteoarthritis?

Do Genicular Nerve Blocks Predict Radiofrequency Ablation Outcomes in Osteoarthritis?

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Genicular nerve block may not predict pain relief following genicular nerve cooled radiofrequency ablation in patients with chronic knee pain due to OA.

Examining Symptomatic, Radiographic Benefits of Bisphosphonate Treatment in Knee Osteoarthritis

Examining Symptomatic, Radiographic Benefits of Bisphosphonate Treatment in Knee Osteoarthritis

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Seven studies were included in a meta-analysis examining the potential benefit of bisphosphonate therapy in knee osteoarthritis.

Intra-articular Betamethasone Associated With Increased Insulin Resistance in Type 2 Diabetes

Intra-articular Betamethasone Associated With Increased Insulin Resistance in Type 2 Diabetes

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Insulin resistance may be experienced by patients with T2D who receive an intra-articulate corticosteroid of betamethasone injection at the knee joint.

Clinician Counseling for Exercise Increased Among Adults With Arthritis Between 2002 and 2014

Clinician Counseling for Exercise Increased Among Adults With Arthritis Between 2002 and 2014

There was an increase in the age-adjusted prevalence of reporting health care provider counseling for exercise in adults with arthritis.

Inflammation in Rheumatic Diseases May Be Associated With Increased Risk of Dementia

Inflammation in Rheumatic Diseases May Be Associated With Increased Risk of Dementia

Patients with rheumatic diseases have a higher risk for dementia.

Association Between Physical Activity and Joint Symptoms Modified by BMI in Middle-Aged Women

Association Between Physical Activity and Joint Symptoms Modified by BMI in Middle-Aged Women

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A study sought to determine whether physical activity has a protective effect against development of joint symptoms in middle-aged women.

Short- and Long-Acting Opioids Equally Effective for Osteoarthritis Pain Management

Short- and Long-Acting Opioids Equally Effective for Osteoarthritis Pain Management

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Short-acting opioids are comparable with long-acting opioid medications for managing pain in patients with chronic osteoarthritis.

Cooled Radiofrequency Ablation Effective for Osteoarthritis Knee Pain

Cooled Radiofrequency Ablation Effective for Osteoarthritis Knee Pain

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For patients with osteoarthritis-related knee pain, cooled radiofrequency ablation may provide greater pain relief compared with steroid injections.

Knee Osteoarthritis Patients Receive Little Benefit From Bisphosphonates

Knee Osteoarthritis Patients Receive Little Benefit From Bisphosphonates

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Bisphosphonates did not show to be beneficial for patients with knee osteoarthritis.

Inhibition of the Wnt Pathway: Potential Benefits for Osteoarthritis

Inhibition of the Wnt Pathway: Potential Benefits for Osteoarthritis

Allan Gibofsky, MD, discusses inhibition of the Wnt pathway and its potential benefits for the treatment of osteoarthritis.

Hydroxychloroquine vs Placebo for Patients With Osteoarthritis of the Hands

Hydroxychloroquine vs Placebo for Patients With Osteoarthritis of the Hands

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Hydroxychloroquine is not significantly more effective in treating osteoarthritis of the hand than placebo.

FDA Advises Recall: Limbrel May Be Linked to Drug-Induced Liver Injury

FDA Advises Recall: Limbrel May Be Linked to Drug-Induced Liver Injury

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As of November 21, 2017, the FDA received 194 adverse event reports about the unapproved osteoarthritis treatment Limbrel.

Risk for Prosthetic Joint Infection, Surgical Revision After Total Joint Arthroplasty in RA

Risk for Prosthetic Joint Infection, Surgical Revision After Total Joint Arthroplasty in RA

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Patients with rheumatoid arthritis may be at increased risk for prosthetic joint infection and death after total knee or hip arthroplasty, compared with patients with osteoarthritis.

Extended-Release Steroidal Injectable Suspension Available for Knee OA

Extended-Release Steroidal Injectable Suspension Available for Knee OA

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Zilretta is now available for pain management in knee osteoarthritis.

Sarcopenic Obesity in Osteoarthritis vs Rheumatoid Arthritis

Sarcopenic Obesity in Osteoarthritis vs Rheumatoid Arthritis

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Individuals with osteoarthritis may exhibit a higher prevalence of sarcopenic obesity, compared with patients with rheumatoid arthritis.

Online Consultation System Benefits Rheumatic Disease Management

Online Consultation System Benefits Rheumatic Disease Management

The SSDM series of applications is cost-effective for patients of rheumatologists.

Thoracic Manifestations in Connective Tissue Disease: A Review

Thoracic Manifestations in Connective Tissue Disease: A Review

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Thoracic manifestations are common in connective tissue disease, also called collagen vascular disease.

Improved Function, Pain in Hand Osteoarthritis With Pregabalin

Improved Function, Pain in Hand Osteoarthritis With Pregabalin

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In patients with hand osteoarthritis, pregabalin was shown to improve hand pain.

Wnt Pathway Inhibition Alleviates Symptoms of Knee Osteoarthritis

Wnt Pathway Inhibition Alleviates Symptoms of Knee Osteoarthritis

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Inhibition of the Wnt pathway with the small molecule SM04690 was shown to improve pain and maintain or improve radiographic outcomes in patients with knee osteoarthritis.

THA, TKA Patients Increase Use of Multimodal Approaches for Postoperative Pain

THA, TKA Patients Increase Use of Multimodal Approaches for Postoperative Pain

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In patients undergoing THA or TKA, the use of multimodal approaches for postoperative pain is increasing.

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