Osteoarthritis

Zilretta Benefits 'Real-World' Patients With Knee OA, Says Study

Zilretta Benefits 'Real-World' Patients With Knee OA, Says Study

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Interim data have been released from a phase 3b, open-label study that evaluated the safety and tolerability of repeat administration of Zilretta in patients with knee osteoarthritis.

Examining Unmet Needs of Joint Disease Associated With Calcium Pyrophosphate Crystal Deposition

Examining Unmet Needs of Joint Disease Associated With Calcium Pyrophosphate Crystal Deposition

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Addressing the challenges associated with clinical management of calcium pyrophosphate crystal deposition must start with understanding the unmet needs of associated joint damage and establishing a clearly defined strategy to address these needs.

Prevalence of Arthritis Assessed in the United States

Prevalence of Arthritis Assessed in the United States

Men, non-Hispanic blacks, and participants with low income or obesity had the most pronounced decrease in RA prevalence.

Tibiofemoral MRI May Be Predictive of Radiographic Knee OA in Overweight, Obese Women

Tibiofemoral MRI May Be Predictive of Radiographic Knee OA in Overweight, Obese Women

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Researchers sought to determine the predictive value of tibiofemoral MRI, patellofemoral MRI, and KLG1 for the incidence of clinical or radiographic knee OA.

GI Safety Compared for NSAIDs in Patients With Arthritis

GI Safety Compared for NSAIDs in Patients With Arthritis

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The randomized, double-blind, controlled trial (N=24,081) included patients with rheumatoid arthritis or osteoarthritis who required chronic NSAID treatment.

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

Intramuscular Triamcinolone Acetate Injection for OA Hip Pain

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In patients with painful hip osteoarthritis, an intramuscular glucocorticoid injection may effectively alleviate hip pain in the short-term.

Radiofrequency Ablation for Chronic Hip Pain in Osteoarthritis: Reviewing the Evidence

Radiofrequency Ablation for Chronic Hip Pain in Osteoarthritis: Reviewing the Evidence

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The available evidence suggests that radiofrequency ablation is a feasible treatment option for chronic hip pain associated with degenerative diseases.

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

Subcutaneous vs Intravenous Tanezumab for Knee, Hip Osteoarthritis

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Intravenous and subcutaneous administration of tanezumab may provide similar analgesia and tolerability in patients with hip or knee osteoarthritis.

Bariatric Surgery Lessens Knee OA Pain More in Certain Patients

Bariatric Surgery Lessens Knee OA Pain More in Certain Patients

Laparoscopic gastric band surgery is associated with more improvement in knee osteoarthritis in younger patients and in patients without prior knee injury.

Intra-articular Knee Injection Increases Intraocular Pressure in Osteoarthritis

Intra-articular Knee Injection Increases Intraocular Pressure in Osteoarthritis

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Intraocular pressure was increased in patients who underwent a triamcinolone steroid knee injection, but not in patients who received a hyaluronic acid knee injection.

Managing Dietary Supplements and Complementary Medicines in Osteoarthritis

Managing Dietary Supplements and Complementary Medicines in Osteoarthritis

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Dietary supplements are widely used by patients with osteoarthritis, but the safety and efficacy of supplements remain unclear and are often misconstrued by mainstream media.

Total Hip Arthroplasty Revision Rate Examined From 2007 to 2013

Total Hip Arthroplasty Revision Rate Examined From 2007 to 2013

Patients aged 45 to 64 had an increase in the total hip arthroplasty revision rate from 2007 to 2013.

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

Reproductive, Hormonal Factors Affect Risk for Total Knee Arthroplasty in Women

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Researchers sought to identify associations of female reproductive factors with incidence of total knee arthroplasty in osteoarthritis.

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

Opioids vs Nonopioid Medications for Chronic Back, Knee, and Hip Osteoarthritis Pain

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Opioids and nonopioid analgesics were found to provide similar improvements in pain-related function in patients with chronic back pain or knee or hip OA pain.

Geniculate Artery Embolization Reduces Pain, Disability in Knee Osteoarthritis

Geniculate Artery Embolization Reduces Pain, Disability in Knee Osteoarthritis

Reduction in pain and disability for knee OA is linked with minimally invasive, image-guided geniculate artery embolization.

Predicting Response to Intra-Articular Hyaluronic Acid Treatment in Knee Osteoarthritis

Predicting Response to Intra-Articular Hyaluronic Acid Treatment in Knee Osteoarthritis

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Investigators sought to identify determinants associated with improved response to intra-articular hyaluronic acid treatment in individuals with knee OA.

Painful Temporomandibular Joint Osteoarthritis: Glucosamine Supplements vs Ibuprofen

Painful Temporomandibular Joint Osteoarthritis: Glucosamine Supplements vs Ibuprofen

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The effects of glucosamine supplements were not superior to the effects of ibuprofen in the treatment of patients with temporomandibular joint OA.

Efficacy of Colchicine for the Reduction of Symptoms in Knee Osteoarthritis

Efficacy of Colchicine for the Reduction of Symptoms in Knee Osteoarthritis

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Researchers sought to investigate the effectiveness of colchicine on pain and function in symptomatic knee osteoarthritis.

Costs of Stem Cell Therapy Quantified for Knee Osteoarthritis

Costs of Stem Cell Therapy Quantified for Knee Osteoarthritis

Stem cell therapy for knee osteoarthritis is expanding, with costs exceeding $5000 for each therapy.

Pain Outcomes in Knee Osteoarthritis: Total Knee Replacement vs Nonsurgical Interventions

Pain Outcomes in Knee Osteoarthritis: Total Knee Replacement vs Nonsurgical Interventions

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Low pressure pain thresholds at baseline predicted worse pain outcomes after total knee replacement surgery, but did not predict outcomes after nonsurgical interventions.

Exercise Interventions in Knee Osteoarthritis: Physical Therapy vs Tai Chi

Exercise Interventions in Knee Osteoarthritis: Physical Therapy vs Tai Chi

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The dose-response effects of physical therapy and tai chi for patients with knee OA are approximately linear.

Early Radiographic Knee OA to Joint Arthroplasty: Factors of Structural Progression

Early Radiographic Knee OA to Joint Arthroplasty: Factors of Structural Progression

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More than half of patients with no or mild radiographic knee osteoarthritis prior to knee replacement surgery progressed to severe osteoarthritis over 4 years of follow-up.

Aspirin Similar to Rivaroxaban for VTE Prophylaxis After Hip, Knee Arthroplasty

Aspirin Similar to Rivaroxaban for VTE Prophylaxis After Hip, Knee Arthroplasty

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Results from the EPCAT II trial show that aspirin was not significantly different from rivaroxaban for the prevention of deep vein thrombosis or pulmonary embolism after total hip or knee arthroplasty.

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

Hand Osteoarthritis Symptoms Not Reduced With Hydroxychloroquine

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Researcher sought to determine the effectiveness of hydroxychloroquine vs placebo as an analgesic treatment of hand osteoarthritis.

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

Joint Replacement Rates in OA With Diabetes: Effects of COX-2 Inhibitors Plus Metformin

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The effects of combination COX-2 inhibitor therapy with metformin on joint replacement rates were examined in patients with osteoarthritis and diabetes.

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

Pain Expectancy Affects Pain Experience After Electroacupuncture in OA

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In older patients with knee OA, pain expectancy may affect the pain experience after genuine and sham electroacupuncture.

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

Neuropathic Pain Commonly Found in End-Stage Lower Extremity Osteoarthritis

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Patients with end-stage knee or hip osteoarthritis may often experience neuropathic pain, particularly at rest.

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

Diagnosing Complex Regional Pain Syndrome After Total Knee Arthroplasty

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Use of the 2006 Orlando criteria vs the 2007 Budapest criteria for diagnosis of CRPS may lead to misdiagnosis of unexplained pain after TKA.

Knee Replacement Rates and Outcomes Vary by Race in the United States

Knee Replacement Rates and Outcomes Vary by Race in the United States

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There is a need for programs that are designed to decrease disparities in joint replacement use among various populations.

Many NSAID Users Exceed Daily Dose Limit

Many NSAID Users Exceed Daily Dose Limit

Many individuals who use nonsteroidal anti-inflammatory drugs tend to exceed the daily dose limit.

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