Kenneth Saag, MD, president of the National Osteoporosis Foundation (NOF), co-chair of the National Bone Health Alliance, and Rheumatology Advisor advisory board member, reports on the recent changes that have led to the current state of osteoporosis treatment in the US.
Treatment with denosumab may increase bone mineral density in older women with primary hyperparathyroidism-related osteoporosis.
Seventy-five randomized controlled trials were included in a meta-analysis comparing DDP-4 inhibitors with placebo and other diabetes medications.
Routine vitamin D and calcium supplementation in older adults is not supported for lowering the incidence of osteoporosis-related fractures.
Among older adults with functional limitations, a long-term physical activity program was not associated with reduced frailty risk.
Lower rates for hip fractures in women are linked to high intake of fermented milk products, along with fruits and vegetables.
The risk for venous thromboembolism among strontium ranelate, denosumab, teriparatide, alendronate, and other bisphosphonates was evaluated by investigators.
Hip fracture repair was linked to higher rates of 30-day mortality and post-operative complications when time between hospital arrival and surgery exceeded 24 hours.
Tocilizumab treatment for 2 years was shown to reduce levels of bone loss in patients with ACPA-positive RA.
In patients with hip fractures, the use of a regional nerve block may provide pain relief, and decrease the risk for pneumonia.
Caffeine intake among women older than 50 may have a small association with a decrease in BMD, and may increase risk of hip fractures.
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