Compared with growth hormone treatment, 1 year of placebo after attainment of adult height does not decrease bone mineral density in young adults with Prader-Willi syndrome.
Results confirm that failure load and stiffness of bone are significantly impaired in men and women with rheumatoid arthritis.
SSRI use was found to be associated with reduced bone mineral density in the lumbar spine.
The SCOOP study evaluated screenings aimed at identifying older women who are at increased risk for fragility fractures.
Researchers examined the effects of abaloparatide in a subgroup of women older than 80 years from the ACTIVE trial.
Gastric bypass surgery can have damaging effects on bone mass as early as 6 months postoperatively.
Investigators sought to determine whether vertebral trabecular attenuation values measured on routine body CT scans can predict future osteoporotic fractures at multiple skeletal sites.
Treatment with denosumab may increase bone mineral density in older women with primary hyperparathyroidism-related osteoporosis.
Seventy-five randomized controlled trials were included in a meta-analysis comparing DDP-4 inhibitors with placebo and other diabetes medications.
Routine vitamin D and calcium supplementation in older adults is not supported for lowering the incidence of osteoporosis-related fractures.
Among older adults with functional limitations, a long-term physical activity program was not associated with reduced frailty risk.
Lower rates for hip fractures in women are linked to high intake of fermented milk products, along with fruits and vegetables.
The risk for venous thromboembolism among strontium ranelate, denosumab, teriparatide, alendronate, and other bisphosphonates was evaluated by investigators.
Hip fracture repair was linked to higher rates of 30-day mortality and post-operative complications when time between hospital arrival and surgery exceeded 24 hours.
Tocilizumab treatment for 2 years was shown to reduce levels of bone loss in patients with ACPA-positive RA.
In patients with hip fractures, the use of a regional nerve block may provide pain relief, and decrease the risk for pneumonia.
Caffeine intake among women older than 50 may have a small association with a decrease in BMD, and may increase risk of hip fractures.
Rapid loss of bone density is linked with the use of insulin for T2D.
This suggests to us that, as is the standard now, when we use an anabolic agent, we can add in an antiresorptive such as alendronate, and see continued sustained reduction in fracture risk.
Growth hormone therapy may reduce the risk for fracture in patients with osteoporosis.
Greater visceral and/or subcutaneous adiposity may have an important role in bone growth during adolescence.
Investigators evaluated the efficacy of teriparatide vs risedronate in preventing clinical and vertebral fracture in post-menopausal women with existing vertebral fractures.
All women 65, high-risk postmenopausal women 65 should undergo bone measurement testing.
In postmenopausal women at high risk for fracture, treatment with romosozumab for 12 months, followed by alendronate, was associated with significantly fewer hip fractures than treatment with alendronate alone.
Higher dietary fiber and fruit fiber is protective against bone loss at the femoral neck in men.
The use of vertebral fracture assessment has shown adequate performance for the detection of vertebral fractures.
Prolonged antiresorptive activity of ≥3 years has been associated with single zoledronate doses between 1 and 5 mg in postmenopausal women with osteopenia.
Tymlos is approved to treat postmenopausal women with osteoporosis at high risk for fracture.
Clinically undiagnossed radiographic VFs are linked to increased back pain symptoms.
Quality of life is similarly impacted by osteoporotic fractures and complications of diabetes.
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